A new approach to the design of sigma-2-selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamine-related polyamines at sigma-1 and sigma-2 receptor subtypes

scientific article

A new approach to the design of sigma-2-selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamine-related polyamines at sigma-1 and sigma-2 receptor subtypes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/JM00028A016
P698PubMed publication ID8295220

P2093author name stringDominguez C
Bowen WD
Williams W
de Costa BR
He XS
Cutts J
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)314-321
P577publication date1994-01-01
P1433published inJournal of Medicinal ChemistryQ900316
P1476titleA new approach to the design of sigma-2-selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamine-related polyamines at sigma-1 and sigma-2 receptor subtypes
P478volume37

Reverse relations

cites work (P2860)
Q288293444-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studies
Q46698599CB-64D and CB-184: ligands with high σ2 receptor affinity and subtype selectivity
Q37161130New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.
Q34138150Re-evaluation of phencyclidine low-affinity or "non-NMDA" binding sites
Q37777989Sigma receptors and their ligands in cancer biology: overview and new perspectives for cancer therapy
Q40913236Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor

Search more.