| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.NEUROBIOLAGING.2008.07.008 |
| P698 | PubMed publication ID | 18715677 |
| P2093 | author name string | Kostas Vekrellis | |
| Leonidas Stefanis | |||
| Evangelia Emmanouilidou | |||
| P433 | issue | 6 | |
| P921 | main subject | Synuclein | Q24767155 |
| P304 | page(s) | 953-968 | |
| P577 | publication date | 2008-08-20 | |
| P1433 | published in | Neurobiology of Aging | Q7002141 |
| P1476 | title | Cell-produced alpha-synuclein oligomers are targeted to, and impair, the 26S proteasome | |
| P478 | volume | 31 |
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| Q37874930 | A deadly spread: cellular mechanisms of α-synuclein transfer |
| Q34030874 | A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo. |
| Q33444800 | Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy |
| Q36148314 | Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders |
| Q27021628 | Ageing and Parkinson's disease: why is advancing age the biggest risk factor? |
| Q33466066 | Aging is not associated with proteasome impairment in UPS reporter mice |
| Q46321755 | Alpha-synuclein oligomers: a new hope. |
| Q36336723 | Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease. |
| Q38039084 | An extracellular mechanism that can explain the neurotoxic effects of α-synuclein aggregates in the brain |
| Q47126958 | Autophagy enhancement is rendered ineffective in presence of α-synuclein in melanoma cells |
| Q34020622 | Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism. |
| Q37587793 | Biochemical and pathological correlates of cognitive and behavioural change in DLB/PDD. |
| Q61808028 | Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology |
| Q39097048 | Cell Biology and Pathophysiology of α-Synuclein |
| Q37376117 | Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps |
| Q37347595 | Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival |
| Q64949212 | Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease. |
| Q47119009 | Conformational Ensembles of α-Synuclein Derived Peptide with Different Osmolytes from Temperature Replica Exchange Sampling |
| Q38704492 | DT-diaphorase Protects Against Autophagy Induced by Aminochrome-Dependent Alpha-Synuclein Oligomers. |
| Q61446034 | Dementia with Lewy bodies: an update and outlook |
| Q34407400 | Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2. |
| Q55003043 | Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology. |
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| Q37916635 | Drug targets from genetics: α-synuclein |
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| Q89720803 | Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein |
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| Q37461364 | Lysosomal impairment in Parkinson's disease |
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| Q47406006 | Mechanistic contributions of FBXO7 to Parkinson disease. |
| Q36640417 | Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein |
| Q37997568 | Misfolded PrP and a novel mechanism of proteasome inhibition |
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| Q28259424 | Modulating self-assembly of amyloidogenic proteins as a therapeutic approach for neurodegenerative diseases: strategies and mechanisms |
| Q37483616 | Modulation of alpha-synuclein aggregation by dopamine: a review. |
| Q33715640 | Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathies |
| Q35688796 | Molecular chaperones in Parkinson's disease--present and future |
| Q42394229 | Molecular tweezers for lysine and arginine - powerful inhibitors of pathologic protein aggregation |
| Q39489133 | N-terminal deletion does not affect α-synuclein membrane binding, self-association and toxicity in human neuroblastoma cells, unlike yeast |
| Q42269174 | Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo |
| Q28585769 | Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein |
| Q28115384 | Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation |
| Q36319286 | Parkinson disease |
| Q37947720 | Pathological roles of α-synuclein in neurological disorders |
| Q38303579 | Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like Propagation |
| Q27026029 | Protein degradation pathways in Parkinson's disease: curse or blessing |
| Q26750630 | Redox Imbalance and Viral Infections in Neurodegenerative Diseases |
| Q28273075 | Reducing synuclein accumulation improves neuronal survival after spinal cord injury |
| Q33708946 | Reduction of RPT6/S8 (a Proteasome Component) and Proteasome Activity in the Cortex is Associated with Cognitive Impairment in Lewy Body Dementia |
| Q24294333 | Replacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell death |
| Q28080551 | Seeking a mechanism for the toxicity of oligomeric α-synuclein |
| Q34519909 | Sequestration of cellular interacting partners by protein aggregates: implication in a loss-of-function pathology |
| Q38807183 | Silencing of SIAH1 in SH-SY5Y affects α-synuclein degradation pathway |
| Q38550428 | Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies |
| Q35675406 | Targeted Overexpression of α-Synuclein by rAAV2/1 Vectors Induces Progressive Nigrostriatal Degeneration and Increases Vulnerability to MPTP in Mouse |
| Q52615753 | Targeted disruption of neuronal 19S proteasome subunits induces the formation of ubiquitinated inclusions in the absence of cell death. |
| Q38000327 | Targeting intracellular and extracellular alpha-synuclein as a therapeutic strategy in Parkinson's disease and other synucleinopathies |
| Q90073258 | Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts |
| Q24299289 | The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity |
| Q38996038 | The Proteasome Inhibition Model of Parkinson's Disease |
| Q64102410 | The Roles of Post-translational Modifications on α-Synuclein in the Pathogenesis of Parkinson's Diseases |
| Q38279572 | The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans |
| Q33991720 | The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells. |
| Q21202835 | alpha-Synuclein and neuronal cell death |
| Q38039369 | α-Synuclein and neuronal cell death |
| Q38039881 | α-Synuclein and protein degradation systems: a reciprocal relationship |
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