A historical and evolutionary perspective on the biological significance of circulating DNA and extracellular vesicles

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A historical and evolutionary perspective on the biological significance of circulating DNA and extracellular vesicles is …
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scholarly articleQ13442814
editorialQ871232
review articleQ7318358

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P356DOI10.1007/S00018-016-2370-3
P698PubMed publication ID27652382

P50authorJanine AucampQ88357583
P2093author name stringAbel J Bronkhorst
Piet J Pretorius
Christoffel P S Badenhorst
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STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES: INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE IIIQ22066172
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Intercellular Transfer of Cancer Drug Resistance Traits by Extracellular VesiclesQ38598070
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Cell-free nucleic acids circulating in the plasma of colorectal cancer patients induce the oncogenic transformation of susceptible cultured cellsQ42830431
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Exercise is a potent stimulus for enhancing circulating DNase activity.Q53075964
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Unequal representation of different unique genomic DNA sequences in the cell-free plasma DNA of individual donors.Q54502856
Metabolic DNA as the origin of spontaneously released DNA?Q54797396
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Human genome completed (again)Q56068669
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Metabolic DNA in Heart and Skeletal Muscle and in the Intestine of MiceQ59096096
In vitro synthesis of DNA spontaneously released by bacteria or frog auriclesQ67240613
Microdensitometric and autoradiographic comparison of the DNA contents of foetal and adult rat liver nucleiQ67318142
Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granulesQ29614240
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteinsQ29615034
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Origins, structures, and functions of circulating DNA in oncologyQ30249103
Parental olfactory experience influences behavior and neural structure in subsequent generationsQ30435813
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Friedrich Miescher and the discovery of DNA.Q33984688
A new perspective on Darwin's PangenesisQ34011253
High fragmentation characterizes tumour-derived circulating DNA.Q34016528
Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancerQ34039531
Spontaneous release of DNA by human blood lymphocytes as shown in an in vitro systemQ34086089
How did East German genetics avoid Lysenkoism?Q34131369
Isolation and characterization of DNA from the plasma of cancer patientsQ34186554
Prostasomal DNA characterization and transfer into human spermQ34189593
The Occurrence of Single-Stranded DNA in the Serum of Patients with Systemic Lupus Erythematosus and Other DiseasesQ34215374
Nucleic acids spontaneously released by living frog auriclesQ34215507
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosusQ34224780
Radiation-induced bystander effects: past history and future directionsQ34250876
Non-invasive prenatal measurement of the fetal genomeQ34286073
Profiling of microRNAs in exosomes released from PC-3 prostate cancer cellsQ34299962
Interaction between prostasomes and spermatozoa from human semenQ34320254
An Mg2+ and Ca2+-Stimulated Adenosine Triphosphatase in Human Prostatic Fluid - Part II*Q34348903
Microparticles as regulators of inflammation: novel players of cellular crosstalk in the rheumatic diseasesQ34463608
Are we Genomic Mosaics? Variations of the Genome of Somatic Cells can Contribute to Diversify our PhenotypesQ34479587
Cancer progression mediated by horizontal gene transfer in an in vivo model.Q34534548
The prostasome: its secretion and function in man.Q34564564
Robustness and evolvability in genetic regulatory networksQ34594618
Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA.Q34632614
Circulating microparticles: square the circleQ34680832
Complete genes may pass from food to human blood.Q34921290
Human prostasomes contain chromosomal DNA.Q34921396
Circulating DNA: a new diagnostic gold mine?Q34999413
Global organellar proteomicsQ35062593
ARF6-regulated shedding of tumor cell-derived plasma membrane microvesiclesQ35148002
Presence of RNA in the nucleoprotein complex spontaneously released by human lymphocytes and frog auricles in cultureQ67376390
Informational DNA synthesis distinguished from that of nuclear DNA by inhibitors of DNA synthesisQ68481470
DNA digestion and chromatin condensation during nuclear death in TetrahymenaQ71139338
Formation and Loss of DNA in Intestinal EpitheliumQ71242228
Metabolic DNA and the problem of ageingQ71659999
Radiation-induced clastogenic factors: anticlastogenic effect of Ginkgo biloba extractQ71941094
Synthesis of a metabolically labile DNA in the maturing root cells of Vicia fabaQ72898694
Tumor DNA circulating in the plasma might play a role in metastasis. The hypothesis of the genometastasisQ73043024
Horizontal transfer of DNA and the "genometastasis hypothesis"Q73413349
In vitro stimulation by tumour cell media of [3H]-thymidine incorporation by mouse spleen lymphocytesQ73577641
AUTORADIOGRAPHIC STUDIES OF THE FATE OF HETEROLOGOUS DNA AFTER INJECTION INTO MICEQ76642124
