| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0197-4580(02)00229-4 |
| P698 | PubMed publication ID | 12928056 |
| P2093 | author name string | Lawrence A Hansen | |
| Deborah A Shackelford | |||
| Vladislav Davydov | |||
| P2860 | cites work | Oxidants, antioxidants, and the degenerative diseases of aging | Q24561734 |
| The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations | Q24685574 | ||
| Ku, a DNA repair protein with multiple cellular functions? | Q28137885 | ||
| DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation | Q28141630 | ||
| Poly(ADP-ribose) polymerase-1 in the nervous system | Q28144839 | ||
| A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis | Q28292871 | ||
| The DNA-dependent protein kinase | Q28373950 | ||
| Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice | Q28504593 | ||
| Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice | Q28510493 | ||
| Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis | Q28610861 | ||
| Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment | Q29547294 | ||
| Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease | Q29617286 | ||
| Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells | Q29617437 | ||
| Evidence for apoptotic cell death in Alzheimer's disease. | Q53200058 | ||
| DNA strand breaks in Alzheimer's disease. | Q53231816 | ||
| Decreased base excision repair and increased helicase activity in Alzheimer's disease brain. | Q53232722 | ||
| Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work | Q57897029 | ||
| Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease | Q58006825 | ||
| Simultaneous Degradation of αII- and βII-Spectrin by Caspase 3 (CPP32) in Apoptotic Cells | Q58115643 | ||
| Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ | Q61709806 | ||
| Neocortical cell counts in normal human adult aging | Q69111257 | ||
| Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease | Q72119373 | ||
| Loss of Ref-1 protein expression precedes DNA fragmentation in apoptotic neurons | Q73067911 | ||
| Ku autoantigen is a potential major cause of nonspecific bands in electrophoretic mobility shift assays | Q73096516 | ||
| Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1. | Q31370338 | ||
| Linking DNA damage and neurodegeneration | Q34001971 | ||
| Going APE over ref-1. | Q34053099 | ||
| Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease | Q34076863 | ||
| DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? | Q34180691 | ||
| DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair | Q34868235 | ||
| DNA repair and Alzheimer's disease | Q35515165 | ||
| Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease | Q35746175 | ||
| Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death. | Q35788051 | ||
| Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease | Q36053285 | ||
| Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death | Q36366579 | ||
| Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle | Q36565894 | ||
| A simple dot-immunobinding assay for quantification of synaptophysin-like immunoreactivity in human brain | Q36760641 | ||
| Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo | Q36794903 | ||
| The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest | Q37109768 | ||
| DNA-PK, the DNA-activated protein kinase, is differentially expressed in normal and malignant human tissues | Q38324394 | ||
| Increased expression of DNA-dependent protein kinase confers resistance to adriamycin | Q38334993 | ||
| Role of oxidants in ischemic brain damage | Q40998721 | ||
| Increased immunoreactivity of brain spectrin in Alzheimer disease: a marker for synapse loss? | Q41221217 | ||
| Increased levels of DNA breaks in cerebral cortex of Alzheimer's disease patients | Q41233963 | ||
| Oxidative stress hypothesis in Alzheimer's disease | Q41482152 | ||
| Early decrease of apurinic/apyrimidinic endonuclease expression after transient focal cerebral ischemia in mice | Q41664808 | ||
| The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts | Q41710133 | ||
| Up-regulation of base excision repair activity for 8-hydroxy-2'-deoxyguanosine in the mouse brain after forebrain ischemia-reperfusion | Q42285027 | ||
| DNA replication precedes neuronal cell death in Alzheimer's disease. | Q42502934 | ||
| Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity. | Q43540745 | ||
| Immunohistochemical evidence for apoptosis in Alzheimerʼs disease | Q43561325 | ||
| Role of DNA-dependent protein kinase in neuronal survival. | Q43658606 | ||
| Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease | Q45172855 | ||
| Changes in phosphorylation of tau during ischemia and reperfusion in the rabbit spinal cord. | Q46039367 | ||
| A suicide note from Alzheimer disease neurons? | Q47697435 | ||
| In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease | Q48104646 | ||
