In vivo adenovirus-mediated delivery of a uPA/uPAR antagonist reduces retinal neovascularization in a mouse model of retinopathy

scientific article published on December 1, 2003

In vivo adenovirus-mediated delivery of a uPA/uPAR antagonist reduces retinal neovascularization in a mouse model of retinopathy is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1038061706
P356DOI10.1038/SJ.GT.3302122
P953full work available at URLhttps://www.nature.com/articles/3302122.pdf
https://www.nature.com/articles/3302122
P698PubMed publication ID14595383
P5875ResearchGate publication ID9029207

P50authorMagali Saint-GeniezQ58898025
Michel Jean Robert PerricaudetQ64398414
P2093author name stringM. Menasche
D. Marchant
M. Perricaudet
A. Provost
M. Abitbol
L. Le Gat
K. Gogat
C. Bouquet
D. Darland
L. Van Den Berghe
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Blindness caused by diabetic retinopathyQ69781866
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Endostatin: an endogenous inhibitor of angiogenesis and tumor growthQ24315369
Pigment epithelium-derived factor inhibits retinal and choroidal neovascularizationQ28203561
Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularizationQ31081886
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Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularizationQ34749337
Gene therapy for ocular angiogenesis.Q35061497
Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularizationQ35745444
Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity.Q35897076
Recombinational construction in Escherichia coli of infectious adenoviral genomesQ35997183
Design of yeast-secreted albumin derivatives for human therapy: biological and antiviral properties of a serum albumin-CD4 genetic conjugateQ36868245
The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.Q40241912
Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc bindingQ40935045
Vascular endothelial growth factor and the eye: biochemical mechanisms of action and implications for novel therapiesQ41607468
Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB.Q43852725
Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1.Q44763476
Systemic delivery of antiangiogenic adenovirus AdmATF induces liver resistance to metastasis and prolongs survival of miceQ44839939
Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in miceQ45858195
Adenovirus-mediated gene transfer of urokinase plasminogen inhibitor inhibits angiogenesis in experimental arthritisQ45883663
P433issue25
P407language of work or nameEnglishQ1860
P921main subjectgeneticsQ7162
AdenoviridaeQ193447
neovascularizationQ1281049
molecular medicineQ3523816
P304page(s)2098-2103
P577publication date2003-12-01
P1433published inGene TherapyQ15763095
P1476titleIn vivo adenovirus-mediated delivery of a uPA/uPAR antagonist reduces retinal neovascularization in a mouse model of retinopathy
P478volume10

Reverse relations

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Q35594134Current status of gene delivery and gene therapy in lacrimal gland using viral vectors.
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Q58579972Diabetic Retinopathy: A complex pathophysiology requiring novel therapeutic strategies
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Q46377186Intraocular Properties of a Repository Urokinase Receptor Antagonist Å36 Peptide in Rabbits
Q64239571Novel stem cell and gene therapy in diabetic retinopathy, age related macular degeneration, and retinitis pigmentosa
Q38013679Novel targets against retinal angiogenesis in diabetic retinopathy
Q36108106Prospectives for gene therapy of retinal degenerations
Q41878292Relationship between urokinase-type plasminogen activator receptor and vascular endothelial growth factor expression and metastasis of gallbladder cancer
Q36414191Role of urokinase inhibitors in choroidal neovascularization
Q92703699The uPAR System as a Potential Therapeutic Target in the Diseased Eye
Q35124141Urokinase and its receptors in chronic kidney disease.