RLIM suppresses hepatocellular carcinogenesis by up-regulating p15 and p21.

scientific article published on 15 September 2017

RLIM suppresses hepatocellular carcinogenesis by up-regulating p15 and p21. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.20904
P932PMC publication ID5669951
P698PubMed publication ID29137325

P2093author name stringLin Wang
Yongsheng Huang
Lan Zhou
Yingjie Zhao
Chuang Li
Jiahui Li
Meng Nie
P2860cites workAn alternative pathway for gene regulation by MycQ24532791
Myc represses transcription through recruitment of DNA methyltransferase corepressorQ24557458
Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancerQ24646768
Direct activation of TERT transcription by c-MYC.Q40973563
DNA methylation markers and serum α-fetoprotein level are prognostic factors in hepatocellular carcinoma.Q41712469
RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradationQ47073336
Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors.Q51834754
Protein expression of p53, p21WAF1, and Rb as prognostic indicators in patients with surgically treated hepatocellular carcinoma.Q53435086
Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomasQ80238304
The role of MIZ-1 in MYC-dependent tumorigenesisQ27010254
β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and TumorigenesisQ28087660
The POZ domain: a conserved protein-protein interaction motifQ28115868
RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complexQ28141074
Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoterQ28204860
Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factorsQ28205607
Repression of p15INK4b expression by Myc through association with Miz-1Q28210023
A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growthQ28910214
Cancer statistics, 2009Q29547625
p21 in cancer: intricate networks and multiple activitiesQ30436015
Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in miceQ34144845
Testing the significance of a correlation with nonnormal data: comparison of Pearson, Spearman, transformation, and resampling approachesQ34260343
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancerQ34357796
Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleocytoplasmic shuttlingQ34361027
Targeting c-Myc as a novel approach for hepatocellular carcinomaQ34391522
The cell cycle: a review of regulation, deregulation and therapeutic targets in cancerQ35157537
Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cellsQ35929384
E3 Ubiquitin Ligase RLIM Negatively Regulates c-Myc Transcriptional Activity and Restrains Cell ProliferationQ36148000
Meta-analysis of DNA methylation biomarkers in hepatocellular carcinomaQ36189699
Association of low p16INK4a and p15INK4b mRNAs expression with their CpG islands methylation with human hepatocellular carcinogenesisQ36213792
Carrot and stick: HIF-alpha engages c-Myc in hypoxic adaptationQ37054884
Gfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1.Q37083557
EGFR and SYNE2 are associated with p21 expression and SYNE2 variants predict post-operative clinical outcomes in HBV-related hepatocellular carcinomaQ37159866
Hepatocellular carcinoma: A global view.Q37589349
Aberrant DNA methylation in hepatocellular carcinoma tumor suppression (Review).Q38239671
Miz-1 promotes the proliferation of esophageal cancer cells via suppression of p21 and release of p21-arrested cyclin D1.Q38775704
RNF12 promotes p53-dependent cell growth suppression and apoptosis by targeting MDM2 for destructionQ38790178
Expression of USP22 and Survivin is an indicator of malignant behavior in hepatocellular carcinomaQ38825340
Myc-interacting zinc-finger protein 1 positively regulates Wnt signalling by protecting Dishevelled from Dapper1-mediated degradationQ38923265
Rlim, an E3 ubiquitin ligase, influences the stability of Stathmin protein in human osteosarcoma cellsQ39009753
TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4bQ39420254
RLIM interacts with Smurf2 and promotes TGF-β induced U2OS cell migration.Q39468455
RNF12 initiates X-chromosome inactivation by targeting REX1 for degradationQ39616238
Small-molecule c-Myc inhibitor, 10058-F4, inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cellsQ40198255
BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cellsQ40377462
Use of recombinant adenovirus for metabolic engineering of mammalian cells.Q40571045
P433issue47
P407language of work or nameEnglishQ1860
P921main subjectcarcinogenesisQ1637543
P304page(s)83075-83087
P577publication date2017-09-15
P1433published inOncotargetQ1573155
P1476titleRLIM suppresses hepatocellular carcinogenesis by up-regulating p15 and p21.
P478volume8

Reverse relations

Q58565593RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III-dependent transcriptioncites workP2860

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