Design and Synthesis of Some Novel Fluorobenzimidazoles Substituted with Structural Motifs Present in Physiologically Active Natural Products for Antitubercular Activity.

scientific article published in January 2017

Design and Synthesis of Some Novel Fluorobenzimidazoles Substituted with Structural Motifs Present in Physiologically Active Natural Products for Antitubercular Activity. is …
instance of (P31):
scholarly articleQ13442814

External links are
P932PMC publication ID5610749
P698PubMed publication ID29201084

P2093author name stringKishore Bhat
Bangalore Nandha
Laxmivenkatesh Gurachar Nargund
Shachindra Laxmivenkatesh Nargund
P2860cites workDesign, synthesis and biological evaluation of some novel benzimidazole derivatives for their potential anticonvulsant activityQ42956958
Synthesis, vasorelaxant activity and antihypertensive effect of benzo[d]imidazole derivativesQ43069690
In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivativesQ43172998
SAR study of clubbed [1,2,4]-triazolyl with fluorobenzimidazoles as antimicrobial and antituberculosis agentsQ43974164
Synthesis and preliminary evaluation of benzimidazole derivatives as antimicrobial agents.Q43991349
Synthesis and evaluation of in vitro anti-microbial and anti-tubercular activity of 2-styryl benzimidazoles.Q45961608
Synthesis and evaluation of a novel series of pseudo-cinnamic derivatives as antituberculosis agentsQ46197312
Clubbed [1,2,3] triazoles by fluorine benzimidazole: a novel approach to H37Rv inhibitors as a potential treatment for tuberculosis.Q46310260
Comparative studies on conventional and microwave synthesis of some benzimidazole, benzothiazole and indole derivatives and testing on inhibition of hyaluronidase.Q46607098
Synthesis and antioxidant properties of novel N-methyl-1,3,4-thiadiazol-2-amine and 4-methyl-2H-1,2,4-triazole-3(4H)-thione derivatives of benzimidazole classQ46705117
Synthesis and antiprotozoal activity of some 2-(trifluoromethyl)-1H-benzimidazole bioisosteresQ46783558
Inhibition of bacterial cell division protein FtsZ by cinnamaldehyde.Q53537364
Identification of cell cycle regulators in Mycobacterium tuberculosis by inhibition of septum formation and global transcriptional analysisQ61787756
Quinoline alkaloids from Lunasia amara inhibit Mycobacterium tuberculosis H37Rv in vitroQ63363590
Synthesis of benzimidazole derivatives as antiallergic agents with 5-lipoxygenase inhibiting actionQ73289729
Design, synthesis and antitumor cytotoxicity of novel bis-benzimidazolesQ73493378
Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathwayQ95437896
Activity against Mycobacterium tuberculosis of alkaloid constituents of Angostura bark, Galipea officinalisQ28374968
Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium aviumQ28378889
Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assayQ28379335
Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliabilityQ29617252
Design, synthesis and evaluation of novel 2,5,6-trisubstituted benzimidazoles targeting FtsZ as antitubercular agents.Q33711825
Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agentsQ33761632
In vitro-in vivo activity relationship of substituted benzimidazole cell division inhibitors with activity against Mycobacterium tuberculosisQ33797084
Antimycobacterial natural productsQ35618520
New perspectives on natural products in TB drug researchQ36294148
Natural product growth inhibitors of Mycobacterium tuberculosis.Q36772385
SAR studies on trisubstituted benzimidazoles as inhibitors of Mtb FtsZ for the development of novel antitubercular agentsQ37600601
Simple Synthesis and Biological Evaluation of Some Benzimidazoles Using Sodium Hexafluroaluminate, Na 3 AlF 6 , as an Efficient CatalystQ37700648
Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages.Q39207272
Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitorsQ39513979
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitorsQ39967417
Synthesis, antiprotozoal and anticancer activity of substituted 2-trifluoromethyl- and 2-pentafluoroethylbenzimidazolesQ40661081
Design and Synthesis of New Benzimidazole and Pyrimidine Derivatives as α-glucosidase InhibitorQ41836177
Benzimidazole-based compounds kill Mycobacterium tuberculosisQ42227583
Design, synthesis and antitubercular evaluation of novel series of N-[4-(piperazin-1-yl)phenyl]cinnamamide derivativesQ42706843
Design, synthesis, and biological evaluation of new cinnamic derivatives as antituberculosis agentsQ42751415
P433issue3
P921main subjectnatural productQ901227
P304page(s)929-942
P577publication date2017-01-01
P1433published inIranian journal of pharmaceutical researchQ20183787
P1476titleDesign and Synthesis of Some Novel Fluorobenzimidazoles Substituted with Structural Motifs Present in Physiologically Active Natural Products for Antitubercular Activity.
P478volume16

Reverse relations

Q57928149Investigation of the anti-TB potential of selected propolis constituents using a molecular docking approachcites workP2860

Search more.