Signal transduction involved in CTGF-induced production of chemokines in mesangial cells

scientific article published in August 2008

Signal transduction involved in CTGF-induced production of chemokines in mesangial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1080/08977190802227828
P698PubMed publication ID19378419

P2093author name stringChao Lu
Ling Dong
Sheng-Hua Wu
Zi-Qing Chen
P2860cites workActivation of nuclear factor kappa B (NF-kappaB) by connective tissue growth factor (CCN2) is involved in sustaining the survival of primary rat hepatic stellate cellsQ24815319
The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor is a receptor for connective tissue growth factorQ28214235
Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkAQ28298502
A new class of membrane-bound chemokine with a CX3C motifQ28303204
Tumor necrosis factor-alpha stimulates fractalkine production by mesangial cells and regulates monocyte transmigration: down-regulation by cAMPQ28574982
Connective tissue growth factor is overexpressed in complicated atherosclerotic plaques and induces mononuclear cell chemotaxis in vitroQ33212781
Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycansQ33902687
Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosisQ34050059
Connective tissue growth factor and renal diseases: some answers, more questionsQ35748402
Structural and functional properties of CCN proteinsQ36053014
Differential activation of NF-kappa B, AP-1, and C/EBP in endotoxin-tolerant rats: mechanisms for in vivo regulation of glomerular RANTES/CCL5 expressionQ38353821
TGF-beta1 induces IL-8 and MCP-1 through a connective tissue growth factor-independent pathwayQ40365592
Lipoxin A4 inhibits proliferation of human lung fibroblasts induced by connective tissue growth factorQ40377568
Protein overload induces fractalkine upregulation in proximal tubular cells through nuclear factor kappaB- and p38 mitogen-activated protein kinase-dependent pathwaysQ40630754
Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factorQ40656344
Demonstration of receptors specific for connective tissue growth factor on a human chondrocytic cell line (HCS-2/8).Q41029521
Recombinant fish neurotrophin-6 is a heparin-binding glycoprotein: implications for a role in axonal guidanceQ41108097
Cloning and expression of a novel neurotrophin, NT-7, from carpQ42693393
Characterization of cell-associated and soluble forms of connective tissue growth factor (CTGF) produced by fibroblast cells in vitroQ42830647
Site A of the MCP-1 distal regulatory region functions as a transcriptional modulator through the transcription factor NF1.Q42832244
Akt serine threonine kinase regulates platelet-derived growth factor-induced DNA synthesis in glomerular mesangial cells: regulation of c-fos AND p27(kip1) gene expressionQ43686297
Hemozoin induces macrophage chemokine expression through oxidative stress-dependent and -independent mechanismsQ43990694
The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells.Q44129438
Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2.Q44438488
The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.Q44449820
Gene therapy via blockade of monocyte chemoattractant protein-1 for renal fibrosis.Q45873944
Lipoxin A4 inhibits TNF-alpha-induced production of interleukins and proliferation of rat mesangial cellsQ46545463
Connective tissue growth factor (CCN2) in rat pancreatic stellate cell function: integrin alpha5beta1 as a novel CCN2 receptorQ46687832
CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblastsQ46949378
Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10,000 forms of connective tissue growth factorQ48046112
CCN2 is necessary for the function of mouse embryonic fibroblasts.Q54561247
P433issue4
P921main subjectmesangial cellQ3331086
P304page(s)192-200
P577publication date2008-08-01
P1433published inGrowth Factors JournalQ5611728
P1476titleSignal transduction involved in CTGF-induced production of chemokines in mesangial cells
P478volume26

Reverse relations

cites work (P2860)
Q35536426BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses
Q26779818CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma?
Q34997831Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice
Q33811918Connective tissue growth factor promotes fibrosis downstream of TGFbeta and IL-6 in chronic cardiac allograft rejection.
Q37392107Connective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?
Q43763309Fell-Muir lecture: Connective tissue growth factor (CCN2) -- a pernicious and pleiotropic player in the development of kidney fibrosis
Q54282848Glomerular expression of fractalkine is induced by polyinosinic-polycytidylic acid in human mesangial cells: possible involvement of fractalkine after viral infection.
Q42287848Hyperglycemia causes renal cell damage via CCN2-induced activation of the TrkA receptor: implications for diabetic nephropathy.
Q89578732IL-20 in Acute Kidney Injury: Role in Pathogenesis and Potential as a Therapeutic Target
Q35221297Regulation of fibronectin-EDA through CTGF domain-specific interactions with TGFβ2 and its receptor TGFβRII
Q28254386Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
Q42876722The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells.
Q37683183The Small Tellurium Compound AS101 Ameliorates Rat Crescentic Glomerulonephritis: Association with Inhibition of Macrophage Caspase-1 Activity via Very Late Antigen-4 Inactivation
Q42700805The sirtuin 6 prevents angiotensin II-mediated myocardial fibrosis and injury by targeting AMPK-ACE2 signaling
Q53452072Thrombopoietin Signaling Pathway Regulates Hepatocyte Activation in Rat Liver Regeneration.
Q38381157WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts.

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