A possible regulation of negative factor (Nef) activity of human immunodeficiency virus type 1 by the viral protease.

scientific article published in July 1994

A possible regulation of negative factor (Nef) activity of human immunodeficiency virus type 1 by the viral protease. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1432-1033.1994.TB19029.X
P698PubMed publication ID8055930
P5875ResearchGate publication ID15143178

P50authorHans-Georg KräusslichQ1576991
Hans Robert KalbitzerQ19284863
Jan KonvalinkaQ28360189
P2093author name stringR Kellner
J Freund
V Wolber
P2860cites workSerine phosphorylation-independent downregulation of cell-surface CD4 by nefQ22251290
Importance of the nef gene for maintenance of high virus loads and for development of AIDSQ29618369
Specificity mapping of HIV-1 protease by reduced bond inhibitors.Q39407416
Effect of myristoylation on p27nef subcellular distribution and suppression of HIV-LTR transcriptionQ41635961
Purification and characterization of human immunodeficiency virus type 1 nef gene product expressed by a recombinant baculovirusQ42071857
HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene productQ59048755
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)589-593
P577publication date1994-07-01
P1433published inFEBS JournalQ1388041
P1476titleA possible regulation of negative factor (Nef) activity of human immunodeficiency virus type 1 by the viral protease
P478volume223

Reverse relations

cites work (P2860)
Q41718191AIDS pathogenesis: the role of accessory gene mutations, leading to formation of long-lived persistently infected cells and/or apoptosis-inducing HIV-1 particles.
Q41813849Alkylating HIV-1 Nef - a potential way of HIV intervention
Q36874356Bioinformatic approaches for modeling the substrate specificity of HIV-1 protease: an overview
Q39684211Changes in human immunodeficiency virus type 1 Gag at positions L449 and P453 are linked to I50V protease mutants in vivo and cause reduction of sensitivity to amprenavir and improved viral fitness in vitro
Q41989123Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein
Q45784368Cleavage of recombinant and cell derived human immunodeficiency virus 1 (HIV-1) Nef protein by HIV-1 protease
Q40261243Comparative genetic variability in HIV-1 subtype C nef gene in early age groups of infants
Q39736736Disassembly of human immunodeficiency virus type 1 cores in vitro reveals association of Nef with the subviral ribonucleoprotein complex
Q58136237Evidence for the association of Nef protein with HIV-2 virions
Q28538038HIV-1 Nef inhibits Protease activity and its absence alters protein content of mature viral particles
Q34050688HIV-1 protease: maturation, enzyme specificity, and drug resistance.
Q33866230Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions
Q42125314Human immunodeficiency virus type 1 Nef incorporation into virions does not increase infectivity
Q39601382Human immunodeficiency virus type 1 protease cleavage site mutations associated with protease inhibitor cross-resistance selected by indinavir, ritonavir, and/or saquinavir
Q39443718In-silico designing of a potent analogue against HIV-1 Nef protein and protease by predicting its interaction network with host cell proteins
Q39875739Influence of extended mutations of the HIV-1 transframe protein p6 on Nef-dependent viral replication and infectivity in vitro
Q34185928Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner
Q41142054Nef and the Nef-associated kinase
Q36315000Pol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation
Q34010283Positive and negative aspects of the human immunodeficiency virus protease: development of inhibitors versus its role in AIDS pathogenesis
Q35863401Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein
Q35601697Proteomic profiling of SupT1 cells reveal modulation of host proteins by HIV-1 Nef variants
Q33180343Recombinant nef HIV-IIIB protein is toxic to human neurons in culture
Q30176531Refined solution structure and backbone dynamics of HIV-1 Nef.
Q42223515Sequence heterogeneity in human immunodeficiency virus type 1 nef in patients presenting with rapid progression and delayed progression to AIDS.
Q39877488Specific cleavage sites of Nef proteins from human immunodeficiency virus types 1 and 2 for the viral proteases
Q24522550Structure--function relationships in HIV-1 Nef.
Q30160188The HIV-1 Nef protein as a target for antiretroviral therapy
Q24322710The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling
Q41338314The positive influence of Nef on viral infectivity
Q33783315The proteolytic cleavage of human immunodeficiency virus type 1 Nef does not correlate with its ability to stimulate virion infectivity.
Q28647550The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase
Q33785282Virion incorporation of human immunodeficiency virus type 1 Nef is mediated by a bipartite membrane-targeting signal: analysis of its role in enhancement of viral infectivity.

Search more.