Lipoprotein(a) Associated Molecules are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis

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Lipoprotein(a) Associated Molecules are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis is …
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P356DOI10.1016/J.JACBTS.2017.02.004
P932PMC publication ID5685511
P698PubMed publication ID29147686

P50authorCalvin YeangQ56998685
Joseph L WitztumQ62567829
Sotirios TsimikasQ80167861
Amir RavandiQ87691607
Michael TorzewskiQ96192526
P2093author name stringXiaohong Yang
Laura Twardowski
Ulrich F W Franke
Jens Schmid
Andrea Edel
Rahul Bhindi
Stefan Kath
P2860cites workElevated lipoprotein(a) and risk of aortic valve stenosis in the general population.Q54694067
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Specific accumulation of lipoprotein(a) in balloon-injured rabbit aorta in vivoQ71089370
Bone formation and inflammation in cardiac valvesQ73635711
Oxidized low-density lipoprotein, angiotensin II and increased waist cirumference are associated with valve inflammation in prehypertensive patients with aortic stenosisQ84067868
Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic ValveQ85675771
Oxidation-specific epitopes and immunological responses: Translational biotheranostic implications for atherosclerosisQ26822962
Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease.Q34353340
A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasmaQ34656639
Effect of alirocumab, a monoclonal proprotein convertase subtilisin/kexin 9 antibody, on lipoprotein(a) concentrations (a pooled analysis of 150 mg every two weeks dosing from phase 2 trials).Q35212866
Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.Q35836894
Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humansQ36617508
Enzymatically Modified Low-Density Lipoprotein Is Present in All Stages of Aortic Valve Sclerosis: Implications for Pathogenesis of the DiseaseQ36836028
Genetic associations with valvular calcification and aortic stenosisQ37154922
Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a).Q37163064
Lipoprotein(a) vascular accumulation in mice. In vivo analysis of the role of lysine binding sites using recombinant adenovirusQ37372596
Lipid lowering on progression of mild to moderate aortic stenosis: meta-analysis of the randomized placebo-controlled clinical trials on 2344 patientsQ37899611
Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 studyQ38297438
Experimental Animal Models Evaluating the Causal Role of Lipoprotein(a) in Atherosclerosis and Aortic StenosisQ38701405
Lipoprotein(a) and oxidized phospholipids in calcific aortic valve stenosisQ38839978
Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a).Q38840197
3-Year Outcomes in High-Risk Patients Who Underwent Surgical or Transcatheter Aortic Valve ReplacementQ39859303
Calcification of the aortic valve: its progression and gradingQ40643514
Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve StenosisQ41372923
LPA induces osteoblast differentiation through interplay of two receptors: LPA1 and LPA4.Q43195931
Effect of Lipid lowering with rosuvastatin on progression of aortic stenosis: results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trialQ43202673
Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosisQ43638006
Oxidative stress modulates osteoblastic differentiation of vascular and bone cellsQ43702897
Elevated expression of lipoprotein-associated phospholipase A2 in calcific aortic valve disease: implications for valve mineralizationQ44621087
Reduction in lipoprotein(a) with PCSK9 monoclonal antibody evolocumab (AMG 145): a pooled analysis of more than 1,300 patients in 4 phase II trials.Q45904176
Autotaxin interacts with lipoprotein(a) and oxidized phospholipids in predicting the risk of calcific aortic valve stenosis in patients with coronary artery disease.Q45944920
Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients.Q45946808
Prognosis and risk factors in patients with asymptomatic aortic stenosis and their modulation by atorvastatin (20 mg).Q46387230
A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosisQ46535596
Impact of high-dose atorvastatin therapy and clinical risk factors on incident aortic valve stenosis in patients with cardiovascular disease (from TNT, IDEAL, and SPARCL).Q46625599
Valvular (18)F-Fluoride and (18)F-Fluorodeoxyglucose Uptake Predict Disease Progression and Clinical Outcome in Patients With Aortic Stenosis.Q52991181
P433issue3
P921main subjectLPAQ18028636
P304page(s)229-240
P577publication date2017-06-26
P1433published inJACC. Basic to Translational ScienceQ27727237
P1476titleLipoprotein(a) Associated Molecules are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis
P478volume2