Acid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in vitro and in vivo.

scientific article published on 15 July 2008

Acid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in vitro and in vivo. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MT.2008.145
P698PubMed publication ID18628757
P5875ResearchGate publication ID51403653

P50authorEdward H SchuchmanQ92756224
P2093author name stringEric L Smith
P2860cites workInfusion of recombinant human acid sphingomyelinase into niemann-pick disease mice leads to visceral, but not neurological, correction of the pathophysiologyQ73054235
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Overexpression of acid sphingomyelinase sensitizes glioma cells to chemotherapyQ40118291
Role of acid ceramidase in resistance to FasL: therapeutic approaches based on acid ceramidase inhibitors and FasL gene therapyQ40147066
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Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to gamma-radiation but activation of this sequence is defective in radioresistant SQ20B cellsQ40690673
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Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistanceQ40897154
Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cellsQ40984564
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.Q42555356
An enzymatic assay for quantifying sphingomyelin in tissues and plasma from humans and mice with Niemann-Pick diseaseQ43634637
A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann-Pick diseaseQ44359718
Lipid mediators of autophagy in stress-induced premature senescence of endothelial cellsQ46802157
Inhibitory activity of 6-O-angeloylprenolin from Centipeda minima on farnesyl protein transferaseQ46955200
Ceramide levels are inversely associated with malignant progression of human glial tumors.Q48552560
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice.Q49165929
pH distribution in human tumors.Q51822491
CD95 Signaling via Ceramide-rich Membrane RaftsQ57371964
P433issue9
P921main subjectoverexpressionQ61643320
P304page(s)1565-1571
P577publication date2008-07-15
P1433published inMolecular TherapyQ15762400
P1476titleAcid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in vitro and in vivo.
P478volume16

Reverse relations

cites work (P2860)
Q39837844A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells
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