Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and emesis over multiple cycles of moderately emetogenic chemotherapy.

scientific article published in October 2005

Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and emesis over multiple cycles of moderately emetogenic chemotherapy. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/CNCR.21343
P698PubMed publication ID16104039
P5875ResearchGate publication ID7656683

P50authorKevin J HorganQ56797386
Jørn HerrstedtQ93260680
Hyman B MussQ104758257
Paul J HeskethQ114369492
Harry RaftopoulosQ114369494
Steven M GrunbergQ114369495
Munir GabrielQ114369496
Carolyn M HustadQ114369497
Franck SkobierandaQ114369498
P2093author name stringAnthony Rodgers
Peter D Eisenberg
David G Warr
Aprepitant Moderately Emetogenic Chemotherapy Study Group
P2860cites workRecommendations for the use of antiemetics: evidence-based, clinical practice guidelines. American Society of Clinical OncologyQ33880234
Delayed emesis: moderately emetogenic chemotherapyQ35953416
Acute emesis: moderately emetogenic chemotherapyQ35964110
Consensus proposals for the prevention of acute and delayed vomiting and nausea following high-emetic-risk chemotherapy.Q35964114
Evaluation of new antiemetic agents and definition of antineoplastic agent emetogenicity--an update.Q35984417
Granisetron compared with prednisolone plus metopimazine as anti-emetic prophylaxis during multiple cycles of moderately emetogenic chemotherapyQ36617964
Analysis of cumulative probabilities shows that the efficacy of 5HT3 antagonist prophylaxis is not maintainedQ36799686
Proposal for classifying the acute emetogenicity of cancer chemotherapyQ41314646
Ondansetron plus metopimazine compared with ondansetron plus metopimazine plus prednisolone as antiemetic prophylaxis in patients receiving multiple cycles of moderately emetogenic chemotherapyQ43562737
Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting. Results from a randomized, double-blind, placebo-controlled trial in Latin AmericaQ44464294
The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin--the Aprepitant Protocol 052 StQ44618271
The oral NK(1) antagonist, aprepitant, given with standard antiemetics provides protection against nausea and vomiting over multiple cycles of cisplatin-based chemotherapy: a combined analysis of two randomised, placebo-controlled phase III clinicalQ44744702
Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer after moderately emetogenic chemotherapyQ46443858
Antiemetic activity of high doses of metoclopramide combined with methylprednisolone versus metoclopramide alone in cisplatin-treated cancer patients: a randomized double-blind trial of the Italian Oncology Group for Clinical Research.Q52612776
Comparison of dexamethasone and ondansetron in the prophylaxis of emesis induced by moderately emetogenic chemotherapyQ61868395
Ondansetron compared with metoclopramide in the control of emesis and quality of life during repeated chemotherapy for breast cancerQ67547487
The pattern of emesis following high-dose cyclophosphamide and the anti-emetic efficacy of ondansetronQ71698818
ESMO Recommendations for prophylaxis of chemotherapy-induced nausea and vomiting (NV)Q74585768
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectchemotherapyQ974135
preventionQ1717246
P304page(s)1548-1555
P577publication date2005-10-01
P1433published inCancerQ326041
P1476titleEfficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and emesis over multiple cycles of moderately emetogenic chemotherapy
P478volume104

