Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast

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Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast is …
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scholarly articleQ13442814

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P356DOI10.1038/NG1359
P698PubMed publication ID15133512
P5875ResearchGate publication ID8571386

P50authorVincent PennaneachQ57159999
P2093author name stringRichard D Kolodner
P2860cites workA telomerase component is defective in the human disease dyskeratosis congenitaQ22010917
Deletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndromeQ24532112
Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeresQ24536297
Specific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repairQ27935229
Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination eventsQ27936385
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenitaQ28189076
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2Q28509254
An alternative pathway for yeast telomere maintenance rescues est1- senescenceQ29616135
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repairQ29618204
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in miceQ33914498
DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpointsQ33963987
Mechanisms of chromosome-end protectionQ34688443
Maintenance of genome stability in Saccharomyces cerevisiaeQ34762852
The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line.Q34786093
Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisaeQ35978538
Telomere length dynamics and chromosomal instability in cells derived from telomerase null miceQ36255827
Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiaeQ39449233
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutantsQ39860143
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutantsQ41688249
Telomere dysfunction increases mutation rate and genomic instabilityQ43709760
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.Q44079733
NEJ1 prevents NHEJ-dependent telomere fusions in yeast without telomeraseQ44455874
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiaeQ46062549
Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiaeQ46200700
Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joiningQ46531438
Telomere states and cell fatesQ46830116
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell linesQ73851376
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)612-617
P577publication date2004-05-09
P1433published inNature GeneticsQ976454
P1476titleRecombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast
P478volume36