Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results

scientific article

Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1044480489
P356DOI10.1038/SJ.CGT.7700851
P698PubMed publication ID15891772
P5875ResearchGate publication ID7849117

P50authorLuisa BarzonQ60011989
Giorgio PalùQ67154939
Monia PacentiQ114452192
Elisa FranchinQ114452193
P2093author name stringFederico Colombo
Daniela Danieli
Vittore Pinna
Mariano Zanusso
P2860cites workLMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1Q28210584
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Influence of the bystander effect on HSV-tk/GCV gene therapy. A reviewQ34791457
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Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumorsQ35228764
Endocrine aspects of cancer gene therapyQ35652687
High-titer packaging cells producing recombinant retroviruses resistant to human serumQ35851698
Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenovirusesQ40611932
Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovirQ41576545
Gene therapy of thyroid cancer via retrovirally-driven combined expression of human interleukin-2 and herpes simplex virus thymidine kinaseQ42806173
Production and characterization of a bicistronic Moloney-based retroviral vector expressing human interleukin 2 and herpes simplex virus thymidine kinase for gene therapy of cancerQ42824650
Immune response induced by retrovirus-mediated HSV-tk/GCV pharmacogene therapy in patients with glioblastoma multiforme.Q43636591
Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humansQ43689849
Systemic activation of the immune system during ganciclovir treatment following intratumoral herpes simplex virus type 1 thymidine kinase gene transfer in an adolescent ependymoma patient.Q43945636
Transcriptionally targeted retroviral vector for combined suicide and immunomodulating gene therapy of thyroid cancerQ44204081
Volume of residual disease as a predictor of outcome in adult patients with recurrent supratentorial glioblastomas multiforme who are undergoing chemotherapyQ44742482
Response criteria for phase II studies of supratentorial malignant gliomaQ44781447
AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled studyQ45127753
A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.Q45739549
A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study GroupQ45862712
Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical resultsQ45863348
Biosafety monitoring of patients receiving intracerebral injections of murine retroviral vector producer cellsQ45887851
Gene stereotactic neurosurgery for recurrent malignant gliomasQ45888902
Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cellsQ48587406
Incidence of risk of thromboembolism during treatment high-grade gliomas: a prospective studyQ48590023
Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.Q54635100
Characterization of the reverse transcriptase from a new retrovirus (HTLV) produced by a human cutaneous T-cell lymphoma cell lineQ55245697
A Phase I/II Study of Herpes Simplex Virus Type 1 Thymidine Kinase “Suicide” Gene Therapy for Recurrent GlioblastomaQ58659735
P433issue10
P921main subjectpatientQ181600
gene therapyQ213901
glioblastomaQ282142
P304page(s)835-848
P577publication date2005-10-01
P1433published inCancer Gene TherapyQ15763088
P1476titleCombined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results
P478volume12

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cites work (P2860)
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