Glaucoma as a neuropathy amenable to neuroprotection and immune manipulation

scientific article

Glaucoma as a neuropathy amenable to neuroprotection and immune manipulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0079-6123(08)01126-6
P698PubMed publication ID18929122

P50authorMichal SchwartzQ21264411
P2093author name stringAnat London
P2860cites workModulating the immune system: a vaccine for glaucoma?Q22305673
Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous systemQ24539880
Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune diseaseQ24671661
Oxidative stress in neurodegeneration: cause or consequence?Q28275946
Caspases: enemies withinQ29547315
Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trialQ30881058
The relationship between intraocular pressure and visual field progression in glaucomaQ30997514
Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma TrialQ31113402
Proteomic identification of nitrated proteins in Alzheimer's disease brainQ31144652
Antigenic specificity of immunoprotective therapeutic vaccination for glaucomaQ33187884
Proteomic identification of oxidatively modified retinal proteins in a chronic pressure-induced rat model of glaucomaQ33222315
Protective autoimmunity is a physiological response to CNS trauma.Q33947118
Cellular response to oxidative stress: signaling for suicide and survivalQ34138566
Beyond intraocular pressure: neuroprotective strategies for future glaucoma therapyQ34194014
Excitatory amino acids as a final common pathway for neurologic disorders.Q34321926
Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective.Q34418439
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomyQ34486849
Targeting protein aggregation in neurodegeneration--lessons from polyglutamine disordersQ34548624
Glutamate neurotoxicity and diseases of the nervous systemQ34560997
Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylationQ34628531
Is there more to glaucoma treatment than lowering IOP?Q34712829
Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: implications for glaucomaQ34734517
Glial modulation of retinal ganglion cell death in glaucomaQ35059644
Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cellsQ35063857
T cell immunity to copolymer 1 confers neuroprotection on the damaged optic nerve: possible therapy for optic neuropathiesQ35160575
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's diseaseQ35320917
Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequencesQ35677091
Surgical lowering of elevated intraocular pressure in monkeys prevents progression of glaucomatous diseaseQ35777463
The optic nerve head as a biomechanical structure: a new paradigm for understanding the role of IOP-related stress and strain in the pathophysiology of glaucomatous optic nerve head damageQ35957595
Lessons for glaucoma from other neurodegenerative diseases: can one treatment suit them all?Q36180444
Protective effects of melatonin in experimental free radical-related ocular diseases.Q36379509
The role of oxidative stress in the dysregulation of gene expression and protein metabolism in neurodegenerative diseaseQ36399776
Inhibition of nitric-oxide synthase 2 by aminoguanidine provides neuroprotection of retinal ganglion cells in a rat model of chronic glaucomaQ36440373
The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis.Q36522329
A century-old debate on protein aggregation and neurodegeneration enters the clinicQ36628151
From benefit to damage. Glutamate and advanced glycation end products in Alzheimer brainQ36629895
Glaucoma as a neurodegenerative diseaseQ36736043
Pharmacological neuroprotection for glaucomaQ36770323
Glutamate in the mammalian CNS.Q37610496
Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damageQ38201300
Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators.Q38330556
Neuronal death in glaucomaQ40827206
Molecular basis of glutamate toxicity in retinal ganglion cells.Q40873212
The effects of ifenprodil and eliprodil on voltage-dependent Ca2+ channels and in gerbil global cerebral ischaemiaQ41213517
Outcomes of trabeculectomy for primary open-angle glaucomaQ41428616
Caspases: key mediators of apoptosisQ41760384
Biostatistical evidence for two distinct chronic open angle glaucoma populationsQ42620508
Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve headQ42635765
Vaccination for neuroprotection in the mouse optic nerve: implications for optic neuropathies.Q43517448
The tissue-specific self-pathogen is the protective self-antigen: the case of uveitis.Q44209323
Dopamine, through the extracellular signal-regulated kinase pathway, downregulates CD4+CD25+ regulatory T-cell activity: implications for neurodegeneration.Q44969003
Vaccination with autoantigen protects against aggregated beta-amyloid and glutamate toxicity by controlling microglia: effect of CD4+CD25+ T cellsQ45154170
Effect of glatiramer acetate on primary and secondary degeneration of retinal ganglion cells in the rat.Q45280864
T-cell-based vaccination for morphological and functional neuroprotection in a rat model of chronically elevated intraocular pressure.Q46647187
Factors influencing optic nerve head biomechanicsQ46774812
Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approachQ46868947
The use of cyclodialysis to limit exposure to elevated intraocular pressure in rat glaucoma modelsQ46986013
Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophinsQ48215686
Glutamate toxicity in chronic neurodegenerative disease.Q48291440
Neurodegeneration and neuroprotection in glaucoma: development of a therapeutic neuroprotective vaccine: the Friedenwald lectureQ48357321
The role of specific ions in glutamate neurotoxicityQ48364787
Delayed functional loss in glaucoma. LII Edward Jackson Memorial LectureQ48387731
Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells In vivo.Q48539147
Reduced glutamate uptake by retinal glial cells under ischemic/hypoxic conditions.Q52533903
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.Q53872479
Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes.Q53913933
ALS, SOD and peroxynitriteQ59070047
Excitotoxicity and nitric oxide in Parkinson's disease pathogenesisQ64869641
N-methyl-D-aspartate-induced neurotoxicity in the adult rat retinaQ68126319
Protective effects of flunarizine on ischemic injury in the rat retinaQ68140166
The benefit of early trabeculectomy versus conventional management in primary open angle glaucoma relative to severity of diseaseQ69572781
Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosisQ70958165
In vivo protection against NMDA-induced neurodegeneration by MK-801 and nimodipine: combined therapy and temporal course of protectionQ71562869
Glutaate-induced retinal degeneration in neonatal mice. Electron microscopy of the acutely evolving lesionQ72397927
Checkpoints of dueling dimers foil death wishesQ72790765
Production of neurotrophins by activated T cells: implications for neuroprotective autoimmunityQ73098016
Morphological aspects of spinal cord autoimmune neuroprotection: colocalization of T cells with B7--2 (CD86) and prevention of cyst formationQ73727740
Potential role for Ginkgo biloba extract in the treatment of glaucomaQ73735546
Autoreactive T cells induce neurotrophin production by immune and neural cells in injured rat optic nerve: implications for protective autoimmunityQ74558134
Trafficking of molecules and metabolic signals in the retinaQ77057696
Primary open-angle glaucomaQ80122027
P407language of work or nameEnglishQ1860
P304page(s)375-384
P577publication date2008-01-01
P1433published inProgress in Brain ResearchQ15800382
P1476titleGlaucoma as a neuropathy amenable to neuroprotection and immune manipulation
P478volume173

Reverse relations

cites work (P2860)
Q42647905Association of lens vault with narrow angles among different ethnic groups
Q37552148Associations of sleep duration with open angle glaucoma in the Korea national health and nutrition examination survey
Q41489091Biomarkers of primary open-angle glaucoma
Q38077553The immunological basis of degenerative diseases of the eye.
Q37809108The role of melatonin in glaucoma: implications concerning pathophysiological relevance and therapeutic potential

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