Pharmacogenomics of importance for paclitaxel chemotherapy

scientific article published in June 2008

Pharmacogenomics of importance for paclitaxel chemotherapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2217/14622416.9.6.671
P698PubMed publication ID18518845
P5875ResearchGate publication ID51395531

P50authorHenrik GréenQ38544926
P2860cites workmdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapyQ27824862
Genetic contribution to variable human CYP3A-mediated metabolismQ28212042
Pharmacokinetics of paclitaxel in ovarian cancer patients and genetic polymorphisms of CYP2C8, CYP3A4, and MDR1.Q33366351
Association of ABCB1 genotypes with paclitaxel-mediated peripheral neuropathy and neutropeniaQ35148088
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestineQ36031211
Taxol: a novel investigational antimicrotubule agentQ37593661
Multidrug resistance gene-1 is a useful predictor of Paclitaxel-based chemotherapy for patients with ovarian cancerQ40715119
Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolismQ40760221
Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.Q40773486
Identification of functionally variant MDR1 alleles among European Americans and African AmericansQ43705904
Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 allelesQ43947585
Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian CancerQ46958963
Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samplesQ47872729
Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics.Q50641149
ABCB1 G1199A polymorphism and ovarian cancer response to paclitaxel.Q50666167
beta-Tubulin mutations in ovarian cancer using single strand conformation analysis-risk of false positive results from paraffin embedded tissues.Q50762508
Genetic variation in ABCB1 influences paclitaxel pharmacokinetics in Japanese patients with ovarian cancer.Q51938857
Impact of the haplotype CYP3A4*16B harboring the Thr185Ser substitution on paclitaxel metabolism in Japanese patients with cancer.Q54588624
P433issue6
P921main subjectpaclitaxelQ423762
chemotherapyQ974135
pharmacogenomicsQ1152227
P304page(s)671-674
P577publication date2008-06-01
P1433published inPharmacogenomicsQ15724625
P1476titlePharmacogenomics of importance for paclitaxel chemotherapy
P478volume9

Reverse relations

cites work (P2860)
Q33818738Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines.
Q45244167Evaluation of vitamin B12 effects on DNA damage induced by paclitaxel
Q37346198Pharmaco(epi)genomics in ovarian cancer
Q47241273Pharmacogenetics of response to neoadjuvant paclitaxel treatment for locally advanced breast cancer.
Q36216741The ABCB1 3435 T allele does not increase the risk of paclitaxel-induced neurotoxicity

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