Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases

scientific article published on 16 August 2005

Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M503912200
P698PubMed publication ID16105844
P5875ResearchGate publication ID7654543

P2093author name stringHiroshi Tokumitsu
Naohito Nozaki
Hiroyuki Inuzuka
Naoya Hatano
Ryoji Kobayashi
Tohru Ichimura
Shigeyuki Yokokura
Yuka Sueyoshi
P2860cites workActivation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5Q24290618
Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon proteaseQ24297876
Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction moduleQ24313034
Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin IQ24633860
CRMP-2 regulates polarized Numb-mediated endocytosis for axon growthQ27863772
Protein kinase C mu is negatively regulated by 14-3-3 signal transduction proteinsQ28139665
Phosphorylation screening identifies translational initiation factor 4GII as an intracellular target of Ca(2+)/calmodulin-dependent protein kinase IQ28204846
Ca(2+)/CaM-dependent kinases: from activation to functionQ28206372
Characterization of the mechanism of regulation of Ca2+/ calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinaseQ28279720
Identification of the site of interaction of the 14-3-3 protein with phosphorylated tryptophan hydroxylaseQ28285080
The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domainsQ28289472
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)Q28297419
Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fateQ28569216
Cloning, characterization and expression of two alternatively splicing isoforms of Ca2+/calmodulin-dependent protein kinase I gamma in the rat brainQ28575226
Differential regulatory mechanism of Ca2+/calmodulin-dependent protein kinase kinase isoformsQ28583894
Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK)Q28587761
Progenitor cell maintenance requires numb and numblike during mouse neurogenesisQ28594835
Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding siteQ28610026
Active and inactive protein kinases: structural basis for regulationQ29616320
Cloning of a calmodulin kinase I homologue from Schizosaccharomyces pombeQ30830000
Regulatory mechanism of Ca2+/calmodulin-dependent protein kinase kinaseQ30859364
A CaMK cascade activates CRE-mediated transcription in neurons of Caenorhabditis elegansQ31109440
Mechanism of activation of ERK2 by dual phosphorylationQ31443949
Kinetic basis for activation of CDK2/cyclin A by phosphorylationQ31456489
Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.Q33879347
Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domainQ34189079
Identification and characterization of novel components of a Ca2+/calmodulin-dependent protein kinase cascade in HeLa cellsQ34224901
Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent protein kinases type I, II, and IV.Q34378147
Numb antagonizes Notch signaling to specify sibling neuron cell fatesQ34392095
Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?Q35047964
A requirement of hydrophobic and basic amino acid residues for substrate recognition by Ca2+/calmodulin-dependent protein kinase Ia.Q35573702
Isolation and comparison of rat cDNAs encoding Ca2+/calmodulin-dependent protein kinase I isoformsQ36850884
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineageQ37275107
Ca(2+)/Calmodulin-dependent protein kinase cascade in Caenorhabditis elegans. Implication in transcriptional activationQ39749408
14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase.Q40464497
Regulation of cyclin D1/Cdk4 complexes by calcium/calmodulin-dependent protein kinase I.Q40593826
Characterization of Ca2+/calmodulin-dependent protein kinase I as a myosin II regulatory light chain kinase in vitro and in vivoQ42157499
Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I.Q44844953
Mechanism of the generation of autonomous activity of Ca2+/calmodulin-dependent protein kinase IV.Q44985658
CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinasesQ45137410
Immunochemical localization of calcium/calmodulin-dependent protein kinase I.Q47070053
Identification and characterization of two Ca2+/CaM-dependent protein kinases required for normal nuclear division in Aspergillus nidulans.Q47829200
Regulatory mechanism of Dictyostelium myosin light chain kinase A.Q48166039
Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.Q52088466
Characterization of a Ca2+/Calmodulin-dependent Protein Kinase CascadeQ56592961
A phosphotyrosine interaction domainQ56918691
P433issue42
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)35108-35118
P577publication date2005-08-16
P1433published inJournal of Biological ChemistryQ867727
P1476titlePhosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases
P478volume280

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Q24338740aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

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