scholarly article | Q13442814 |
P50 | author | Jinjian Lu | Q42709768 |
P2093 | author name string | Xiuping Chen | |
Wenxue Li | |||
Jiajie Guo | |||
Guowen Ren | |||
Tongye Sha | |||
P2860 | cites work | LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing | Q24597817 |
Autophagy modulation as a potential therapeutic target for diverse diseases | Q27010076 | ||
The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer | Q28297155 | ||
Cucurbitacin B has a potent antiproliferative effect on breast cancer cells in vitro and in vivo | Q39961315 | ||
A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. | Q43798608 | ||
Assays to assess autophagy induction and fusion of autophagic vacuoles with a degradative compartment, using monodansylcadaverine (MDC) and DQ-BSA. | Q46129573 | ||
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells | Q46884660 | ||
Cucurbitacin B induces cell cycle arrest, apoptosis and autophagy associated with G actin reduction and persistent activation of cofilin in Jurkat cells. | Q52626467 | ||
Oxidative stress and autophagy: the clash between damage and metabolic needs | Q28387805 | ||
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling | Q28388989 | ||
Methods in mammalian autophagy research | Q29547276 | ||
The Beclin 1 network regulates autophagy and apoptosis | Q29616539 | ||
Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B. | Q33339967 | ||
Autophagy and cancer therapy | Q33584607 | ||
Cucurbitacin I induces protective autophagy in glioblastoma in vitro and in vivo | Q33675791 | ||
Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression | Q33688434 | ||
Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer | Q34112882 | ||
Biological activities and potential molecular targets of cucurbitacins: a focus on cancer | Q34273013 | ||
DNA damage-induced activation of ATM and ATM-dependent signaling pathways | Q34336538 | ||
Cucurbitacins and cucurbitane glycosides: structures and biological activities | Q34433152 | ||
Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation | Q34444520 | ||
Inhibitory effects of cucurbitacin B on laryngeal squamous cell carcinoma | Q34588898 | ||
ROS, mitochondria and the regulation of autophagy | Q34679713 | ||
Antiproliferative effects of cucurbitacin B in breast cancer cells: down-regulation of the c-Myc/hTERT/telomerase pathway and obstruction of the cell cycle | Q35002186 | ||
Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. | Q35063122 | ||
Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner | Q35088525 | ||
Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated β-catenin to the nucleus. | Q35631729 | ||
The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer | Q36763291 | ||
Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma | Q37047540 | ||
Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment | Q37283952 | ||
gammaH2AX: a sensitive molecular marker of DNA damage and repair | Q37687078 | ||
The DNA damage response and cancer therapy | Q37977004 | ||
γH2AX as a novel endpoint to detect DNA damage: applications for the assessment of the in vitro genotoxicity of cigarette smoke | Q38021898 | ||
DNA damage sensing by the ATM and ATR kinases. | Q38134064 | ||
Therapeutic targeting of autophagy in cancer. Part II: pharmacological modulation of treatment-induced autophagy | Q38220560 | ||
Cucurbitacin IIa induces caspase-3-dependent apoptosis and enhances autophagy in lipopolysaccharide-stimulated RAW 264.7 macrophages. | Q39173587 | ||
Cucurbitacin B potently suppresses non-small-cell lung cancer growth: identification of intracellular thiols as critical targets | Q39206697 | ||
Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis. | Q39375263 | ||
Cucurbitacin B induces rapid depletion of the G-actin pool through reactive oxygen species-dependent actin aggregation in melanoma cells. | Q39530449 | ||
Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin | Q39702599 | ||
Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration | Q39740110 | ||
Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells | Q39770785 | ||
Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells | Q39824976 | ||
P433 | issue | 4 | |
P921 | main subject | autophagy | Q288322 |
reactive oxygen species | Q424361 | ||
P304 | page(s) | 522-530 | |
P577 | publication date | 2015-05-28 | |
P1433 | published in | Journal of Natural Medicines | Q20182030 |
P1476 | title | Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells | |
P478 | volume | 69 |
Q36634632 | A triterpenoid from wild bitter gourd inhibits breast cancer cells |
Q38743353 | Carbazole alkaloids from Murraya koenigii trigger apoptosis and autophagic flux inhibition in human oral squamous cell carcinoma cells |
Q48301430 | Cucurbitacin B Protects Against Pressure Overload Induced Cardiac Hypertrophy. |
Q37701484 | Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways |
Q87742397 | Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells |
Q40506281 | Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana). |
Q38972954 | Inhibiting reactive oxygen species-dependent autophagy enhanced baicalein-induced apoptosis in oral squamous cell carcinoma |
Q39410995 | Natural Compounds from Herbs that can Potentially Execute as Autophagy Inducers for Cancer Therapy. |
Q39042339 | Natural products as modulator of autophagy with potential clinical prospects |
Q26753053 | New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy |
Q48105319 | Oridonin induces apoptosis in human oral cancer cells via phosphorylation of histone H2AX. |
Q37500854 | PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells. |
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