Several serum proteins significantly decrease inflammatory response to lipid-based non-viral vectors

scientific article published on 20 November 2007

Several serum proteins significantly decrease inflammatory response to lipid-based non-viral vectors is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.MT.6300356
P698PubMed publication ID18026169
P5875ResearchGate publication ID5821407

P2093author name stringFeng Liu
Leaf Huang
Christine C Conwell
P2860cites workImportant role of serum proteins associated on the surface of particles in their hepatic dispositionQ74763435
Transferrin-facilitated lipofection gene delivery strategy: characterization of the transfection complexes and intracellular traffickingQ78503154
Lipofection: a highly efficient, lipid-mediated DNA-transfection procedureQ24634002
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Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicityQ33337328
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Effect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cellsQ38338150
Codelivery of NF-kappaB decoy-related oligodeoxynucleotide improves LPD-mediated systemic gene transferQ38359365
Mechanistic studies of sequential injection of cationic liposome and plasmid DNA.Q40359100
Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifsQ41921336
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Targeted gene delivery to cancer cells: directed assembly of nanometric DNA particles coated with folic acidQ44482465
Identification of human plasma proteins that bind to cationic lipid/DNA complex and analysis of their effects on transfection efficiency: implications for intravenous gene transferQ44541949
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Factors governing the in vivo tissue uptake of transferrin-coupled polyethylene glycol liposomes in vivoQ45003131
Enhanced gene expression in mouse lung by prolonging the retention time of intravenously injected plasmid DNA.Q45855918
Novel nonviral vectors target cellular signaling pathways: regulated gene expression and reduced toxicityQ45866201
Efficient in vivo gene transfer by PCR amplified fragment with reduced inflammatory activityQ45877903
The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexesQ45888099
Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene deliveryQ45889911
Apolipoprotein A-I induces IL-10 and PGE2 production in human monocytes and inhibits dendritic cell differentiation and maturation.Q46783416
Contribution of Plasmid DNA to Inflammation in the Lung after Administration of Cationic Lipid:pDNA ComplexesQ62566769
The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivoQ73022551
Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivoQ73850372
Identification of proteins mediating clearance of liposomes using a liver perfusion systemQ73850378
P433issue2
P304page(s)370-377
P577publication date2007-11-20
P1433published inMolecular TherapyQ15762400
P1476titleSeveral serum proteins significantly decrease inflammatory response to lipid-based non-viral vectors
P478volume16

Reverse relations

cites work (P2860)
Q40336026Amphiphilic polymers formed from ring-opening polymerization: a strategy for the enhancement of gene delivery.
Q36957725Cellular distribution of injected PLGA-nanoparticles in the liver
Q37627725Distinct pathways of humoral and cellular immunity induced with the mucosal administration of a nanoemulsion adjuvant.
Q37219628Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
Q36528415Polymer nanoparticles encapsulating siRNA for treatment of HSV-2 genital infection
Q37503636Sustained delivery of proangiogenic microRNA-132 by nanoparticle transfection improves endothelial cell transplantation.

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