| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/1529-0131(199809)41:9<1632::AID-ART14>3.0.CO;2-A |
| P698 | PubMed publication ID | 9751096 |
| P2093 | author name string | Hashimoto S | |
| Ochs RL | |||
| Lotz M | |||
| Komiya S | |||
| P433 | issue | 9 | |
| P921 | main subject | osteoarthritis | Q62736 |
| cartilage | Q502730 | ||
| apoptotic process | Q14599311 | ||
| P304 | page(s) | 1632-1638 | |
| P577 | publication date | 1998-09-01 | |
| P1433 | published in | Arthritis & Rheumatology | Q4797636 |
| P1476 | title | Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis. | |
| P478 | volume | 41 |
| Q36159219 | 17β-Oestradiol inhibits doxorubicin-induced apoptosis via block of the volume-sensitive Cl(-) current in rabbit articular chondrocytes |
| Q41395349 | 4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase |
| Q51192373 | A Dual Role of Upper Zone of Growth Plate and Cartilage Matrix-Associated Protein in Human and Mouse Osteoarthritic Cartilage: Inhibition of Aggrecanases and Promotion of Bone Turnover. |
| Q51608189 | A new role for chondrocytes as non-professional phagocytes. An in vitro study. |
| Q34102868 | ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis |
| Q37353085 | Advanced osteoarthritis in humans is associated with altered collagen VI expression and upregulation of ER-stress markers Grp78 and bag-1. |
| Q37136657 | Age-related carbonylation of fibrocartilage structural proteins drives tissue degenerative modification |
| Q45989449 | Age-related histologic and biochemical changes in auricular and septal cartilage. |
| Q36194020 | Alpha B-Crystallin Protects Rat Articular Chondrocytes against Casein Kinase II Inhibition-Induced Apoptosis |
| Q41833129 | Altered Chondrocyte Apoptosis Status in Developmental Hip Dysplasia in Rabbits |
| Q46293661 | An atypical degenerative osteoarthropathy in Hyp mice is characterized by a loss in the mineralized zone of articular cartilage |
| Q41539024 | An optical probe for detecting chondrocyte apoptosis in response to mechanical injury. |
| Q38817800 | An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis |
| Q43709161 | Anti-Fas-induced apoptosis in chondrocytes reduced by hyaluronan: evidence for CD44 and CD54 (intercellular adhesion molecule 1) invovement |
| Q35193756 | Apoptosis and the loss of chondrocyte survival signals contribute to articular cartilage degradation in osteoarthritis |
| Q35549052 | Apoptosis in normal and osteoarthritic human articular cartilage |
| Q34074029 | Apoptosis in rheumatic diseases |
| Q53480157 | Apoptosis in the traumatic and degenerative tears of human meniscus. |
| Q30992895 | Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritis human articular knee cartilage: a study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee |
| Q50498747 | Apoptotic chondrocyte death in cell-matrix biocomposites used in autologous chondrocyte transplantation. |
| Q24805351 | Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis |
| Q34637361 | Articular cartilage calcification and matrix vesicles |
| Q44466389 | Articular chondrocyte apoptosis in equine osteoarthritis |
| Q74509531 | Articular chondrocytes from animals with a dermatan sulfate storage disease undergo a high rate of apoptosis and release nitric oxide and inflammatory cytokines: a possible mechanism underlying degenerative joint disease in the mucopolysaccharidoses |
| Q42286696 | Assessment of apoptosis and MMP-1, MMP-3 and TIMP-2 expression in tibial hyaline cartilage after viable medial meniscus transplantation in the rabbit |
| Q47728669 | Autologous solution protects bovine cartilage explants from IL-1α- and TNFα-induced cartilage degradation |
| Q35140949 | Automated generation of tissue-specific three-dimensional finite element meshes containing ellipsoidal cellular inclusions |
| Q58606829 | Autophagy protects against redox-active trace metal-induced cell death in rabbit synovial fibroblasts through TLR4 activation |
| Q64100869 | Bax Targeted by miR-29a Regulates Chondrocyte Apoptosis in Osteoarthritis |