Nuclear uptake of labelled adenine in the seminal vesicle of the mouseQ77065857
Metabolic activity of DNA as shown by autoradiographsQ78519691
Appearance of genetic transforming activity in pneumococcal culturesQ78957427
Experiments on Pekin ducks treated with DNA from Khaki Campbell ducksQ79152894
[Interspecific transformation of Neisseria by culture slime containing deoxyribonucleate]Q79310927
Circulating DNA: intracellular and intraorgan messenger?Q79362835
Increased concentrations of cell-free plasma DNA after exhaustive exerciseQ80496332
DNA Synthesis in Aluminum-Treated Roots of BarleyQ80895058
Role of extracellular DNA oxidative modification in radiation induced bystander effects in human endotheliocytesQ82038205
Circulating nucleic acids in plasma and serum. Recent developmentsQ82218491
Extracellular DNA fragmentsQ82218520
Effect of cell-free DNA of patients with cardiomyopathy and rDNA on the frequency of contraction of electrically paced neonatal rat ventricular myocytes in cultureQ82218737
Clinical use of circulating nucleosomesQ83081813
Oxidative stress as a significant factor for development of an adaptive response in irradiated and nonirradiated human lymphocytes after inducing the bystander effect by low-dose X-radiationQ84091395
Darwin's Pangenesis and molecular medicineQ84713427
Spontaneous release of DNA in sequential genetic order by Bacillus subtilisQ93791855
Exosomes: secreted vesicles and intercellular communicationsQ35161550
Messenger DNA in higher plantsQ35196677
Circulating nucleic acids in plasma and serum (CNAPS) and its relation to stem cells and cancer metastasis: state of the issueQ35692795
Roll over Weismann: extracellular vesicles in the transgenerational transmission of environmental effectsQ35857342
Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generationsQ36150116
Ultrastructure and cytochemistry of metabolic DNA in TipulaQ36188023
Stability of DNA in Purkinje cell nuclei of the mouse. An autoradiographic studyQ36202458
Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viabilityQ36340010
Multigenerational epigenetic adaptation of the hepatic wound-healing responseQ36374096
Formation and fate of platelet microparticlesQ36391350
METABOLICALLY LABILE DEOXYRIBONUCLEIC ACIDQ36399852
Macronuclear duplication in the ciliated protozoan Euplotes.Q36424743
Is there "metabolic" DNA in the mouse seminal vesicle?Q36425373
A STUDY OF THE PENETRATION OF MAMMALIAN CELLS BY DEOXYRIBONUCLEIC ACIDS.Q36425630
Historical and modern genetics of plant graft hybridizationQ36492696
Receptors in spermatozoa: are they real?Q36496605
Circulating nucleic acids (CNAs) and cancer--a surveyQ36669780
Oxidized extracellular DNA as a stress signal in human cellsQ36711791
Transcription of Spontaneously Released Bacterial Deoxyribonucleic Acid in Frog AuriclesQ36839964
Characterizing blood microparticles: technical aspects and challenges.Q37004064
Circulating nucleic acids in plasma and serum (CNAPS): applications in oncologyQ37014663
Transformation of Neisseria meningitidis by deoxyribonucleates from cells and from culture slime.Q37454270
Gene amplification: an example of accelerated evolution in tumorigenic cellsQ37552193
The conversion of spring wheat into winter wheat and vice versa: false claim or Lamarckian inheritance?Q37778215
The virtosome-a novel cytosolic informative entity and intercellular messengerQ37799777
Microparticles: protagonists of a novel communication network for intercellular information exchangeQ37804649
Origin, translocation and destination of extracellular occurring DNA--a new paradigm in genetic behaviourQ37833275
Continuous adaptation through genetic communication - a putative role for cell-free DNA.Q38007536
Circulating cell-free DNA: an up-coming molecular marker in exercise physiology.Q38018379
Reprogramming and the mammalian germline: the Weismann barrier revisitedQ38040551
Transgenerational epigenetic inheritance: focus on soma to germline information transfer.Q38069010
How life changes itself: the Read-Write (RW) genomeQ38123302
Oxidized extracellular DNA as a stress signal that may modify response to anticancer therapy.Q38138674
An extracellular DNA mediated bystander effect produced from low dose irradiated endothelial cells.Q38336791
P433issue23
P921main subjectextracellular vesicleQ21097485
P304page(s)4355-4381
P577publication date2016-09-20
P1433published inCellular and Molecular Life SciencesQ5058352
P1476titleA historical and evolutionary perspective on the biological significance of circulating DNA and extracellular vesicles
P478volume73

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cites work (P2860)
Q100634927Cell-free DNA in plasma as an essential immune system regulator
Q88956843Extracellular DNA in natural environments: features, relevance and applications
Q40134679Extracellular Vesicle Biology in the Pathogenesis of Lung Disease
Q64254000Increased Transfection of the Easily Oxidizable GC-Rich DNA Fragments into the MCF7 Breast Cancer Cell
Q38711643Kinetic analysis, size profiling, and bioenergetic association of DNA released by selected cell lines in vitro
Q59329510New insights into structural features and optimal detection of circulating tumor DNA determined by single-strand DNA analysis
Q64121578Quantifying circulating cell-free DNA in humans
Q90724935Translational Application of Circulating DNA in Oncology: Review of the Last Decades Achievements

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