scholarly article | Q13442814 |
P50 | author | Edward H Schuchman | Q92756224 |
P2093 | author name string | Eric L Smith | |
P2860 | cites work | Infusion of recombinant human acid sphingomyelinase into niemann-pick disease mice leads to visceral, but not neurological, correction of the pathophysiology | Q73054235 |
Tumor response to radiotherapy regulated by endothelial cell apoptosis | Q73401346 | ||
Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development | Q74105836 | ||
Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data | Q24805313 | ||
Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy | Q28140319 | ||
Human acid ceramidase is overexpressed but not mutated in prostate cancer | Q28144553 | ||
Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma | Q28240852 | ||
Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1 | Q28245694 | ||
ONCOMINE: a cancer microarray database and integrated data-mining platform | Q28255103 | ||
Self-eating and self-killing: crosstalk between autophagy and apoptosis | Q29617748 | ||
The INK4A/ARF locus: role in cell cycle control and apoptosis and implications for glioma growth | Q34283464 | ||
Raft ceramide in molecular medicine | Q35559152 | ||
Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray. | Q35791391 | ||
Biologically active sphingolipids in cancer pathogenesis and treatment | Q35852313 | ||
Role of early plasma membrane events in chemotherapy-induced cell death. | Q36153709 | ||
Ceramide-enriched membrane domains | Q36286893 | ||
Clear cell chondrosarcoma in association with niemann-pick disease | Q36674478 | ||
Retroviral-mediated transfer of the human acid sphingomyelinase cDNA: correction of the metabolic defect in cultured Niemann-Pick disease cells | Q36944261 | ||
Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells | Q40015691 | ||
Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death | Q40022622 | ||
The functional effects of acid ceramidase overexpression in prostate cancer progression and resistance to chemotherapy | Q40078162 | ||
Radioresistance of human carcinoma cells is correlated to a defect in raft membrane clustering | Q40100496 | ||
Overexpression of acid sphingomyelinase sensitizes glioma cells to chemotherapy | Q40118291 | ||
Role of acid ceramidase in resistance to FasL: therapeutic approaches based on acid ceramidase inhibitors and FasL gene therapy | Q40147066 | ||
Activation of acid sphingomyelinase by protein kinase Cdelta-mediated phosphorylation | Q40170534 | ||
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells. | Q40543801 | ||
Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells. | Q40554384 | ||
Genomic alterations in spontaneous and carcinogen-induced murine melanoma cell lines | Q40595725 | ||
Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to gamma-radiation but activation of this sequence is defective in radioresistant SQ20B cells | Q40690673 | ||
Signaling pathway for radiation-induced apoptosis in the lymphoblasts from neuronopathic (type A) and non-neuronopathic (type B) forms of Niemann-Pick disease | Q40722285 | ||
Characterization of human acid sphingomyelinase purified from the media of overexpressing Chinese hamster ovary cells | Q40805722 | ||
Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance | Q40897154 | ||
Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells | Q40984564 | ||
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. | Q42555356 | ||
An enzymatic assay for quantifying sphingomyelin in tissues and plasma from humans and mice with Niemann-Pick disease | Q43634637 | ||
A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann-Pick disease | Q44359718 | ||
Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells | Q46802157 | ||
Inhibitory activity of 6-O-angeloylprenolin from Centipeda minima on farnesyl protein transferase | Q46955200 | ||
Ceramide levels are inversely associated with malignant progression of human glial tumors. | Q48552560 | ||
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. | Q49165929 | ||
pH distribution in human tumors. | Q51822491 | ||
CD95 Signaling via Ceramide-rich Membrane Rafts | Q57371964 | ||
P433 | issue | 9 | |
P921 | main subject | overexpression | Q61643320 |
P304 | page(s) | 1565-1571 | |
P577 | publication date | 2008-07-15 | |
P1433 | published in | Molecular Therapy | Q15762400 |
P1476 | title | Acid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in vitro and in vivo. | |
P478 | volume | 16 |
Q39837844 | A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells |
Q37640501 | Acid sphingomyelinase, cell membranes and human disease: lessons from Niemann-Pick disease |
Q104795150 | Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis |
Q34086900 | Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis |
Q38082724 | Active autophagy in the tumor microenvironment: A novel mechanism for cancer metastasis |
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Q37357098 | Altering the sphingolipid acyl chain composition prevents LPS/GLN-mediated hepatic failure in mice by disrupting TNFR1 internalization |
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