| Q104461446 | Beneficial effects of Vigna angularis extract in osteoporosis and osteoarthritis |
| Q58576405 | Bioinformatics analysis to identify key genes and pathways influencing synovial inflammation in osteoarthritis |
| Q41836157 | Biological Effects of Phosphocitrate on Osteoarthritic Articular Chondrocytes |
| Q41810542 | Biological activities of phosphocitrate: a potential meniscal protective agent |
| Q34225355 | Biological aspects of early osteoarthritis |
| Q35899103 | Biological effects of the plant-derived polyphenol resveratrol in human articular cartilage and chondrosarcoma cells |
| Q34786993 | Blocking vascular endothelial growth factor with soluble Flt-1 improves the chondrogenic potential of mouse skeletal muscle-derived stem cells |
| Q36369257 | Bushen Zhuangjin decoction inhibits TM-induced chondrocyte apoptosis mediated by endoplasmic reticulum stress |
| Q42420906 | CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase |
| Q89944396 | COL2A1 and Caspase-3 as Promising Biomarkers for Osteoarthritis Prognosis in an Equus asinus Model |
| Q45049380 | Ca2+-Dependent Endoplasmic Reticulum Stress Regulates Mechanical Stress-Mediated Cartilage Thinning |
| Q35026754 | Cannabinoid receptor CB2 is involved in tetrahydrocannabinol-induced anti-inflammation against lipopolysaccharide in MG-63 cells |
| Q37761086 | Cartilage cell clusters. |
| Q36934659 | Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1. |
| Q55067437 | Celecoxib Combined with Diacerein Effectively Alleviates Osteoarthritis in Rats via Regulating JNK and p38MAPK Signaling Pathways. |
| Q28067045 | Cell Death in Chondrocytes, Osteoblasts, and Osteocytes |
| Q39561182 | Cellular and molecular mechanisms of anti-inflammatory effect of Aflapin: a novel Boswellia serrata extract. |
| Q48691321 | Chondrocyte apoptosis in response to dislocation of the hip in the rat model |
| Q44680714 | Chondrocyte apoptosis induced by collagen degradation: inhibition by caspase inhibitors and IGF-1. |
| Q37868776 | Chondrocyte apoptosis: a cause or consequence of osteoarthritis? |
| Q36975916 | Chondrocyte apoptosis: implications for osteochondral allograft transplantation |
| Q35679918 | Chondrocyte clusters adjacent to sites of cartilage degeneration have characteristics of progenitor cells. |
| Q35553649 | Chondrocyte number and proteoglycan synthesis in the aging and osteoarthritic human articular cartilage |
| Q36623476 | Cilostazol induces cellular senescence and confers resistance to etoposide-induced apoptosis in articular chondrocytes |
| Q37581675 | Comparative analysis of signaling pathways in peripheral blood from patients with Kashin-Beck disease and osteoarthritis |
| Q35097443 | Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders |
| Q43716640 | Corticosteroids alter the differentiated phenotype of articular chondrocytes |
| Q42732233 | Curcumin synergizes with resveratrol to stimulate the MAPK signaling pathway in human articular chondrocytes in vitro |
| Q41947962 | Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro |
| Q40123028 | DUSP19, a downstream effector of leptin, inhibits chondrocyte apoptosis via dephosphorylating JNK during osteoarthritis pathogenesis |
| Q34048178 | Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis |
| Q33895200 | Downregulation of protein kinase CK2 activity facilitates tumor necrosis factor-α-mediated chondrocyte death through apoptosis and autophagy |
| Q43049067 | Effect of nitric oxide on mitochondrial respiratory activity of human articular chondrocytes. |
| Q83425376 | Effect of resveratrol on cartilage protection and apoptosis inhibition in experimental osteoarthritis of rabbit |
| Q38726648 | Effects of UCP4 on the Proliferation and Apoptosis of Chondrocytes: Its Possible Involvement and Regulation in Osteoarthritis. |
| Q36024475 | Effects of aging on articular cartilage homeostasis |
| Q46500387 | Effects of different hyaluronic acid products on synovial fluid NO levels in knee osteoarthritis |
