ES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L.

scientific article published in July 2009

ES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/STEM.86
P932PMC publication ID6338332
P698PubMed publication ID19544450
P5875ResearchGate publication ID26309070

P2093author name stringTheodore P Rasmussen
Craig E Nelson
Dominic J Ambrosi
Evan R Barry
Winfried Krueger
Eric Veilleux
Caroline M Jakuba
P2860cites workHistone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachmentQ24321876
Induction of the interferon response by siRNA is cell type- and duplex length-dependentQ24544339
Histone modifications defining active genes persist after transcriptional and mitotic inactivationQ24557457
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cellsQ24655388
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repairQ24669691
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein associationQ24675122
A bivalent chromatin structure marks key developmental genes in embryonic stem cellsQ27860977
The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylationQ27930884
hDOT1L links histone methylation to leukemogenesisQ27935809
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.Q27939003
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaksQ28291639
The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structureQ28473586
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domainQ28609769
Active genes are tri-methylated at K4 of histone H3Q29547668
Histone H3 lysine 4 methylation patterns in higher eukaryotic genesQ29614678
Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2.Q30479488
Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.Q33905153
A shift from reversible to irreversible X inactivation is triggered during ES cell differentiationQ33908327
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.Q34485045
Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegationQ34762156
Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1LQ35586594
Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instabilityQ35828731
Dynamic relocalization of histone MacroH2A1 from centrosomes to inactive X chromosomes during X inactivationQ36328635
GOEAST: a web-based software toolkit for Gene Ontology enrichment analysisQ36749336
Developmentally-poised chromatin of embryonic stem cellsQ36992175
Genome-wide reprogramming in hybrids of somatic cells and embryonic stem cellsQ40175811
Dynamic changes in histone H3 lysine 9 methylations: identification of a mitosis-specific function for dynamic methylation in chromosome congression and segregationQ40337035
Profile of histone lysine methylation across transcribed mammalian chromatinQ41077260
Early detection of apoptosis using a fluorescent conjugate of annexin V.Q41090921
Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmissionQ41113992
Chromosome number variation in three mouse embryonic stem cell lines during cultureQ41335515
Dynamic regulation of histone H3 methylated at lysine 79 within a tissue-specific chromatin domain.Q44327227
Changes in H3K79 methylation during preimplantation development in miceQ46899764
A simple method for forming embryoid body from mouse embryonic stem cells.Q51335529
Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells.Q51980445
Induction of an interferon response by RNAi vectors in mammalian cellsQ58235166
Selective di- or trimethylation of histone H3 lysine 76 by two DOT1 homologs is important for cell cycle regulation in Trypanosoma bruceiQ61485153
The chromosome make-up of mouse embryonic stem cells is predictive of somatic and germ cell chimaerismQ73760073
P433issue7
P921main subjectembryonic stem cellQ1151519
P304page(s)1538-1547
P577publication date2009-07-01
P1433published inStem CellsQ15724411
P1476titleES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L
P478volume27