Major histocompatibility complex class II-dependent unfolding, transport, and degradation of endogenous proteins

scientific article

Major histocompatibility complex class II-dependent unfolding, transport, and degradation of endogenous proteins is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.272.46.29127
P698PubMed publication ID9360989
P5875ResearchGate publication ID13868840

P2093author name stringVestberg M
Teyton L
Jackson MR
Lechler RI
Karlsson L
Peterson PA
Vaughan JH
Aichinger G
P2860cites workThe structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3Q24303524
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptideQ27731272
Expression of wild-type and mutant forms of influenza hemagglutinin: the role of folding in intracellular transportQ27865283
ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathwayQ27932376
Mice lacking the MHC class II-associated invariant chainQ28507606
Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expressionQ28585705
Protein folding in the cellQ29547792
Presentation of newly synthesized glycoproteins to CD4+ T lymphocytes. An analysis using influenza hemagglutinin transport mutantsQ30466290
Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigensQ34273916
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.Q34350288
In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DMQ36158655
Assembly of influenza hemagglutinin trimers and its role in intracellular transportQ36215440
Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutininQ36217109
Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assemblyQ36220205
Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatusQ36234402
Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP.Q36236461
Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cellsQ36275163
Chloroquine affects biosynthesis of Ia molecules by inhibiting dissociation of invariant (gamma) chains from alpha-beta dimers in B cellsQ36350981
Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chainQ36353030
Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chainQ36353070
Specificity and promiscuity among naturally processed peptides bound to HLA-DR allelesQ36361966
Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune diseaseQ36362580
Enhanced antigen presentation in the absence of the invariant chain endosomal localization signalQ36362597
Folding of influenza hemagglutinin in the endoplasmic reticulumQ36530148
Empty and peptide-containing conformers of class I major histocompatibility complex molecules expressed in Drosophila melanogaster cellsQ37351477
Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozymeQ37482282
Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virusQ37545426
Structural basis of immune recognition of influenza virus hemagglutininQ37925554
Protein degradation in the endoplasmic reticulumQ37947738
Quality control in the secretory pathwayQ40380586
Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cellsQ40537087
Invariant chain structure and MHC class II functionQ40968427
Human self-reactive T cell clones expressing identical T cell receptor beta chains differ in their ability to recognize a cryptic self-epitopeQ41234208
Antigen presentation mediated by recycling of surface HLA-DR molecules.Q41335304
The invariant chain inhibits presentation of endogenous antigens by a human fibroblast cell lineQ41456815
The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptideQ41640226
Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chainQ41660992
Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytesQ41661580
MHC class II-restricted presentation of intracellular antigenQ41694984
The minimal number of class II MHC-antigen complexes needed for T cell activationQ41724410
Invariant chain association with HLA-DR molecules inhibits immunogenic peptide bindingQ41731115
A single amino acid change in the cytoplasmic domain allows the influenza virus hemagglutinin to be endocytosed through coated pitsQ45839792
Intracellular transport of class II MHC molecules directed by invariant chain.Q45941447
Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulumQ46051539
Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathwaysQ46424023
Transient aggregation of major histocompatibility complex class II chains during assembly in normal spleen cells.Q49164800
A role for peptide in determining MHC class II structureQ59077345
Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied moleculesQ59096640
Differential expression and serologically distinct subpopulations of human Ia antigens detected with monoclonal antibodies to Ia alpha and beta chainsQ59662175
Immunodominance with progenitor B cell diversity in the neutralizing antibody repertoire to influenza infectionQ60344714
Immunochemically purified DR antigens in liposomes stimulate xenogeneic cytolytic T cells in secondary in vitro culturesQ68812264
Construction of influenza haemagglutinin genes that code for intracellular and secreted forms of the proteinQ70522566
Allelic differences affecting invariant chain dependency of MHC class II subunit assemblyQ72112282
Poor loading of major histocompatibility complex class II molecules with endogenously synthesized short peptides in the absence of invariant chainQ72508379
P433issue46
P407language of work or nameEnglishQ1860
P304page(s)29127-29136
P577publication date1997-11-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleMajor histocompatibility complex class II-dependent unfolding, transport, and degradation of endogenous proteins
P478volume272

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cites work (P2860)
Q42015843A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing
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Q36228485Virus-specific CD4+ T cells: ready for direct attack

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