| Q37661071 | Effects of flurbiprofen and tiaprofenic Acid on oxidative stress markers in osteoarthritis: A prospective, randomized, open-label, active- and placebo-controlled trial |
| Q79443313 | Effects of hyaluronan on nitric oxide levels and superoxide dismutase activities in synovial fluid in knee osteoarthritis |
| Q31120838 | Emerging techniques for the discovery and validation of therapeutic targets for skeletal diseases |
| Q50481258 | Enhanced production of MMP-1, MMP-3, MMP-13, and RANTES by interaction of chondrocytes with autologous T cells. |
| Q37974499 | Etiology of osteoarthritis: genetics and synovial joint development |
| Q57813369 | Evaluation of structural, mechanical, and cellular behavior of electrospun poly-3-hydroxybutyrate scaffolds loaded with glucosamine sulfate to develop cartilage tissue engineering |
| Q46149080 | Extracellular vesicles in cartilage homeostasis and osteoarthritis |
| Q36763014 | Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop |
| Q46281605 | Glutamate inhibits chondral mineralization through apoptotic cell death mediated by retrograde operation of the cystine/glutamate antiporter. |
| Q24797551 | Higher susceptibility to Fas ligand induced apoptosis and altered modulation of cell death by tumor necrosis factor-alpha in periarticular tenocytes from patients with knee joint osteoarthritis |
| Q56957220 | Histomorphologic and histomorphometric characteristics of zygapophyseal joint remodeling in ankylosing spondylitis |
| Q43193622 | Hyaluronic acid inhibits nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes in vitro |
| Q35754688 | Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction |
| Q43239543 | Hypoxic resistance to articular chondrocyte apoptosis--a possible mechanism of maintaining homeostasis of normal articular cartilage |
| Q42663802 | Increased chondrocyte apoptosis is associated with progression of osteoarthritis in spontaneous Guinea pig models of the disease. |
| Q34164358 | Increased chondrocyte death after steroid and local anesthetic combination. |
| Q44572438 | Influence of pro-inflammatory (IL-1 alpha, IL-6, TNF-alpha, IFN-gamma) and anti-inflammatory (IL-4) cytokines on chondrocyte function |
| Q44733630 | Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression |
| Q44586253 | Inhibition of chondrocyte apoptosis in vivo following acute osteochondral injury |
| Q34673887 | Initial responses of articular tissues in a murine high-fat diet-induced osteoarthritis model: pivotal role of the IPFP as a cytokine fountain |
| Q28079781 | Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis |
| Q38294262 | Insulin-like growth factor I regulates apoptosis in condylar cartilage |
| Q28343531 | Interleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa |
| Q40443689 | Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner |
| Q24804189 | Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action |
| Q43803960 | Intracellular accumulation of advanced glycation end products induces apoptosis via endoplasmic reticulum stress in chondrocytes |
| Q34346264 | Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair |
| Q89731175 | LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes |
| Q47632836 | Lidocaine induces ROCK-dependent membrane blebbing and subsequent cell death in rabbit articular chondrocytes |
| Q64969427 | Loganin Attenuates Osteoarthritis in Rats by Inhibiting IL-1β-Induced Catabolism and Apoptosis in Chondrocytes Via Regulation of Phosphatidylinositol 3-Kinases (PI3K)/Akt. |
| Q47144390 | Long noncoding RNAs: a new regulatory code in osteoarthritis |
| Q51392424 | Long-term oral administration of glucosamine or chondroitin sulfate reduces destruction of cartilage and up-regulation of MMP-3 mRNA in a model of spontaneous osteoarthritis in Hartley guinea pigs. |
| Q35126667 | Matrix vesicles and calcification |
| Q41578159 | Mechanical impact induces cartilage degradation via mitogen activated protein kinases. |
| Q80543447 | Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis--structure, chaos and senescence |
| Q98464903 | Metformin Mitigates Cartilage Degradation by Activating AMPK/SIRT1-Mediated Autophagy in a Mouse Osteoarthritis Model |
