CEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells

scientific article published on 5 October 2008

CEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.1661
P698PubMed publication ID18836450
P5875ResearchGate publication ID23300953

P50authorKristian RiesbeckQ58148701
P2093author name stringNorbert Suttorp
Wolfgang Zimmermann
Hortense Slevogt
Bernhard B Singer
Bastian Opitz
Julia Eitel
Lothar Lucka
Janine Zweigner
Andreas Hocke
Solveig Zabel
Bettina Temmesfeld-Wollbrueck
Philippe D N'guessan
P2860cites workSHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activityQ72993747
The immunoglobulin D-binding part of the outer membrane protein MID from Moraxella catarrhalis comprises 238 amino acids and a tetrameric structureQ74444907
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TLRs play good cop, bad cop in the lungQ81442371
Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathwayQ24300160
Reduced interleukin-8 production by cystic fibrosis airway epithelial cellsQ26341680
Pathogen recognition and innate immunityQ27861084
CEACAM1: contact-dependent control of immunityQ28242244
You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signallingQ28246907
SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoformsQ28511516
Up on the tightrope: natural killer cell activation and inhibitionQ29619175
A novel cell-binding mechanism of Moraxella catarrhalis ubiquitous surface protein UspA: specific targeting of the N-domain of carcinoembryonic antigen-related cell adhesion molecules by UspA1.Q31136213
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Immune inhibitory receptorsQ34054933
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The role of bacteria in airway inflammation in exacerbations of chronic obstructive pulmonary diseaseQ36462964
New players in TLR-mediated innate immunity: PI3K and small Rho GTPases.Q36487072
Enhancing and confirming the specificity of RNAi experimentsQ36575386
Lessons from meningococcal carriage studiesQ36711465
Airway inflammation and bronchial bacterial colonization in chronic obstructive pulmonary diseaseQ37144323
Colony-stimulating factors in inflammation and autoimmunity.Q37190439
Moraxella catarrhalis induces ERK- and NF-kappaB-dependent COX-2 and prostaglandin E2 in lung epithelium.Q40126155
Binding of Escherichia coli and Salmonella strains to members of the carcinoembryonic antigen family: differential binding inhibition by aromatic alpha-glycosides of mannoseQ40150811
Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger-like mechanism and initiates a TLR2- and partly NOD1-dependent inflammatory immune responseQ40217556
Activation of Ca2+-dependent signaling by TLR2.Q40259568
Live Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis activate the inflammatory response through Toll-like receptors 2, 4, and 9 in species-specific patternsQ40274487
Moraxella catarrhalis induces inflammatory response of bronchial epithelial cells via MAPK and NF-kappaB activation and histone deacetylase activity reductionQ40332613
TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cellsQ40555493
Differential recognition of members of the carcinoembryonic antigen family by Afa/Dr adhesins of diffusely adhering Escherichia coli (Afa/Dr DAEC).Q40558577
Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signalingQ40739732
Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinaseQ40808012
Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathwayQ40819427
The N-domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeaeQ41148166
Moraxella catarrhalis in chronic obstructive pulmonary disease: burden of disease and immune responseQ41777860
Paired Ig-like receptors bind to bacteria and shape TLR-mediated cytokine productionQ42830079
Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytesQ43890850
Conformational analysis of opacity proteins from Neisseria meningitidisQ44188682
Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptorsQ44655587
CEACAM1 dynamics during neisseria gonorrhoeae suppression of CD4+ T lymphocyte activationQ46614202
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1.Q46661965
Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophilsQ47725465
Involvement of SHIP in TLR2-induced neutrophil activation and acute lung injury.Q53620526
The variable P5 proteins of typeable and non-typeable Haemophilus influenzae target human CEACAM1Q58870834
The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasisQ64377894
P433issue11
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)1270-1278
P577publication date2008-10-05
P1433published inNature ImmunologyQ1071725
P1476titleCEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells
P478volume9

Reverse relations

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