Beta-amyloid cortical deposits are accompanied by the loss of serotonergic neurons in the dog.

scientific article published in April 2009

Beta-amyloid cortical deposits are accompanied by the loss of serotonergic neurons in the dog. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/CNE.21985
P698PubMed publication ID19180552

P2093author name stringManuel Sarasa
Pedro Pesini
Germán Santamarina
Daniel Insua
María-Luisa Suárez
Vanessa Bernedo
P2860cites workMorphometry of the dorsal raphe nucleus serotonergic neurons in suicide victimsQ28142835
Distribution, morphology and number of monoamine-synthesizing and substance P-containing neurons in the human dorsal raphe nucleusQ28281755
Lack of localization of 5-HT6 receptors on cholinergic neurons: implication of multiple neurotransmitter systems in 5-HT6 receptor-mediated acetylcholine releaseQ28575664
Age-related changes in serotonin-immunoreactive neurons in the rat nucleus raphe dorsalis and nucleus centralis superior: a light microscope studyQ33214189
The noradrenergic system in Alzheimer and multi-infarct dementiasQ33755706
Alzheimer's disease: more than a 'cholinergic disorder' - evidence that cholinergic-monoaminergic interactions contribute to EEG slowing and dementiaQ34041861
Canine models for human genetic neurodegenerative diseasesQ34146955
The 5-HT6 Receptor Antagonist SB-271046 Reverses Scopolamine-Disrupted Consolidation of a Passive Avoidance Task and Ameliorates Spatial Task Deficits in Aged RatsQ34271590
Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminalsQ34276042
Spatial learning and memory as a function of age in the dog.Q34370735
Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves memory formation in an autoshaping learning taskQ34427413
Insights into Abeta and presenilin from a canine model of human brain agingQ34534201
Nucleus raphe dorsalis in Alzheimer's disease: neurofibrillary tangles and loss of large neuronsQ34695402
Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trialQ34798154
Nucleus raphe dorsalis in dementia of the Alzheimer type: neurofibrillary changes and neuronal packing density.Q48647860
Atlas of serotonergic cell bodies in the cat brainstem: an immunocytochemical analysisQ48650189
Distribution of beta-amyloid in the canine brainQ48768116
Cytoarchitecture of the human dorsal raphe nucleusQ48859752
The distribution of serotonin, met-enkephalin and beta-lipotropin-like immunoreactivity in neuronal perikarya of the cat brainstemQ48942874
A retrospective study of canine senile plaques and cerebral amyloid angiopathyQ49081533
Monoamine cell distribution in the cat brain stem. A fluorescence histochemical study with quantification of indolaminergic and locus coeruleus cell groupsQ49131247
Chronic alcoholics without Wernicke-Korsakoff syndrome or cirrhosis do not lose serotonergic neurons in the dorsal raphe nucleusQ49146736
Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging.Q51997691
Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog.Q52029125
Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer type and in Parkinson's disease with and without dementia and depression.Q53187673
The neuropathology of aminergic nuclei in Alzheimer's disease.Q53191668
Cell loss in the locus coeruleus in senile dementia of Alzheimer type.Q53199035
Vascular and parenchymal Abeta deposition in the aging dog: correlation with behavior.Q53238041
Quantitative analysis of the distribution of serotonin-immunoreactive cell bodies in the mouse brainQ67960360
A simple and sensitive antigen retrieval method for free-floating and slide-mounted tissue sectionsQ73351829
Canine cognitive deficit correlates with diffuse plaque maturation and S100beta (-) astrocytosis but not with insulin cerebrospinal fluid levelQ83827391
Effect of age and level of cognitive function on spontaneous and exploratory behaviors in the beagle dogQ35042013
The human raphe nuclei and the serotonergic system.Q35631866
Effects of age on measures of complex working memory span in the beagle dog (Canis familiaris) using two versions of a spatial list learning paradigmQ35974291
Further evidence for the cholinergic hypothesis of aging and dementia from the canine model of agingQ36082211
Region specific neuron loss in the aged canine hippocampus is reduced by enrichmentQ36380222
Topographical distribution of dorsal and median raphe neurons projecting to motor, sensorimotor, and visual cortical areas in the rat.Q36463013
Serotonin in Alzheimer-type dementia and other dementing illnesses.Q36609115
Structure and function of the brain serotonin systemQ36741599
Combining an antioxidant-fortified diet with behavioral enrichment leads to cognitive improvement and reduced brain pathology in aging canines: strategies for healthy agingQ36918473
Serotonin, memory, and the aging brainQ37712872
The canine as a model of human cognitive aging: recent developmentsQ38441952
New stereological methods for counting neuronsQ40843719
Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapyQ40960354
The canine as an animal model of human aging and dementiaQ41067453
The organization of serotonergic projections to cerebral cortex in primates: Retrograde transport studiesQ41140715
Dual serotoninergic projections to forebrain in the rat: Morphologically distinct 5-HT axon terminals exhibit differential vulnerability to neurotoxic amphetamine derivativesQ41150965
Region-specific age at onset of beta-amyloid in dogsQ41733900
The differential involvement of subcortical nuclei in senile dementia of Alzheimer's typeQ41775105
Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's diseaseQ42280312
Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseasesQ42438205
Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.Q42489289
Effect of selective cholinergic denervation on the serotonergic system: implications for learning and memoryQ42503800
Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human agingQ43405668
Cytoarchitecture of serotonin-synthesizing neurons in the pontine tegmentum of the human brainQ43426784
Serotonergic nuclei of the raphe are not affected in human ageingQ43558606
Aging of the serotonergic system in the rat forebrain: an immunocytochemical and neurochemical studyQ43687856
Oxidative damage increases with age in a canine model of human brain agingQ44068708
Nucleus-specific alteration of raphe neurons in human neurodegenerative disordersQ44289376
The progression of beta-amyloid deposition in the frontal cortex of the aged canineQ44810115
Cell loss in the nucleus raphes dorsalis in Alzheimer's diseaseQ44877143
Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depressionQ44915202
Evidence for decreased transport of tryptophan hydroxylase in Alzheimer's diseaseQ45310068
Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canineQ46089691
Visual-discrimination learning ability and beta-amyloid accumulation in the dog.Q46235992
Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysisQ46532797
Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies.Q46890602
Cognitive disturbances in old dogs suffering from the canine counterpart of Alzheimer's diseaseQ46901421
Immunocytochemical study of the dorsal and median raphe nuclei in patients with Alzheimer's disease prospectively assessed for behavioural changesQ47588776
The role of free radicals in canine counterpart of senile dementia of the Alzheimer typeQ47820058
A collaborative study of the emergence and clinical features of the major depressive syndrome of Alzheimer's diseaseQ47938327
The serotoninergic innervation of cerebral cortex: different classes of axon terminals arise from dorsal and median raphe nucleiQ48261287
Presynaptic serotonergic dysfunction in patients with Alzheimer's diseaseQ48263628
Assessing the effects of deprenyl on longevity and antioxidant defenses in different animal modelsQ48294336
Vulnerability to aging in the rat serotonergic systemQ48333322
The raphe nuclei of the cat brain stem: a topographical atlas of their efferent projections as revealed by autoradiographyQ48364298
Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphologyQ48406116
Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's diseaseQ48599203
Brain stem serotonin-synthesizing neurons in Alzheimer's disease: a clinicopathological correlationQ48606957
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)417-429
P577publication date2009-04-01
P1433published inThe Journal of Comparative NeurologyQ3186907
P1476titleBeta-amyloid cortical deposits are accompanied by the loss of serotonergic neurons in the dog.
P478volume513