| Q47119870 | MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN. |
| Q36983759 | MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis |
| Q64942867 | Microscale frictional strains determine chondrocyte fate in loaded cartilage. |
| Q44359278 | Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes |
| Q36832831 | Modulation of Apoptosis and Differentiation by the Treatment of Sulfasalazine in Rabbit Articular Chondrocytes |
| Q35802340 | Mycoplasma synoviae induces upregulation of apoptotic genes, secretion of nitric oxide and appearance of an apoptotic phenotype in infected chicken chondrocytes |
| Q91994891 | NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction |
| Q34108748 | New developments in the pathogenesis of articular cartilage calcification |
| Q41696724 | Nitric oxide production and apoptosis in cells of the meniscus during experimental osteoarthritis |
| Q36249227 | Nitric oxide-associated chondrocyte apoptosis in trauma patients after high-energy lower extremity intra-articular fractures |
| Q44317021 | Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity |
| Q91012315 | Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes |
| Q98784885 | Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation |
| Q35758917 | Osteopontin inhibits HIF-2α mRNA expression in osteoarthritic chondrocytes |
| Q64943174 | P2X7 ionotropic receptor is functionally expressed in rabbit articular chondrocytes and mediates extracellular ATP cytotoxicity. |
| Q46594882 | Pathogenesis of osteoarthritis: chondrocyte replicative senescence or apoptosis? |
| Q89920243 | Pathomechanisms of Posttraumatic Osteoarthritis: Chondrocyte Behavior and Fate in a Precarious Environment |
| Q37406721 | Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes |
| Q36128347 | Pleiotropic Functions of High Fat Diet in the Etiology of Osteoarthritis |
| Q37721704 | Post-Traumatic Osteoarthritis in Mice Following Mechanical Injury to the Synovial Joint |
| Q86069230 | Potential of Raloxifene in reversing osteoarthritis-like alterations in rat chondrocytes: an in vitro model study |
| Q36709565 | Preventing friction-induced chondrocyte apoptosis: comparison of human synovial fluid and hylan G-F 20 |
| Q28729755 | Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model |
| Q37123943 | Prolactin promotes cartilage survival and attenuates inflammation in inflammatory arthritis. |
| Q92577648 | Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis |
| Q33580825 | Protective effect of resveratrol against IL-1β-induced inflammatory response on human osteoarthritic chondrocytes partly via the TLR4/MyD88/NF-κB signaling pathway: an "in vitro study" |
| Q27027425 | Proteoglycan metabolism, cell death and Kashin-Beck disease |
| Q42802558 | Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction. |
| Q47228976 | Recovery of articular cartilage metabolism following thermal stress is facilitated by IGF-1 and JNK inhibitor |
| Q43683241 | Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes |
| Q51356935 | Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63. |
| Q48375231 | Regulation of chondrocyte functions by transient receptor potential cation channel V6 in osteoarthritis. |
| Q40227620 | Resveratrol inhibits IL-1 beta-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro |
| Q37574870 | Resveratrol regulates type II collagen and COX-2 expression via the ERK, p38 and Akt signaling pathways in rabbit articular chondrocytes |
| Q38526198 | Role of c-Maf in Chondrocyte Differentiation: A Review |
| Q44623692 | Role of nitric oxide, reactive oxygen species, and p38 MAP kinase in the regulation of human chondrocyte apoptosis |
| Q38836896 | Sam68 Promotes NF-κB Activation and Apoptosis Signaling in Articular Chondrocytes during Osteoarthritis |
| Q35791362 | Short-term exposure of cartilage to blood results in chondrocyte apoptosis |
| Q84627089 | Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro |
| Q39176961 | Single-dose local anesthetics exhibit a type-, dose-, and time-dependent chondrotoxic effect on chondrocytes and cartilage: a systematic review of the current literature |
| Q28211978 | Site-specific analysis of gene expression in early osteoarthritis using the Pond-Nuki model in dogs |
| Q41863154 | Sodium fluoride induces apoptosis through the downregulation of hypoxia-inducible factor-1α in primary cultured rat chondrocytes |
| Q34613489 | Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis |
| Q51617184 | Synovial apoptosis in temporomandibular joint disc displacement without reduction. |
| Q87921032 | Taurine alleviates endoplasmic reticulum stress in the chondrocytes from patients with osteoarthritis |
| Q35558497 | Terminal differentiation is not a major determinant for the success of stem cell therapy - cross-talk between muscle-derived stem cells and host cells |
| Q42916722 | The COX-2 selective blocker etodolac inhibits TNFα-induced apoptosis in isolated rabbit articular chondrocytes |
| Q64273550 | The Link Between Inflammaging and Degenerative Joint Diseases |
| Q48338346 | The clustering and morphology of chondrocytes in normal and mildly degenerate human femoral head cartilage studied by confocal laser scanning microscopy. |
| Q53199147 | The effect of therapeutic ultrasound to apoptosis of chondrocyte and caspase-3 and caspase-8 expression in rabbit surgery-induced model of knee osteoarthritis. |
| Q46813182 | The effects of different decalcification protocols on TUNEL and general cartilage staining |
| Q78733352 | The fate of soft callus chondrocytes during long bone fracture repair |
| Q37685302 | The involvement and possible mechanism of NR4A1 in chondrocyte apoptosis during osteoarthritis |
| Q61808817 | The morphology and histology study on rabbit degenerated medial meniscus after posterior cruciate ligament rupture |
| Q42914772 | The properties of chondrocyte membrane reservoirs and their role in impact-induced cell death. |
| Q42134988 | The protective effect of sodium hyaluronate on the cartilage of rabbit osteoarthritis by inhibiting peroxisome proliferator-activated receptor-gamma messenger RNA expression |
| Q37825773 | The role of mitochondria in osteoarthritis |
| Q60958885 | Theaflavins prevent cartilage degeneration via AKT/FOXO3 signaling in vitro |
| Q73811973 | Time, stress, and location dependent chondrocyte death and collagen damage in cyclically loaded articular cartilage |
| Q37342293 | Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation |
| Q52539927 | Tumor necrosis factor-alpha induced DNA cleavage in human articular chondrocytes may involve multiple endonucleolytic activities during apoptosis. |
| Q74604121 | Tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in human articular chondrocytes in vitro |
| Q34963140 | Type II collagen degradation and its regulation in articular cartilage in osteoarthritis |
| Q43103880 | Ultrastructural quantification of cell death after injurious compression of bovine calf articular cartilage |
| Q53125268 | Unfolding of membrane ruffles of in situ chondrocytes under compressive loads. |
| Q46836252 | Unusual digital articular destructions after radio-synovectomy and cortisone injection therapy for Bouchard arthrosis |
| Q84069956 | Variations in chondrocyte apoptosis may explain the increased prevalence of osteoarthritis in some joints |
| Q35117279 | What type of cartilage repair are we attempting to attain? |
| Q34029908 | Withaferin A-caused production of intracellular reactive oxygen species modulates apoptosis via PI3K/Akt and JNKinase in rabbit articular chondrocytes |
| Q54964471 | Zhuangguguanjie formulation protects articular cartilage from degeneration in joint instability-induced murine knee osteoarthritis. |
| Q45733251 | c-Jun N-terminal kinase - c-Jun pathway transactivates Bim to promote osteoarthritis |
| Q36245802 | miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4. |
| Q54382930 | p38 kinase-dependent and -independent Inhibition of protein kinase C zeta and -alpha regulates nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes. |
Search more.