Pharmacokinetics and penetration of linezolid into inflamed soft tissue in diabetic foot infections

scientific article published on 25 July 2008

Pharmacokinetics and penetration of linezolid into inflamed soft tissue in diabetic foot infections is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00228-008-0531-5
P698PubMed publication ID18654767

P2093author name stringG Haase
W Schareck
B Drewelow
A Pietsch
M Sass
R Mundkowski
J Majcher-Peszynska
S Klammt
P2860cites workLinezolid tissue penetration and serum activity against strains of methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibility in diabetic patients with foot infectionsQ80730925
Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapyQ24519008
Pharmacokinetic and pharmacodynamic profile of linezolid in healthy volunteers and patients with Gram-positive infectionsQ33347869
Linezolid versus vancomycin in treatment of complicated skin and soft tissue infectionsQ33836490
Penetration of linezolid into soft tissues of healthy volunteers after single and multiple doses.Q33836578
Clinical efficacy and antimicrobial pharmacodynamics.Q33873989
Intrapulmonary pharmacokinetics of linezolidQ34106719
In vivo pharmacodynamics of a new oxazolidinone (linezolid)Q34142754
Treating foot infections in diabetic patients: a randomized, multicenter, open-label trial of linezolid versus ampicillin-sulbactam/amoxicillin-clavulanateQ34284305
Diagnosis and treatment of diabetic foot infectionsQ34357233
Pharmacokinetics of linezolid in subjects with renal dysfunctionQ35685516
Tissue pharmacokinetics of levofloxacin in human soft tissue infectionsQ35826148
Bacteriology of moderate-to-severe diabetic foot infections and in vitro activity of antimicrobial agentsQ36098587
Microdialysis for in vivo pharmacokinetic/pharmacodynamic characterization of anti-infective drugsQ36220885
Pharmacokinetics and tissue penetration of linezolid following multiple oral dosesQ39477515
Uptake and intracellular activity of linezolid in human phagocytes and nonphagocytic cells.Q39671242
Pharmacokinetics of unbound linezolid in plasma and tissue interstitium of critically ill patients after multiple dosing using microdialysisQ41473712
Pharmacokinetic/pharmacodynamic factors influencing emergence of resistance to linezolid in an in vitro modelQ42846091
Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shockQ43541038
Successful treatment of vancomycin-resistant Enterococcus meningitis with linezolidQ43689994
Linezolid levels in pancreatic secretionsQ43815773
Penetration of linezolid into bone, fat, muscle and haematoma of patients undergoing routine hip replacementQ44049240
Linezolid penetration into osteo-articular tissuesQ44198710
Pharmacokinetics, toxicokinetics, distribution, metabolism and excretion of linezolid in mouse, rat and dog.Q44206806
Methicillin-resistant Staphylococcus aureus in the diabetic foot clinic: a worsening problemQ44311731
Target site penetration of fosfomycin in critically ill patientsQ44385715
Intrapulmonary penetration of linezolidQ44440587
Aqueous and vitreous penetration of linezolid (Zyvox) after oral administrationQ44921565
Diabetic foot infections. Bacteriology and activity of 10 oral antimicrobial agents against bacteria isolated from consecutive cases.Q45981790
Pharmacokinetics and intrapulmonary concentrations of linezolid administered to critically ill patients with ventilator-associated pneumoniaQ46589068
Prevalence of methicillin-resistant Staphylococcus aureus in infected and uninfected diabetic foot ulcersQ46915090
Determination of antibiotic drug concentrations in circulating human blood by means of solid phase micro-extractionQ48568291
Effects of hyperglycemia on interdigestive gastrointestinal motility in humans.Q51592642
Empirical therapy for diabetic foot infections: are there clinical clues to guide antibiotic selection?Q57543717
Hyperglycaemia and absorption of sulphonylurea drugsQ69371278
Determination of linezolid in plasma by reversed-phase high-performance liquid chromatographyQ73513895
Plasma and tissue pharmacokinetics of cefpirome in patients with sepsisQ74492356
P433issue11
P921main subjectpharmacokineticsQ323936
linezolidQ411377
P304page(s)1093-1100
P577publication date2008-07-25
P1433published inEuropean Journal of Clinical PharmacologyQ1376707
P1476titlePharmacokinetics and penetration of linezolid into inflamed soft tissue in diabetic foot infections
P478volume64

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cites work (P2860)
Q38070154An evidence-based review of linezolid for the treatment of methicillin-resistant Staphylococcus aureus (MRSA): place in therapy
Q36620071Applicability of a Single Time Point Strategy for the Prediction of Area Under the Concentration Curve of Linezolid in Patients: Superiority of Ctrough- over Cmax-Derived Linear Regression Models
Q39278957Clinical Determinants of Target Non-Attainment of Linezolid in Plasma and Interstitial Space Fluid: A Pooled Population Pharmacokinetic Analysis with Focus on Critically Ill Patients.
Q47611899Clinical Pharmacokinetics and Pharmacodynamics of Oxazolidinones
Q33397069Correlation between serum linezolid concentration and the development of thrombocytopenia
Q38283321Determination of tissue penetration and pharmacokinetics of linezolid in patients with diabetic foot infections using in vivo microdialysis
Q37869258Linezolid pharmacokinetics and pharmacodynamics in clinical treatment
Q37788206Methicillin-Resistant Staphylococcus aureus in Diabetic Foot Infections
Q53853180Pharmacokinetics and penetration of moxifloxacin into infected diabetic foot tissue in a large diabetic patient cohort
Q35838594Pharmacokinetics of antiretrovirals in mucosal tissue
Q47218572Population pharmacokinetic analysis of linezolid in low body weight patients with renal dysfunction.
Q36894442Unwanted baggage

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