Design of metabolic engineering strategies for maximizing L-(-)-carnitine production by Escherichia coli. Integration of the metabolic and bioreactor levels.

scientific article published in March 2005

Design of metabolic engineering strategies for maximizing L-(-)-carnitine production by Escherichia coli. Integration of the metabolic and bioreactor levels. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BP0497583
P698PubMed publication ID15801767
P5875ResearchGate publication ID7933913

P50authorJosé Luis IborraQ42151628
Julio VeraQ47098295
Manuel CanovasQ59674047
P2093author name stringTorres NV
Sevilla A
Díaz Z
P2860cites workOptimization of tryptophan production in bacteria. Design of a strategy for genetic manipulation of the tryptophan operon for tryptophan flux maximizationQ73641807
Biotransformation of D(+)-carnitine into L(-)-carnitine by resting cells of Escherichia coli O44 K74Q77604906
A possible role of ProP, ProU and CaiT in osmoprotection of Escherichia coli by carnitineQ77743290
High-density Escherichia coli cultures for continuous L(-)-carnitine productionQ78047008
An indirect optimization method for biochemical systems: description of method and application to the maximization of the rate of ethanol, glycerol, and carbohydrate production in Saccharomyces cerevisiaeQ81660662
Involvement of coenzyme A esters and two new enzymes, an enoyl-CoA hydratase and a CoA-transferase, in the hydration of crotonobetaine to L-carnitine by Escherichia coliQ28215910
Isolation, identification, and synthesis of gamma-butyrobetainyl-CoA and crotonobetainyl-CoA, compounds involved in carnitine metabolism of E. coliQ30920819
Metabolism of citric acid production by Aspergillus niger: model definition, steady-state analysis and constrained optimization of citric acid production rateQ33913613
Identification and characterization of the caiF gene encoding a potential transcriptional activator of carnitine metabolism in Escherichia coliQ35603142
Cloning, nucleotide sequence, and expression of the Escherichia coli gene encoding carnitine dehydrataseQ36107650
Bacterial carnitine metabolismQ41351461
Modeling of the biotransformation of crotonobetaine into L-(-)-carnitine by Escherichia coli strains.Q42163041
The analysis of acyl-coenzyme A derivatives by reverse-phase high-performance liquid chromatographyQ42253701
Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coliQ42487693
Modeling, optimization and experimental assessment of continuous L-(-)-carnitine production by Escherichia coli cultures.Q42527327
CaiT of Escherichia coli, a new transporter catalyzing L-carnitine/gamma -butyrobetaine exchangeQ44090732
Effect of salt stress on crotonobetaine and D(+)-carnitine biotransformation into L(-)-carnitine by resting cells of Escherichia coli.Q44519612
Link between primary and secondary metabolism in the biotransformation of trimethylammonium compounds by escherichia coliQ44640905
Biochemical systems analysis. I. Some mathematical properties of the rate law for the component enzymatic reactions.Q53012243
Crotonobetaine reductase from Escherichia coli--a new inducible enzyme of anaerobic metabolization of L(-)-carnitine.Q54644562
Purification and properties of carnitine dehydratase from Escherichia coli--a new enzyme of carnitine metabolization.Q54728525
Isolation and characterization of the multiple charge isoforms of acyl-CoA synthetase from Escherichia coli.Q54789041
Further purification, characterization and salt activation of acyl-CoA synthetase from Escherichia coli.Q54797285
Biochemical systems analysis. II. The steady-state solutions for an n-pool system using a power-law approximationQ71337458
P433issue2
P921main subjectEscherichia coliQ25419
bioreactorQ864699
P304page(s)329-337
P577publication date2005-03-01
P1433published inBiotechnology ProgressQ15753227
P1476titleDesign of metabolic engineering strategies for maximizing L-(-)-carnitine production by Escherichia coli. Integration of the metabolic and bioreactor levels
P478volume21

Reverse relations

cites work (P2860)
Q59000297Biochemical Systems Theory: A Review
Q37380580Computational systems biology in cancer: modeling methods and applications.
Q37853843Mathematical formalisms based on approximated kinetic representations for modeling genetic and metabolic pathways
Q36958030Production of L-carnitine by secondary metabolism of bacteria
Q27664405Structural basis of Na(+)-independent and cooperative substrate/product antiport in CaiT

Search more.