scholarly article | Q13442814 |
P50 | author | Serena Carra | Q55136801 |
P2093 | author name string | Jacques Landry | |
Herman Lambert | |||
Aura T Chávez Zobel | |||
Mitchel Sivilotti | |||
P2860 | cites work | Mechanisms for regulation of Hsp70 function by Hsp40 | Q24563232 |
The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10 | Q24563241 | ||
Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27 | Q24646796 | ||
Crystal structure of a small heat-shock protein | Q27765131 | ||
Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity | Q28143597 | ||
Molecular chaperones in the cytosol: from nascent chain to folded protein | Q28205903 | ||
Impairment of the ubiquitin-proteasome system by protein aggregation | Q29614556 | ||
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases | Q29616535 | ||
Protein degradation and protection against misfolded or damaged proteins | Q29618400 | ||
Alpha-crystallin can function as a molecular chaperone | Q29618672 | ||
Formic acid dissolves aggregates of an N-terminal huntingtin fragment containing an expanded polyglutamine tract: applying to quantification of protein components of the aggregates | Q31460493 | ||
Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone | Q33858200 | ||
A small heat shock protein stably binds heat-denatured model substrates and can maintain a substrate in a folding-competent state | Q33886098 | ||
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy | Q34023072 | ||
Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases | Q34142252 | ||
From the cradle to the grave: molecular chaperones that may choose between folding and degradation | Q34400939 | ||
Polyglutamine fibrillogenesis: the pathway unfolds | Q34466014 | ||
Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease | Q35084195 | ||
Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils | Q35169533 | ||
Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain | Q35416428 | ||
CHIP: a link between the chaperone and proteasome systems | Q35759085 | ||
The sperm outer dense fiber protein is the 10th member of the superfamily of mammalian small stress proteins | Q37490527 | ||
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease | Q43874109 | ||
Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy | Q43903236 | ||
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo | Q45294913 | ||
Molecular chaperones and the stress of oncogenesis | Q47785215 | ||
P433 | issue | 12 | |
P921 | main subject | molecular chaperones | Q422496 |
P304 | page(s) | 1659-1669 | |
P577 | publication date | 2005-05-06 | |
P1433 | published in | Human Molecular Genetics | Q2720965 |
P1476 | title | HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells | |
P478 | volume | 14 |
Q38638620 | A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8. |
Q34427456 | Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3). |
Q37459887 | Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection |
Q46253811 | Analysis of HspB1 (Hsp27) Oligomerization and Phosphorylation Patterns and Its Interaction with Specific Client Polypeptides |
Q37824973 | Analyzing the aggregation of polyglutamine-expansion proteins and its modulation by molecular chaperones |
Q37901022 | Autophagy, protein aggregation and hyperthermia: a mini-review |
Q38973305 | BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch. |
Q28088321 | BAG3: a new player in the heart failure paradigm |
Q26824841 | Charcot-Marie-Tooth disease and intracellular traffic |
Q37107539 | Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy. |
Q33358423 | Computational analysis of the human HSPH/HSPA/DNAJ family and cloning of a human HSPH/HSPA/DNAJ expression library |
Q34451159 | Conformational changes resulting from pseudophosphorylation of mammalian small heat shock proteins--a two-hybrid study |
Q42392887 | Cystathionine beta-synthase mutations: effect of mutation topology on folding and activity |
Q38093166 | Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders. |
Q37342284 | Differential autophagy power in the spinal cord and muscle of transgenic ALS mice. |
Q47265982 | Downregulation of heat shock protein B8 decreases osteogenic differentiation potential of dental pulp stem cells during in vitro proliferation |
Q39299545 | Effect of Geranylgeranylacetone on Ultraviolet Radiation Type B-Induced Cataract in Heat-Shock Transcription Factor 1 Heterozygous Mouse |
Q36296410 | H11/HspB8 and Its Herpes Simplex Virus Type 2 Homologue ICP10PK Share Functions That Regulate Cell Life/Death Decisions and Human Disease |
Q34298044 | HSPA1A-independent suppression of PARK2 C289G protein aggregation by human small heat shock proteins |
Q36856938 | HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles. |
Q24313299 | HSPB7 is a SC35 speckle resident small heat shock protein |
Q39655631 | HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones |
Q47147911 | HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons |
Q53530930 | HSPB8 and the Cochaperone BAG3 Are Highly Expressed During the Synthetic Phase of Rat Myometrium Programming During Pregnancy. |
Q36550110 | Heat shock protein 27: its potential role in vascular disease |
Q28272905 | Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update |
Q30392284 | Heat shock proteins: cellular and molecular mechanisms in the central nervous system |
Q40050938 | HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy. |
Q48626057 | HspB8 expression in brain tissue after cerebral ischemic reperfusion and atorvastatin intervention in Sprague-Dawley rats |
Q26999062 | Human small heat shock proteins: protein interactomes of homo- and hetero-oligomeric complexes: an update |
Q34333825 | Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases. |
Q28115657 | Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction |
Q36259341 | Induction of Hsp22 (HspB8) by estrogen and the metalloestrogen cadmium in estrogen receptor-positive breast cancer cells |
Q38840491 | Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases. |
Q53322022 | Inhibition of α-synuclein aggregation by small heat shock proteins. |
Q40223755 | Interaction of mammalian Hsp22 with lipid membranes |
Q37947562 | Large potentials of small heat shock proteins |
Q47362679 | Measurement of Chaperone-Mediated Effects on Polyglutamine Protein Aggregation by the Filter Trap Assay |
Q36577237 | Mechanisms of disease: a molecular genetic update on hereditary axonal neuropathies |
Q40084012 | Modulation of polyglutamine inclusion formation by the Hsp70 chaperone machine. |
Q34979557 | Molecular chaperones antagonize proteotoxicity by differentially modulating protein aggregation pathways |
Q36507144 | Molecular genetics of autosomal-dominant axonal Charcot-Marie-Tooth disease |
Q39694541 | Mutant HSPB8 causes motor neuron-specific neurite degeneration. |
Q30364996 | Mutations in HSPB8 causing a new phenotype of distal myopathy and motor neuropathy |
Q60044498 | Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks |
Q89860827 | Neuromuscular Diseases Due to Chaperone Mutations: A Review and Some New Results |
Q92557970 | New family with HSPB8-associated autosomal dominant rimmed vacuolar myopathy |
Q37288545 | Pathology-dependent effects linked to small heat shock proteins expression: an update |
Q36900533 | Pharmacoinformatic and molecular docking studies reveal potential novel antidepressants against neurodegenerative disorders by targeting HSPB8. |
Q45288723 | Polyglutamine aggregation in Huntington's disease and spinocerebellar ataxia type 3: similar mechanisms in aggregate formation |
Q33662149 | Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells |
Q30862326 | Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desmin-related cardiomyopathy |
Q45735441 | Protein Misfolding and Aggregation as a Therapeutic Target for Polyglutamine Diseases |
Q38108621 | Protein interactomes of three stress inducible small heat shock proteins: HspB1, HspB5 and HspB8. |
Q37843794 | Recent advances in the genetics of hereditary axonal sensory-motor neuropathies type 2. |
Q33356801 | Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice |
Q34095190 | Salvianolate increases heat shock protein expression in a cerebral ischemia-reperfusion injury model |
Q26766007 | Small Heat Shock Proteins and Distal Hereditary Neuropathies |
Q33935094 | Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation. |
Q36665470 | Specific protein homeostatic functions of small heat-shock proteins increase lifespan. |
Q37299616 | Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110 |
Q38019159 | Targeting Huntington's disease through histone deacetylases |
Q37774037 | Targeting histone deacetylases for the treatment of Huntington's disease. |
Q51291235 | The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins. |
Q49139873 | The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases. |
Q92711469 | The Regulation of the Small Heat Shock Protein B8 in Misfolding Protein Diseases Causing Motoneuronal and Muscle Cell Death |
Q33819258 | The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases. |
Q39416466 | The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease |
Q38634366 | The Role of the Protein Quality Control System in SBMA. |
Q36283359 | The Social Amoeba Dictyostelium discoideum Is Highly Resistant to Polyglutamine Aggregation |
Q37623715 | The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity. |
Q24336905 | The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities |
Q34227679 | The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells. |
Q38728380 | The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases. |
Q37705845 | The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells |
Q36670771 | Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases |