| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0306-4522(99)00390-5 |
| P698 | PubMed publication ID | 10619481 |
| P2093 | author name string | Beck M | |
| Holzer M | |||
| Arendt T | |||
| Bigl V | |||
| Brückner MK | |||
| Pannicke T | |||
| Kaap S | |||
| P2860 | cites work | Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice | Q22242267 |
| Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein | Q22251280 | ||
| Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 | Q25938983 | ||
| Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction | Q25938986 | ||
| Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa | Q27861105 | ||
| Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene | Q28776291 | ||
| Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue | Q29615225 | ||
| The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor | Q29618322 | ||
| Genomic organization of the human amyloid beta-protein precursor gene | Q34151473 | ||
| Early prenatal ontogenesis of the cerebral cortex (neocortex) of the cat (Felis domestica). A Golgi study. I. The primordial neocortical organization | Q34223669 | ||
| Dual origin of the mammalian neocortex and evolution of the cortical plate | Q34257695 | ||
| Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay | Q48917972 | ||
| Growth and development of the brain and spinal cord of the guinea pig | Q48939994 | ||
| Differential splicing of Alzheimer's disease amyloid A4 precursor RNA in rat tissues: PreA4(695) mRNA is predominantly produced in rat and human brain | Q49100289 | ||
| APP gene family. Alternative splicing generates functionally related isoforms | Q49162225 | ||
| An alternative secretase cleavage produces soluble Alzheimer amyloid precursor protein containing a potentially amyloidogenic sequence | Q53179651 | ||
| Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain. | Q53187068 | ||
| Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. | Q53188216 | ||
| Scavenging of Alzheimer's amyloid beta-protein by microglia in culture. | Q53213552 | ||
| Electrophoretic Separation of βA4 Peptides (1–40) and (1–42) | Q58478308 | ||
| Expression of beta-amyloid precursor protein in reactive astrocytes following neuronal damage | Q69282065 | ||
| Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics | Q70257797 | ||
| Amyloid precursor protein metabolism in primary cell cultures of neurons, astrocytes, and microglia | Q71082198 | ||
| Trophic interactions between astroglial cells and hippocampal neurons in culture | Q71279969 | ||
| Neurons switch from non-neuronal enolase to neuron-specific enolase during differentiation | Q71503661 | ||
| The carboxyl termini of beta-amyloid peptides 1-40 and 1-42 are generated by distinct gamma-secretase activities | Q71763263 | ||
| Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. | Q34438409 | ||
| The PreA4(695) precursor protein of Alzheimer's disease A4 amyloid is encoded by 16 exons | Q35862214 | ||
| Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons | Q36110179 | ||
| Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells | Q36152115 | ||
| Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity | Q36415795 | ||
| Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease | Q36482688 | ||
| Aged Non-Human Primates: An Animal Model of Age-Associated Neurodegenerative Disease | Q36554296 | ||
| Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities | Q36689365 | ||
| Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology | Q36724967 | ||
| The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry | Q36835366 | ||
| Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage | Q37239146 | ||
| Glial fibrillary acidic protein (GFAP): the major protein of glial intermediate filaments in differentiated astrocytes | Q38148892 | ||
| Rat cortical neurons in cell culture: Culture methods, cell morphology, electrophysiology, and synapse formation | Q39199740 | ||
| Cellular and molecular biology of Alzheimer's disease and animal models | Q40759701 | ||
| Normal and abnormal biology of the beta-amyloid precursor protein | Q40766055 | ||
| A beta A4 amyloid precursor protein gene and Alzheimer's disease | Q40981910 | ||
| Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells | Q41121149 | ||
| Rapid cellular uptake of Alzheimer amyloid betaA4 peptide by cultured human neuroblastoma cells | Q41165905 | ||
| Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils | Q41173971 | ||
| Strategies to alter the progression of Alzheimer's disease | Q41238766 | ||
| Amyloid beta protein (A beta) removal by neuroglial cells in culture | Q41300362 | ||
| Amyloid, the presenilins and Alzheimer's disease | Q41433661 | ||
| Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive | Q41450284 | ||
| Production of the Alzheimer amyloid beta protein by normal proteolytic processing | Q41599298 | ||
| Amyloid beta-peptide is produced by cultured cells during normal metabolism | Q41602809 | ||
| Overexpression of amyloid precursor protein alters its normal processing and is associated with neurotoxicity | Q41643587 | ||
| Cleavage of amyloid beta peptide during constitutive processing of its precursor | Q41852594 | ||
| The mechanism of cytosine arabinoside toxicity on quiescent astrocytes in vitro appears to be analogous to in vivo brain injury | Q42202546 | ||
| DLX-2, MASH-1, and MAP-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain. | Q42493260 | ||
| Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture | Q42805272 | ||
| Expression of the three opioid receptor subtypes mu, delta and kappa in guinea pig and rat brain cell cultures and in vivo | Q44339963 | ||
| Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide | Q46160439 | ||
| Beta-amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease | Q46269300 | ||
| AMPA receptor subunits expressed by single Purkinje cells | Q46590834 | ||
| beta-Amyloid peptide produced in vitro is degraded by proteinases released by cultured cells | Q46631570 | ||
| The neurofilament triplet is present in distinct subpopulations of neurons in the central nervous system of the guinea-pig | Q46750168 | ||
| Amyloid precursor protein in guinea pigs--complete cDNA sequence and alternative splicing | Q48052458 | ||
| Complementary DNA for the mouse homolog of the human amyloid beta protein precursor | Q48170771 | ||
| Fibronectin-like immunoreactivity in the developing cerebral cortex | Q48197782 | ||
| Amyloidogenicity of rodent and human beta A4 sequences | Q48266969 | ||
| Human and rodent Alzheimer beta-amyloid peptides acquire distinct conformations in membrane-mimicking solvents | Q48346209 | ||
| Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus | Q48349302 | ||
| Neuron-specific enolase: complete structure of rat mRNA, multiple transcriptional start sites, and evidence suggesting post-transcriptional control | Q48398470 | ||
| Proteolytic degradation of Alzheimer's disease amyloid beta-peptide by a metalloproteinase from microglia cells. | Q48547076 | ||
| Alzheimer's disease beta-amyloid precursor protein in rat neural cells in culture | Q48581477 | ||
| The beta-amyloid epitope masking activity in human brain is identified as albumin | Q48603297 | ||
| Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal cultures | Q48625535 | ||
| Heterogeneity of astrocyte resting membrane potentials and intercellular coupling revealed by whole-cell and gramicidin-perforated patch recordings from cultured neocortical and hippocampal slice astrocytes. | Q48630186 | ||
| Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis | Q48704603 | ||
| Improved electrophoretic separation and immunoblotting of beta-amyloid (A beta) peptides 1-40, 1-42, and 1-43. | Q48772618 | ||
| Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence | Q48915342 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 243-254 | |
| P577 | publication date | 2000-01-01 | |
| P1433 | published in | Neuroscience | Q15708571 |
| P1476 | title | Guinea-pig primary cell cultures provide a model to study expression and amyloidogenic processing of endogenous amyloid precursor protein | |
| P478 | volume | 95 |
| Q36016766 | Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme |
| Q41924331 | Constitutive overactivation of protein kinase C in guinea pig brain increases alpha-secretory APP processing without decreasing beta-amyloid generation |
| Q43597738 | Developmentally induced microencephalopathy in guinea pigs--embryonic glial cell activation marks selective neuronal death |
| Q42810444 | Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs. |
| Q35098538 | Guinea pigs as a nontransgenic model for APP processing in vitro and in vivo |
| Q31078434 | Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. |
| Q34963305 | Large quantities of Abeta peptide are constitutively released during amyloid precursor protein metabolism in vivo and in vitro. |
| Q28070356 | On cognitive ecology and the environmental factors that promote Alzheimer disease: lessons from Octodon degus (Rodentia: Octodontidae) |
| Q39087660 | Population PKPD modeling of BACE1 inhibitor-induced reduction in Aβ levels in vivo and correlation to in vitro potency in primary cortical neurons from mouse and guinea pig. |
| Q37212020 | Revisiting rodent models: Octodon degus as Alzheimer's disease model? |
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