scholarly article | Q13442814 |
P50 | author | James Driscoll | Q44422718 |
P2093 | author name string | Donglu Zhang | |
S Cyrus Khojasteh | |||
Peter W Fan | |||
Jason S Halladay | |||
P2860 | cites work | The species-dependent metabolism of efavirenz produces a nephrotoxic glutathione conjugate in rats | Q43927642 |
Metabolism of MRX-I, a novel antibacterial oxazolidinone, in humans: the oxidative ring opening of 2,3-Dihydropyridin-4-one catalyzed by non-P450 enzymes | Q46298070 | ||
Elucidation of the mechanism of ribose conjugation in a pyrazole-containing compound in rodent liver | Q46355950 | ||
Excretion, metabolism, and pharmacokinetics of 1-(8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl)-4-(ethylamino)piperidine-4-carboxamide, a selective cannabinoid receptor antagonist, in healthy male volunteers | Q50151544 | ||
Metabolism of furans in vitro: ipomeanine and 4-ipomeanol. | Q53586817 | ||
Biocatalytic Characterization of Human FMO5: Unearthing Baeyer–Villiger Reactions in Humans | Q56879308 | ||
Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr | Q27650104 | ||
Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability | Q27703141 | ||
The role of aldehyde oxidase in drug metabolism | Q28259834 | ||
Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery | Q28293711 | ||
Gamma-glutamyl transpeptidase-deficient mice are resistant to the nephrotoxic effects of cisplatin | Q28363414 | ||
Oxidative metabolism of a quinoxaline derivative by xanthine oxidase in rodent plasma | Q34027786 | ||
Role of NADase in virulence in experimental invasive group A streptococcal infection | Q34033126 | ||
New facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases | Q34042969 | ||
The resurgence of covalent drugs | Q34174891 | ||
Chemical-induced nephrotoxicity mediated by glutathione S-conjugate formation | Q34421632 | ||
Human flavin-containing monooxygenases | Q34482959 | ||
Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity | Q34690068 | ||
Subunit structure and isozymic forms of gamma-glutamyl transpeptidase | Q35015390 | ||
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834 | Q35600249 | ||
Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios | Q35860313 | ||
Some distinctions between flavin-containing and cytochrome P450 monooxygenases | Q36235997 | ||
Expression of gamma-glutamyltransferase in cancer cells and its significance in drug resistance | Q36319665 | ||
Drug-metabolizing ability of molybdenum hydroxylases | Q36479826 | ||
Cysteine cathepsins: multifunctional enzymes in cancer | Q36600996 | ||
Antibody-drug conjugates for cancer therapy | Q37184293 | ||
Cathepsins and their involvement in immune responses | Q37774592 | ||
Antibody-drug conjugates: an emerging concept in cancer therapy | Q38200071 | ||
Rho regulation: DLC proteins in space and time | Q38427809 | ||
Design of a paclitaxel prodrug conjugate for active targeting of an enzyme upregulated in breast cancer cells | Q38993094 | ||
Cathepsin B cleavable novel prodrug Ac-Phe-Lys-PABC-ADM enhances efficacy at reduced toxicity in treating gastric cancer peritoneal carcinomatosis: an experimental study | Q39456682 | ||
γ-Glutamyl transpeptidase: catalytic, structural and functional aspects | Q40085819 | ||
NAD hydrolysis: chemical and enzymatic mechanisms | Q40616474 | ||
Role of CysteineS-Conjugate β-Lyase in the Metabolism of Cisplatin | Q40647370 | ||
Significant species difference in amide hydrolysis of GDC-0834, a novel potent and selective Bruton's tyrosine kinase inhibitor | Q42730808 | ||
Formation of a quinoneimine intermediate of 4-fluoro-N-methylaniline by FMO1: carbon oxidation plus defluorination. | Q43108660 | ||
Relationship between physicochemical and osteotropic properties of bisphosphonic derivatives: rational design for osteotropic drug delivery system (ODDS). | Q43682875 | ||
Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin | Q43918793 | ||
P433 | issue | 8 | |
P304 | page(s) | 1253-1261 | |
P577 | publication date | 2016-04-26 | |
P1433 | published in | Drug Metabolism and Disposition | Q1261140 |
P1476 | title | Going Beyond Common Drug Metabolizing Enzymes: Case Studies of Biotransformation Involving Aldehyde Oxidase, γ-Glutamyl Transpeptidase, Cathepsin B, Flavin-Containing Monooxygenase, and ADP-Ribosyltransferase | |
P478 | volume | 44 |
Q39016532 | An overview of aldehyde oxidase: an enzyme of emerging importance in novel drug discovery |
Q40097312 | Metabolism of F18, a Derivative of Calanolide A, in Human Liver Microsomes and Cytosol |
Q39411224 | Toward an Understanding of Structural Insights of Xanthine and Aldehyde Oxidases: An Overview of their Inhibitors and Role in Various Diseases. |
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