Induction of mitochondrial apoptotic pathway in triple negative breast carcinoma cells by methylglyoxal via generation of reactive oxygen species

scientific article

Induction of mitochondrial apoptotic pathway in triple negative breast carcinoma cells by methylglyoxal via generation of reactive oxygen species is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/MC.22665
P698PubMed publication ID28418078

P50authorManju RayQ21293248
P2093author name stringAnirban Roy
Arghya Adhikary
Manisha Ahir
Kuladip Jana
Saurav Bhattacharya
Pravat Kumar Parida
P2860cites workAdvanced glycation end-products induce injury to pancreatic beta cells through oxidative stressQ50515910
Advanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes.Q53582377
Molecular characterization of mitochondrial apoptosis-inducing factorQ22001452
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysQ25939005
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responsesQ27861101
ROS homeostasis and metabolism: a dangerous liason in cancer cellsQ28075971
Expression of glyoxalase I and II in normal and breast cancer tissuesQ28190025
Reactive oxygen species, cellular redox systems, and apoptosisQ28393669
Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells.Q30382534
A simple protocol for the subcellular fractionation of skeletal muscle cells and tissue.Q31096596
Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancerQ33220463
Labeling nuclear DNA with hoechst 33342.Q33785543
Role of reactive oxygen species (ROS) in apoptosis inductionQ34188867
Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypesQ34221728
Induction of apoptotic cell death by methylglyoxal and 3-deoxyglucosone in macrophage-derived cell linesQ34393482
Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cellsQ35934833
High Expression of Pyruvate Kinase M2 is Associated with Chemosensitivity to Epirubicin and 5-Fluorouracil in Breast CancerQ36190132
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell deathQ36365164
Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growthQ36569036
Roles of AKT signal in breast cancerQ36813907
Effects of methylglyoxal and glyoxalase I inhibition on breast cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2.Q36844345
The potential role of Akt phosphorylation in human cancersQ37137732
Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cellsQ37219099
Reactive oxygen species in cancerQ37431048
Triple-negative breast cancer: present challenges and new perspectivesQ37764168
Glyceraldehyde-3-phosphate dehydrogenase: a promising target for molecular therapy in hepatocellular carcinomaQ38042261
ROS and energy metabolism in cancer cells: alliance for fast growthQ38323297
Creatine supplementation with methylglyoxal: a potent therapy for cancer in experimental modelsQ38773677
Immunomodulation of macrophages by methylglyoxal conjugated with chitosan nanoparticles against Sarcoma-180 tumor in miceQ39039968
A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cellsQ39208002
Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivoQ39433332
Methylglyoxal induces mitochondria-dependent apoptosis in sarcomaQ39440678
Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucoseQ39451237
Activation of PI3K/Akt/IKK-alpha/NF-kappaB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetinQ39715476
AKT/NF-kappaB inhibitor xanthohumol targets cell growth and angiogenesis in hematologic malignanciesQ40083731
Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cellsQ40099129
Methylglyoxal suppresses TNF-alpha-induced NF-kappaB activation by inhibiting NF-kappaB DNA-bindingQ40110071
Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway.Q40274284
Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-kappaB activation but not GSK3beta activityQ40379454
Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysisQ40410066
Potential of traditional ayurvedic formulation, Triphala, as a novel anticancer drugQ40421234
Methylglyoxal induces apoptosis in Jurkat leukemia T cells by activating c-Jun N-terminal kinaseQ40893010
On the promine/retine theory of cell division: now and thenQ40983195
Selective inhibition of mitochondrial respiration and glycolysis in human leukaemic leucocytes by methylglyoxalQ41951110
A novel mechanism of methylglyoxal cytotoxicity in neuroglial cellsQ42445019
Resveratrol protects against methylglyoxal-induced apoptosis and disruption of embryonic development in mouse blastocystsQ42728868
Critical evaluation of toxic versus beneficial effects of methylglyoxalQ43241320
Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis processQ43702887
Morphofunctional mitochondrial response to methylglyoxal toxicity in Bufo bufo embryos.Q43733869
Advanced glycation end-products induce apoptosis of bovine retinal pericytes in culture: involvement of diacylglycerol/ceramide production and oxidative stress inductionQ44054596
Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cellsQ44358470
Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injuryQ44615951
Mitochondrial free radical production and cell signalingQ44819896
Pancratistatin: a natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosisQ46503269
Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cellsQ46613107
In vivo assessment of toxicity and pharmacokinetics of methylglyoxal. Augmentation of the curative effect of methylglyoxal on cancer-bearing mice by ascorbic acid and creatineQ46660343
Increased phosphorylation of Akt in triple-negative breast cancersQ46984077
Bcl-2-family proteins: the role of the BH3 domain in apoptosisQ47686942
P433issue9
P921main subjectreactive oxygen speciesQ424361
apoptotic processQ14599311
breast carcinomaQ18555947
P304page(s)2086-2103
P577publication date2017-04-18
P1433published inMolecular CarcinogenesisQ15724597
P1476titleInduction of mitochondrial apoptotic pathway in triple negative breast carcinoma cells by methylglyoxal via generation of reactive oxygen species
P478volume56

Reverse relations

Q47702166Glyoxalases in Urological Malignanciescites workP2860

Search more.