Building structure-activity insights through patent mining.

scientific article

Building structure-activity insights through patent mining. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4155/PPA.12.60
P698PubMed publication ID24236924

P2093author name stringJeffrey A Pfefferkorn
Angel Guzman-Perez
Kevin J Filipski
Meihua Tu
P2860cites workDescription of several chemical structure file formats used by computer programs developed at Molecular Design LimitedQ27783587
Mining chemical information from open patentsQ28743320
Chemography: the art of navigating in chemical space.Q30986108
Patent data mining: a tool for accelerating HIV vaccine innovationQ33874576
Assessing the potential of glucokinase activators in diabetes therapyQ34976240
Knowledge discovery in biology and biotechnology texts: a review of techniques, evaluation strategies, and applicationsQ36184644
Mining chemical structural information from the drug literatureQ36396530
Glucokinase activators for diabetes therapy: May 2010 status reportQ36783849
Diabetes area participation analysis: a review of companies and targets described in the 2008 - 2010 patent literatureQ37810292
Targeting the DFG-in kinase conformation: a new trend emerging from a patent analysisQ37859008
Competitive intelligence and patent analysis in drug discoveryQ38225075
Piragliatin (RO4389620), a novel glucokinase activator, lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus: a mechanistic studyQ42925831
Allosteric activators of glucokinase: potential role in diabetes therapyQ44517691
Exploiting structural information in patent specifications for key compound predictionQ45224632
SAR, pharmacokinetics, safety, and efficacy of glucokinase activating 2-(4-sulfonylphenyl)-N-thiazol-2-ylacetamides: discovery of PSN-GK1.Q46512394
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus.Q51363512
Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients.Q54496427
Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs.Q54557986
P433issue5
P304page(s)545-554
P577publication date2012-11-01
P1433published inPharmaceutical patent analystQ26867046
P1476titleBuilding structure-activity insights through patent mining.
P478volume1

Search more.