Reverse relations

cites work (P2860)
Q84640968Acute emesis: moderately emetogenic chemotherapy
Q53239014Addition of aprepitant improves protection against cisplatin-induced emesis when a conventional anti-emetic regimen fails.
Q34588516An update on palonosetron hydrochloride for the treatment of radio/chemotherapy-induced nausea and vomiting
Q86928599Anti-emetics in paediatric patients receiving chemotherapy
Q37355479Antiemetic therapy options for chemotherapy-induced nausea and vomiting in breast cancer patients.
Q37039597Antiemetics: an update and the MASCC guidelines applied in clinical practice
Q36673972Aprepitant for prevention of nausea and vomiting secondary to high-dose cyclophosphamide administered to patients undergoing autologous peripheral blood stem cells mobilization: a phase II trial.
Q45163008Aprepitant triple therapy for the prevention of chemotherapy-induced nausea and vomiting following high-dose cisplatin in Chinese patients: a randomized, double-blind, placebo-controlled phase III trial
Q37589613Aprepitant: a review of its use in the prevention of nausea and vomiting
Q34450534Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting.
Q36925594Blocking neurogenic inflammation for the treatment of acute disorders of the central nervous system.
Q36064834Chemotherapy-Induced Nausea and Vomiting: Time for More Emphasis on Nausea?
Q40143472Choice of study endpoint significantly impacts the results of breast cancer trials evaluating chemotherapy-induced nausea and vomiting
Q38123245Cisplatin : an old drug with a newfound efficacy -- from mechanisms of action to cytotoxicity
Q89260280Corticosteroids, the oldest agent in the prevention of chemotherapy-induced nausea and vomiting: What about the guidelines?
Q46927060Cost-effectiveness analysis of aprepitant in the prevention of chemotherapy-induced nausea and vomiting in Belgium
Q37091366Cost-effectiveness of an aprepitant regimen for prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer in the UK
Q37609798Current pharmacotherapy for chemotherapy-induced nausea and vomiting in cancer patients
Q34289628Daily palonosetron is superior to ondansetron in the prevention of delayed chemotherapy-induced nausea and vomiting in patients with acute myelogenous leukemia
Q41644259Defining optimal control of chemotherapy-induced nausea and vomiting-based on patients' experience.
Q30235971Delayed Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Incidence, and Current Management
Q37857329Development of aprepitant, the first neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting
Q40866626Efficacy and safety of fosaprepitant for the prevention of nausea and emesis during 5 weeks of chemoradiotherapy for cervical cancer (the GAND-emesis study): a multinational, randomised, placebo-controlled, double-blind, phase 3 trial.
Q44470627Efficacy of the neurokinin-1 receptor antagonist aprepitant in children with cyclical vomiting syndrome
Q84206278Evaluation of risk factors predictive of nausea and vomiting with current standard-of-care antiemetic treatment: analysis of phase 3 trial of aprepitant in patients receiving adriamycin-cyclophosphamide-based chemotherapy
Q37902946Fall in plasma ghrelin concentrations after cisplatin-based chemotherapy in esophageal cancer patients
Q92993034Fixed combination of oral NEPA (netupitant-palonosetron) for the prevention of acute and delayed chemotherapy-induced nausea and vomiting in patients receiving multiple cycles of chemotherapy: Efficacy data from 2 randomized, double-blind phase III
Q34239808Fosaprepitant and aprepitant: an update of the evidence for their place in the prevention of chemotherapy-induced nausea and vomiting
Q37982438Fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting
Q37672351Fosaprepitant-induced phlebitis: a focus on patients receiving doxorubicin/cyclophosphamide therapy
Q39653943Infusion site adverse events in breast cancer patients receiving highly emetic chemotherapy with prophylactic anti-emetic treatment with aprepitant and fosaprepitant: A retrospective comparison
Q42786722Management of chemotherapy-induced nausea and vomiting
Q37660556NEPA, a fixed oral combination of netupitant and palonosetron, improves control of chemotherapy-induced nausea and vomiting (CINV) over multiple cycles of chemotherapy: results of a randomized, double-blind, phase 3 trial versus oral palonosetron
Q36920404Nanomedicines in the treatment of emesis during chemotherapy: focus on aprepitant
Q90435566Netupitant/palonosetron (NEPA) and dexamethasone for prevention of emesis in breast cancer patients receiving adjuvant anthracycline plus cyclophosphamide: a multi-cycle, phase II study
Q46336740Palonosetron and prednisolone for the prevention of nausea and emesis during fractionated radiotherapy and 5 cycles of concomitant weekly cisplatin-a phase II study.
Q36478194Personalized Estimate of Chemotherapy-Induced Nausea and Vomiting: Development and External Validation of a Nomogram in Cancer Patients Receiving Highly/Moderately Emetogenic Chemotherapy.
Q59104644Phase II, open label, randomized comparative trial of ondansetron alone versus the combination of ondansetron and aprepitant for the prevention of nausea and vomiting in patients with hematologic malignancies receiving regimens containing high-dose c
Q38290777Placebo interventions for nausea: a systematic review
Q37636064Prevention of chemotherapy induced nausea and vomiting: a focus on aprepitant
Q36823546Prevention of chemotherapy-induced nausea and vomiting: focus on fosaprepitant
Q51466468Prospective evaluation of the incidence of delayed nausea and vomiting in patients with colorectal cancer receiving oxaliplatin-based chemotherapy.
Q57070792Randomized, double-blind trial comparing the antiemetic effect of tropisetron plus metopimazine with tropisetron plus placebo in patients receiving multiple cycles of multiple-day cisplatin-based chemotherapy
Q37104814Randomized, placebo-controlled, pilot study evaluating aprepitant single dose plus palonosetron and dexamethasone for the prevention of acute and delayed chemotherapy-induced nausea and vomiting
Q58828834Results of a 7-day aprepitant schedule for the prevention of nausea and vomiting in 5-day cisplatin-based germ cell tumor chemotherapy
Q38789806Rolapitant for the prevention of delayed nausea and vomiting over initial and repeat courses of emetogenic chemotherapy
Q50661502SEOM clinical guidelines for the treatment of antiemetic prophylaxis in cancer patients receiving chemotherapy
Q85708178SEOM guide to antiemetic prophylaxis in cancer patients treated with chemotherapy 2013
Q44165565Safety and efficacy of aprepitant, ramosetron, and dexamethasone for chemotherapy-induced nausea and vomiting in patients with ovarian cancer treated with paclitaxel/carboplatin
Q37854702Safety evaluation of aprepitant for the prevention of chemotherapy-induced nausea and vomiting
Q38109245Safety of neurokinin-1 receptor antagonists
Q36607177Substance P as a novel anti-obesity target
Q37638682Tachykinin receptor antagonists in clinical trials
Q36548740The neurokinin1 receptor antagonist aprepitant as an antiemetic for moderately emetogenic chemotherapy
Q37503489Treatment of Nausea and Vomiting During Chemotherapy.
Q38060202Use of PD biomarkers to drive dose selection and early clinical decision making
Q34417851Use of granisetron transdermal system in the prevention of chemotherapy-induced nausea and vomiting: a review

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