How winner cells cause the demise of loser cells: cell competition causes apoptosis of suboptimal cells: their dregs are removed by hemocytes, thus preserving tissue homeostasis

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How winner cells cause the demise of loser cells: cell competition causes apoptosis of suboptimal cells: their dregs are removed by hemocytes, thus preserving tissue homeostasis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/BIES.201200156
P698PubMed publication ID23382037
P5875ResearchGate publication ID235401976

P50authorEduardo Moreno LampayaQ107281316
P2093author name stringFidel-Nicolás Lolo
Sergio Casas Tintó
P2860cites workCancer-related inflammationQ27860907
Macrophage plasticity and polarization: in vivo veritasQ29547620
The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancyQ30494710
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dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cellsQ33707393
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In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.Q34428953
A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis.Q35001595
The expression of SPARC in human tumors is consistent with its role during cell competition.Q35015135
Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesisQ35060075
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scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in DrosophilaQ37367551
Cell competition and its implications for development and cancerQ37478763
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The society of our "out of Africa" ancestors (I): The migrant warriors that colonized the worldQ39267969
Loss of Scribble causes cell competition in mammalian cells.Q39411256
Drosophila SPARC is a self-protective signal expressed by loser cells during cell competition.Q39643477
Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells.Q41202883
Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of YapQ42023045
Flower forms an extracellular code that reveals the fitness of a cell to its neighbors in DrosophilaQ42474244
Extrusion of cells with inappropriate Dpp signaling from Drosophila wing disc epitheliaQ42475729
A non-cell-autonomous tumor suppressor role for Stat in eliminating oncogenic scribble cells.Q42515031
An innate immune response of blood cells to tumors and tissue damage in DrosophilaQ42614126
Minutes: Mutants of Drosophila autonomously affecting cell division rateQ44889355
Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila.Q46302676
Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wingQ46387460
Engulfment is required for cell competitionQ47070024
Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development.Q47070908
Drosophila myc regulates organ size by inducing cell competitionQ47071644
dMyc transforms cells into super-competitorsQ47072112
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.Q47072330
Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila.Q47072359
An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth controlQ47072375
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.Q50754378
Cellular degeneration in the production of some mutant phenotypes in Drosophila melanogaster.Q52486643
Cell competition time line: winners kill losers, which are extruded and engulfed by hemocytes.Q52743805
P433issue4
P407language of work or nameEnglishQ1860
P921main subjecttissue homeostasisQ14873636
P304page(s)348-353
P577publication date2013-02-04
P1433published inBioEssaysQ4914614
P1476titleHow winner cells cause the demise of loser cells: cell competition causes apoptosis of suboptimal cells: their dregs are removed by hemocytes, thus preserving tissue homeostasis
P478volume35

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cites work (P2860)
Q47072184Active JNK-dependent secretion of Drosophila Tyrosyl-tRNA synthetase by loser cells recruits haemocytes during cell competition
Q42863365Apoptosis in Living Animals Is Assisted by Scavenger Cells and Thus May Not Mainly Go through the Cytochrome C-Caspase Pathway
Q27005925Cell competition: how to eliminate your neighbours
Q90103107Drosophila Models of Cell Polarity and Cell Competition in Tumourigenesis
Q39155568Engulfing losers by winners in cancer: do cancer stem cells catch eat-me signals from noncancer stem cells?
Q36695589Mechanisms of cell competition: themes and variations
Q52310247Modelling Cooperative Tumorigenesis in Drosophila.

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