KLF5 and hhLIM cooperatively promote proliferation of vascular smooth muscle cells

scientific article published on 15 May 2012

KLF5 and hhLIM cooperatively promote proliferation of vascular smooth muscle cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S11010-012-1332-9
P698PubMed publication ID22584587

P2093author name stringYan Liu
Bin Zheng
Jin-kun Wen
Hui-jing Shi
Sui-bing Miao
P2860cites workPro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modificationQ39908760
hhLIM is a novel F-actin binding protein involved in actin cytoskeleton remodelingQ40004030
Human heart LIM protein activates atrial-natriuretic-factor gene expression by interacting with the cardiac-restricted transcription factor Nkx2.5.Q40069876
hhLIM is involved in cardiomyogenesis of embryonic stem cellsQ40314871
Kruppel-like factor 5 shows proliferation-specific roles in vascular remodeling, direct stimulation of cell growth, and inhibition of apoptosisQ43148405
Altered PDGF-BB-induced p38 MAP kinase activation in diabetic vascular smooth muscle cells: roles of protein kinase C-deltaQ45042440
PDGF-BB regulates p27 expression through ERK-dependent RNA turn-over in vascular smooth muscle cells.Q46491327
Drosophila double-parked is sufficient to induce re-replication during development and is regulated by cyclin E/CDK2.Q52087804
Leptin-induced vascular smooth muscle cell proliferation via regulating cell cycle, activating ERK1/2 and NF-kappaB.Q53324906
Mammalian Krüppel-Like Factors in Health and DiseasesQ24612560
Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domainQ24648562
MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formationQ24650539
Krüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cellsQ28566073
ATRA activates and PDGF-BB represses the SM22α promoter through KLF4 binding to, or dissociating from, its cis-DNA elementsQ28571337
Synthetic retinoid Am80 inhibits interaction of KLF5 with RAR alpha through inducing KLF5 dephosphorylation mediated by the PI3K/Akt signaling in vascular smooth muscle cellsQ28574855
Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cellsQ30441514
Vascular smooth muscle growth: autocrine growth mechanismsQ34294052
Resveratrol inhibits TNF-alpha-induced proliferation and matrix metalloproteinase expression in human vascular smooth muscle cellsQ34562979
Transforming growth factor beta up-regulates cysteine-rich protein 2 in vascular smooth muscle cells via activating transcription factor 2Q36678525
Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cellsQ37258607
TGF-beta through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formationQ37298372
Vascularizing the heartQ37833832
Roscovitine inhibits ERK1/2 activation induced by angiotensin II in vascular smooth muscle cellsQ38295283
A novel roscovitine derivative potently induces G1-phase arrest in platelet-derived growth factor-BB-activated vascular smooth muscle cellsQ39776539
Angiotensin II stimulates KLF5 phosphorylation and its interaction with c-Jun leading to suppression of p21 expression in vascular smooth muscle cellsQ39821441
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)185-194
P577publication date2012-05-15
P1433published inMolecular and Cellular BiochemistryQ1573176
P1476titleKLF5 and hhLIM cooperatively promote proliferation of vascular smooth muscle cells
P478volume367

Reverse relations

cites work (P2860)
Q43159975Angiotensin II Downregulates MicroRNA-145 to Regulate Kruppel-like Factor 4 and Myocardin Expression in Human Coronary Arterial Smooth Muscle Cells under High Glucose Conditions
Q47676828Krüppel-like factors and vascular wall homeostasis.
Q36447499ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer
Q45731738Methylation and expression of RECK, P53 and RUNX genes in patients with esophageal cancer
Q91911696Pioglitazone protects blood vessels through inhibition of the apelin signaling pathway by promoting KLF4 expression in rat models of T2DM
Q42489975SUMOylation of KLF4 acts as a switch in transcriptional programs that control VSMC proliferation
Q33826984Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system
Q41098266Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas
Q27022848The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformation

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