Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells.

scientific article

Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.3761-04.2005
P932PMC publication ID6725155
P698PubMed publication ID15758165

P50authorReinhard JahnQ2140756
Erwin NeherQ77126
Volker HauckeQ18632468
Jakob B. SørensenQ30502127
P2093author name stringThorsten Lang
Michael Krauss
Ira Milosevic
Gábor Nagy
P2860cites workA role for a wortmannin-sensitive phosphatidylinositol-4-kinase in the endocytosis of muscarinic cholinergic receptorsQ24315812
New EMBO members' review: actin cytoskeleton regulation through modulation of PI(4,5)P(2) raftsQ24535616
ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type IgammaQ24675779
Examining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+Q26269939
Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin IQ26269979
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formationQ28139699
PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapseQ28198985
Mints, Munc18-interacting proteins in synaptic vesicle exocytosisQ28256295
Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca(2+)-activated secretionQ28257147
Specificity and mechanism of action of some commonly used protein kinase inhibitorsQ28344791
SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosisQ28364095
Specific binding of phosphatidylinositol 4,5-bisphosphate to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosisQ28565330
SNAREs in native plasma membranes are active and readily form core complexes with endogenous and exogenous SNAREsQ28571757
Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphateQ28616287
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)Q28640016
Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scaleQ30476234
Phosphoinositides in membrane traffic at the synapseQ32066953
PI(4,5)P(2) regulation of surface membrane trafficQ34309091
Emerging roles of presynaptic proteins in Ca++-triggered exocytosisQ34979915
Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cellsQ34982315
Inhibition of quantal release from motor nerve by wortmanninQ35041434
Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide poolsQ36255578
Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosisQ36293644
A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosisQ36323826
ARF6 regulates a plasma membrane pool of phosphatidylinositol(4,5)bisphosphate required for regulated exocytosisQ36325060
Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagminQ36693214
Dibasic amino acid residues at the carboxy-terminal end of kinase homology domain participate in the plasma membrane localization and function of phosphatidylinositol 5-kinase gammaQ40549044
GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanismQ40871328
A cell-free system for regulated exocytosis in PC12 cellsQ40903792
The role of PtdIns(4,5)P2 in exocytotic membrane fusionQ41693629
Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP.Q41882249
Dissection of three Ca2+-dependent steps leading to secretion in chromaffin cells from mouse adrenal slicesQ42498061
Dynamics of phosphatidylinositol 4,5-bisphosphate in actin-rich structuresQ42800160
Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.Q43999078
Effects of 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one on synaptic vesicle cycling at the frog neuromuscular junction.Q44251927
Synapsin I-associated phosphatidylinositol 3-kinase mediates synaptic vesicle delivery to the readily releasable poolQ44445845
Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25.Q44758007
An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene expression systemQ45747120
Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinasesQ49054230
PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane.Q55038004
ATP-dependent inositide phosphorylation required for Ca2+-activated secretionQ56689852
A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2as Being Important in ExocytosisQ56689853
Ca2+-Triggered Peptide Secretion in Single Cells Imaged with Green Fluorescent Protein and Evanescent-Wave MicroscopyQ58450914
MgATP-independent and MgATP-dependent exocytosis. Evidence that MgATP primes adrenal chromaffin cells to undergo exocytosisQ69736628
Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cellsQ74344711
The C2 domains of Rabphilin3A specifically bind phosphatidylinositol 4,5-bisphosphate containing vesicles in a Ca2+-dependent manner. In vitro characteristics and possible significanceQ74465513
Possible involvement of phosphatidylinositol 3-kinase in regulated exocytosis: studies in chromaffin cells with inhibitor LY294002Q74593393
Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivityQ77295927
Protein kinase C-dependent phosphorylation of synaptosome-associated protein of 25 kDa at Ser187 potentiates vesicle recruitmentQ78477861
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)2557-2565
P577publication date2005-03-01
P1433published inJournal of NeuroscienceQ1709864
P1476titlePlasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells
P478volume25

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