Protection from lethality and behavioral incapacitation resulting from intoxication by soman (pinacolyl methylphosphonofluoridate) and treatment with atropine sulfate and 2-PAM chloride in the guinea pig, cavia porcellus

scientific article

Protection from lethality and behavioral incapacitation resulting from intoxication by soman (pinacolyl methylphosphonofluoridate) and treatment with atropine sulfate and 2-PAM chloride in the guinea pig, cavia porcellus is …
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scholarly articleQ13442814

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P356DOI10.3109/01480549109017867
P698PubMed publication ID1889376

P50authorMary Z MaysQ59692086
P2093author name stringMays MZ
Murrow ML
Romano JA Jr
Terry MR
P2860cites workQuantitative studies of the effect of antagonists on the acute toxicity of organophosphates in ratsQ35225901
Comparing the response surfaces of two cholinolytics when used in combination with physostigmine as a pretreatment against organophosphate challengeQ41985124
Atropine sulfate and 2-pyridine aldoxime methylchloride elicit stress-induced convulsions and lethality in mice and guinea pigsQ42230236
Assessing the efficacy of azaprophen and physostigmine as a pretreatment for soman-induced incapacitation in guinea pigs by response-surface modelingQ44303871
The protection of animals against organophosphate poisoning by pretreatment with a carbamateQ46586307
Application of response surface methods for evaluating the interactions of soman, atropine, and pralidioxime chlorideQ46716290
Long-term behavioral changes in rats following organophosphonate exposureQ48959284
Time course effects of soman on acetylcholine and choline levels in six discrete areas of the rat brainQ49088662
Treatment of poisoning by soman.Q51818352
Neurobehavioral effects of repeated sublethal soman in primates.Q52264389
Assessing pyridostigmine efficacy by response surface modeling.Q53895611
P433issue1-2
P921main subjectatropineQ26272
intoxicationQ18621601
Guinea-pigQ79803
somanQ408044
P304page(s)21-44
P577publication date1991-01-01
P1433published inDrug and Chemical ToxicologyQ5308876
P1476titleProtection from lethality and behavioral incapacitation resulting from intoxication by soman (pinacolyl methylphosphonofluoridate) and treatment with atropine sulfate and 2-PAM chloride in the guinea pig, cavia porcellus
P478volume14

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cites work (P2860)
Q44454601Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose
Q52176537In vitro and in vivo comparison of sulfur donors as antidotes to acute cyanide intoxication.