Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis

scientific article

Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0736-0266(01)00083-3
P698PubMed publication ID11918293

P2093author name stringRegis J O'Keefe
Edward M Schwarz
J Edward Puzas
Randy N Rosier
J Jeffrey Goater
P2860cites workOsteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
RANK is essential for osteoclast and lymph node developmentQ24598872
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligandQ24653311
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
The effect of ultra-high molecular weight polyethylene wear debris on MG63 osteosarcoma cells in vitroQ28374594
Immunological defects in mice with a targeted disruption in Bcl-3Q28506495
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgeneQ37265676
Primary total hip arthroplasty with a cementless porous-coated anatomic total hip prosthesis: 10- to 12-year results of prospective and consecutive seriesQ39225366
Tumor necrosis factor-alpha/nuclear transcription factor-kappaB signaling in periprosthetic osteolysisQ40862558
Response of three murine macrophage populations to particulate debris: bone resorption in organ culturesQ41444921
Studies of the mechanism by which the mechanical failure of polymethylmethacrylate leads to bone resorptionQ41551181
Effects of interleukin-1 on bone turnover in normal miceQ43625701
Charnley total hip arthroplasty in patients less than fifty years old. A twenty to twenty-five-year follow-up note.Q44108884
Gene therapy for rheumatic diseasesQ45855770
Gene therapy -- promises, problems and prospectsQ45883584
Ultrahigh molecular weight polyethylene particles have direct effects on proliferation, differentiation, and local factor production of MG63 osteoblast-like cellsQ47270034
NF-kappa B regulates VCAM-1 expression on fibroblast-like synoviocytesQ64380752
Bone formation and bone resorption in failed total joint arthroplasties: histomorphometric analysis with histochemical and immunohistochemical techniqueQ71175942
Interleukin-1 production by activated macrophages surrounding loosened orthopaedic implants: a potential role in osteolysisQ71618460
Prosthetic metals interfere with the functions of human osteoblast cells in vitroQ73422144
Quantitative small-animal surrogate to evaluate drug efficacy in preventing wear debris-induced osteolysisQ73472299
Outcome of Charnley total hip replacement across a single health region in England: the results at five years from a regional hip registerQ78175828
P433issue2
P921main subjectgene therapyQ213901
osteolysisQ2035084
P304page(s)169-173
P577publication date2002-03-01
P1433published inJournal of Orthopaedic ResearchQ6295700
P1476titleEfficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis
P478volume20