Phase II trial of fenretinide (NSC 374551) in patients with recurrent small cell lung cancer

scientific article published on 19 February 2009

Phase II trial of fenretinide (NSC 374551) in patients with recurrent small cell lung cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10637-009-9228-6
P698PubMed publication ID19225720

P50authorGregory P. KalemkerianQ124968136
Shirish M GadgeelQ124968314
Antoinette J WozniakQ124968320
Michael J KrautQ124968333
P2093author name stringFrancis P Worden
Ralph E Parchment
Rodney L Dunn
James Zwiebel
Bryan J Schneider
Collette M Hodges
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N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes.Q40734731
Mediation of N-(4-hydoxyphenyl)retinamide-induced apoptosis in human cancer cells by different mechanisms.Q40951916
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Growth inhibition and induction of apoptosis by fenretinide in small-cell lung cancer cell lines.Q50756405
A phase I-II preoperative biomarker trial of fenretinide in ascitic ovarian cancer.Q53594187
N-(4-hydroxyphenyl)retinamide: a Potent Inducer of Apoptosis in Human Neuroblastoma CellsQ58813531
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N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acidQ72657599
Twenty years of phase III trials for patients with extensive-stage small-cell lung cancer: perceptible progressQ73181495
Activity of fenretinide plus chemotherapeutic agents in small-cell lung cancer cell linesQ77922762
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Plasma retinol level reduction by the synthetic retinoid fenretinide: a one year follow-up study of breast cancer patientsQ93521069
P433issue6
P921main subjectphase II clinical trialQ42824440
P304page(s)571-578
P577publication date2009-02-19
P1433published inInvestigational New DrugsQ2312231
P1476titlePhase II trial of fenretinide (NSC 374551) in patients with recurrent small cell lung cancer
P478volume27