Mumps virus infects beta cells in human fetal islet cell cultures upregulating the expression of HLA class I molecules.

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Mumps virus infects beta cells in human fetal islet cell cultures upregulating the expression of HLA class I molecules. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1037487599
P356DOI10.1007/BF00400853
P698PubMed publication ID1311693

P50authorHeikki HyotyQ59688368
P2093author name stringP Leinikki
L Koskinen
P Parkkonen
P2860cites workDiabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic β cellsQ59073388
HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxinQ59083904
In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitisQ67296143
Mumps infections in the etiology of type 1 (insulin-dependent) diabetesQ68061501
Large-scale production of fetal porcine pancreatic isletlike cell clusters. An experimental tool for studies of islet cell differentiation and xenotransplantationQ68129005
Morphology, yield and functional integrity of islet-like cell clusters in tissue culture of human fetal pancreata obtained after different means of abortionQ68147847
Viruses and cytokines: evidence for multiple roles in pancreatic beta cell destruction in type 1 insulin-dependent diabetes mellitusQ69352205
Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitusQ69911018
Growth and hormonal content of human fetal pancreas passaged in athymic miceQ70280548
Interferon-gamma induces the expression of HLA-A,B,C but not HLA-DR on human pancreatic beta-cellsQ70284568
Differential expression and regulation of MHC products in the endocrine and exocrine cells of the human pancreasQ70315600
[Diabetes mellitus as a complication of epidemic parotitis.]Q78488513
IDDM in BB rats. Enhanced MHC class I heavy-chain gene expression in pancreatic islets.Q34163877
Virus-induced diabetes mellitus. XV. Beta cell damage and insulin-dependent hyperglycemia in mice infected with coxsackie virus B4Q36341943
Effect of herpes simplex virus types 1 and 2 on surface expression of class I major histocompatibility complex antigens on infected cellsQ36854257
Adenoviruses of subgenera B, C, D, and E modulate cell-surface expression of major histocompatibility complex class I antigensQ37412250
In type 1 diabetes, does a non-cytopathic viral infection of insulin-secreting B-cells initiate the disease process leading to their autoimmune destruction?Q38260721
Molecular mimicry as a mechanism for virus-induced autoimmunityQ38610595
MHC molecules and beta-cell destruction. Immune and nonimmune mechanismsQ38650216
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Insulin-dependent (juvenile-onset, type 1) diabetes mellitus Coxsackie B viruses revisitedQ39142860
Insulin-dependent diabetes: a possible viral diseaseQ40081327
Infection of human pancreatic beta cell cultures with mumps virusQ40850817
Virus-induced Diabetes Mellitus: XI. Replication of Coxsackie B3 Virus in Human Pancreatic Beta Cell CulturesQ40899158
Method for Large-Scale Isolation of Pancreatic Islets by Tissue Culture of Fetal Rat PancreasQ41048445
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cellsQ41357447
Interferon-independent increases in class I major histocompatibility complex antigen expression follow flavivirus infectionQ42990599
Aberrant expression of HLA-DR antigens by insulin-containing beta-cells in recent-onset type I diabetes mellitusQ43488548
Reovirus infection enhances expression of class I MHC proteins on human beta-cell and rat RINm5F cellQ43811529
Retrovirus-induced changes in major histocompatibility complex antigen expression influence susceptibility to lysis by cytotoxic T lymphocytesQ44325114
Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gammaQ44506225
Is mumps virus an etiologic factor in juvenile diabetes mellitus?Q44536001
The reactions of monoclonal antibodies with structural proteins of mumps virusQ45804439
Enhancement of class I HLA antigen expression by cytomegalovirus: role in amplification of virus infectionQ45840957
Relation of antecedent illness to development of diabetes in children.Q55153730
P433issue1
P921main subjectmumps virusQ1952649
mumpsQ176741
P304page(s)63-69
P577publication date1992-01-01
P1433published inDiabetologiaQ5270140
P1476titleMumps virus infects beta cells in human fetal islet cell cultures upregulating the expression of HLA class I molecules
P478volume35