| Phosphorylation determines two distinct species of Tau in the central nervous system | Q48261881 | ||
| RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. | Q48270446 | ||
| Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF. | Q48292696 | ||
| Increased nuclear DNA oxidation in the brain in Alzheimer's disease | Q48361470 | ||
| Expression of DNA excision-repair-cross-complementing proteins p80 and p89 in brain of patients with Down Syndrome and Alzheimer's disease | Q48406867 | ||
| Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis | Q48465161 | ||
| Expression of nuclear redox factor ref-1 in the rat hippocampus following global ischemia induced by cardiac arrest | Q48516410 | ||
| Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease. | Q48650804 | ||
| DNA damage distribution in the human brain as shown by in situ end labeling; area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology. | Q48650840 | ||
| Early decrease in dna repair proteins, Ku70 and Ku86, and subsequent DNA fragmentation after transient focal cerebral ischemia in mice | Q48859381 | ||
| 8OHdG levels in brain do not indicate oxidative DNA damage in Alzheimer's disease | Q48866003 | ||
| Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology | Q48913487 | ||
| Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity | Q48983820 | ||
| P433 | issue | 7 | |
| P921 | main subject | Alzheimer's disease | Q11081 |
| P304 | page(s) | 953-968 | |
| P577 | publication date | 2003-11-01 | |
| P1433 | published in | Neurobiology of Aging | Q7002141 |
| P1476 | title | Is DNA repair compromised in Alzheimer's disease? | |
| P478 | volume | 24 |
| Q33815578 | A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration |
| Q33990581 | APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions |
| Q36945357 | Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease |
| Q36538373 | Base excision repair in physiology and pathology of the central nervous system |
| Q39136548 | Base excision repair of oxidative DNA damage: from mechanism to disease. |
| Q36853499 | Base excision repair, aging and health span. |
| Q37122200 | Brain capacity for repair of oxidatively damaged DNA and preservation of neuronal function |
| Q35932007 | Commentary: DNA base excision repair defects in human pathologies |
| Q89977186 | Contributions of DNA Damage to Alzheimer's Disease |
| Q37558796 | DNA Repair Defects and DNA-PK in Neurodegeneration |
| Q37392155 | DNA base excision repair activities in mouse models of Alzheimer's disease |
| Q35900920 | DNA damage responses in neural cells: Focus on the telomere |
| Q34183328 | DNA repair deficiency in neurodegeneration. |
| Q64389910 | DNA-PK Deficiency in Alzheimer's Disease |
| Q33892330 | DNA-PK and P38 MAPK: A Kinase Collusion in Alzheimer's Disease? |
| Q36998015 | DNA-dependent protein kinase and DNA repair: relevance to Alzheimer's disease |
| Q36059507 | Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment |
| Q36260240 | Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients. |
| Q47351811 | Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons. |
| Q35924071 | Divide and die: cell cycle events as triggers of nerve cell death. |
| Q91911156 | Evaluation of antioxidant and antimutagenic activities of aluminum chloride |
| Q34345211 | Evidence of altered DNA integrity in the brain regions of suicidal victims of Bipolar Depression |
| Q51825149 | Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic. |
| Q34451972 | Genome-wide DNA methylation and gene expression analyses of monozygotic twins discordant for intelligence levels |
| Q37133171 | Global analysis of phosphorylation of tau by the checkpoint kinases Chk1 and Chk2 in vitro |
| Q37512952 | Human apurinic/apyrimidinic endonuclease 1. |
| Q37140173 | Mitochondrial DNA repair in aging and disease |
| Q34082641 | New evidence on iron, copper accumulation and zinc depletion and its correlation with DNA integrity in aging human brain regions |
| Q28235590 | Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells |
| Q33570892 | Oxidative damage and defective DNA repair is linked to apoptosis of migrating neurons and progenitors during cerebral cortex development in Ku70-deficient mice |
| Q35957287 | Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases. |
| Q28581799 | Rapid phosphorylation of histone H2A.X following ionotropic glutamate receptor activation |
| Q33980306 | Tau Ser262 phosphorylation is critical for Abeta42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease |
| Q41661210 | The Emerging Role of GLP-1 Receptors in DNA Repair: Implications in Neurological Disorders |
| Q33609187 | The many functions of APE1/Ref-1: not only a DNA repair enzyme |
| Q30434808 | Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein |
Search more.