Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells.

scientific article published on 8 October 2008

Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10637-008-9183-7
P698PubMed publication ID18841326
P5875ResearchGate publication ID23305721

P50authorThomas SzekeresQ15850813
Georg KrupitzaQ30002284
Walter JägerQ39066021
Michael GruschQ39813444
Andreas LacknerQ59561725
Sibylle MadlenerQ61779768
P2093author name stringPhilipp Saiko
Thomas Erker
Monika Fritzer-Szekeres
Zsuzsanna Horvath
Astrid Bernhaus
Maria Ozsvar-Kozma
Norbert Handler
Margit Jaschke
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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitorsQ29547463
N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine.Q33301354
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A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed fibroblastsQ34554484
Present and future treatment of pancreatic cancerQ34718249
The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1.Q36644183
Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene.Q36694528
Induction of apoptosis in proliferating human endothelial cells by the tumor-specific antiangiogenesis agent combretastatin A-4.Q36899101
Diet and pancreatic cancer: a case-control studyQ38592134
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Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cellsQ41021779
In vitro evaluation of the antineoplastic activity of combretastatin A-4, a natural product from Combretum caffrum (arid shrub).Q41574653
Differential cytotoxicity of combretastatins A1 and A4 in two daunorubicin-resistant P388 cell linesQ41749677
Ribonucleotide reductase and cell proliferation. I. Variations of ribonucleotide reductase activity with tumor growth rate in a series of rat hepatomas.Q43608910
Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells.Q43640339
DNA polymerase and topoisomerase II inhibitors from Psoralea corylifoliaQ43746938
Resveratrol inhibits proliferation and induces apoptosis in human pancreatic cancer cellsQ44200538
Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerizationQ44569587
Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationshipQ45090641
Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) on adenoma development in the Apc(Min+) mouse and cyclooxygenase-2 in human-derived colon cancer cellsQ45249210
Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure-activity relationship.Q45302719
Early onset pancreatic cancer: evidence of a major role for smoking and genetic factors.Q51737724
Antioxidant activity of resveratrol, piceatannol and 3,3',4,4',5,5'-hexahydroxy-trans-stilbene in three leukemia cell lines.Q53343691
Role of ribonucleotide reductase in expression in the neoplastic program.Q53571837
Polyphenols: Chemistry, Dietary Sources, Metabolism, and Nutritional SignificanceQ56610830
Biochemical and antitumor activity of trimidox, a new inhibitor of ribonucleotide reductaseQ57909898
Wine Antioxidant Polyphenols Inhibit the Proliferation of Human Prostate Cancer Cell LinesQ58239713
Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cellsQ74163308
Resveratrol, a remarkable inhibitor of ribonucleotide reductaseQ74191674
Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphateQ77394912
Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cellsQ77402133
Reactivity studies of the tyrosyl radical in ribonucleotide reductase from Mycobacterium tuberculosis and Arabidopsis thaliana--comparison with Escherichia coli and mouseQ77750948
P433issue5
P921main subjectpancreatic carcinomaQ18556536
P304page(s)393-401
P577publication date2008-10-08
P1433published inInvestigational New DrugsQ2312231
P1476titleAntitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells
P478volume27

Reverse relations

cites work (P2860)
Q39638532Antiproliferative effect of resveratrol in pancreatic cancer cells
Q34695119Chemosensitization of tumors by resveratrol
Q39110541Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells.
Q47614745Elastographic Assessment of Xenograft Pancreatic Tumors
Q28552026Novel Promising Estrogenic Receptor Modulators: Cytotoxic and Estrogenic Activity of Benzanilides and Dithiobenzanilides
Q36763100Pancreatic cancer chemoprevention by phytochemicals
Q38568979Resveratrol in the treatment of pancreatic cancer.
Q41841905Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer
Q38873022Rotenone affects p53 transcriptional activity and apoptosis via targeting SIRT1 and H3K9 acetylation in SH-SY5Y cells
Q39770059Selective proapoptotic activity of polyphenols from red wine on teratocarcinoma cell, a model of cancer stem-like cell

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