From in vitro EC₅₀ to in vivo dose-response for antiretrovirals using an HIV disease model. Part I: a framework

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From in vitro EC₅₀ to in vivo dose-response for antiretrovirals using an HIV disease model. Part I: a framework is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10928-012-9255-3
P698PubMed publication ID22736302

P2093author name stringJing Fang
Pravin R Jadhav
P2860cites workIsolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)Q22242256
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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cellsQ28369295
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Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugsQ37345610
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Intracellular Pharmacokinetics of Antiretroviral Drugs in HIV-Infected Patients, and their Correlation with Drug ActionQ37650120
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Tenofovir, adefovir, and zidovudine susceptibilities of primary human immunodeficiency virus type 1 isolates with non-B subtypes or nucleoside resistanceQ43719445
Antiviral dynamics and sex differences of zidovudine and lamivudine triphosphate concentrations in HIV-infected individualsQ44605402
Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delayQ44668486
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P433issue4
P921main subjectanti-retroviral agentQ50430310
P304page(s)357-368
P577publication date2012-06-27
P1433published inJournal of Pharmacokinetics and PharmacodynamicsQ15766045
P1476titleFrom in vitro EC₅₀ to in vivo dose-response for antiretrovirals using an HIV disease model. Part I: a framework
P478volume39

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cites work (P2860)
Q40677725Characterizing Class-Specific Exposure-Viral Load Suppression Response of HIV Antiretrovirals Using A Model-Based Meta-Analysis
Q47407899From in vitro EC₅₀ to in vivo dose-response for antiretrovirals using an HIV disease model. Part II: application to drug development
Q37656345Integrated population pharmacokinetic/viral dynamic modelling of lopinavir/ritonavir in HIV-1 treatment-naïve patients
Q42284705Model based design and analysis of phase II HIV-1 trials.