Inhibition of plasminogen activator inhibitor-1 activity results in promotion of endogenous thrombolysis and inhibition of thrombus extension in models of experimental thrombosis

scientific article published on January 1, 1992

Inhibition of plasminogen activator inhibitor-1 activity results in promotion of endogenous thrombolysis and inhibition of thrombus extension in models of experimental thrombosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/01.CIR.85.1.305
P953full work available at URLhttps://www.ahajournals.org/doi/pdf/10.1161/01.CIR.85.1.305
P698PubMed publication ID1728462

P2093author name stringH. Pannekoek
M. Levi
ten Cate JW
van Zonneveld AJ
J. W. ten Cate
B. J. Biemond
A. J. van Zonneveld
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectblood coagulationQ179217
Cardiology and cardiovascular medicineQ96320350
plasminogenQ107129060
thrombosisQ261327
thrombolysisQ1931577
P304page(s)305-312
P577publication date1992-01-01
P1433published inCirculationQ578091
P1476titleInhibition of plasminogen activator inhibitor-1 activity results in promotion of endogenous thrombolysis and inhibition of thrombus extension in models of experimental thrombosis
P478volume85

Reverse relations

cites work (P2860)
Q43151596Activation of single-chain urokinase-type plasminogen activator by platelet-associated plasminogen: a mechanism for stimulation of fibrinolysis by platelets.
Q35747706Aging accelerates endotoxin-induced thrombosis : increased responses of plasminogen activator inhibitor-1 and lipopolysaccharide signaling with aging
Q24310458Anticoagulant and antithrombotic properties of platelet protease nexin-1
Q43185376Antithrombotic activity of a monoclonal antibody inducing the substrate form of plasminogen activator inhibitor type 1 in rat models of venous and arterial thrombosis
Q73940083Association of hemostatic factors with peripheral vascular disease
Q35833573Atheromatous plaque macrophages produce plasminogen activator inhibitor type-1 and stimulate its production by endothelial cells and vascular smooth muscle cells
Q47772414Beyond fibrinolysis: the role of plasminogen activator inhibitor-1 and vitronectin in vascular wound healing.
Q27675149Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 That Accelerates the Transition into the Latent Conformation
Q73360690Cloning of a single-chain variable fragment (scFv) switching active plasminogen activator inhibitor-1 to substrate
Q33502675Current drug treatment strategies for disseminated intravascular coagulation
Q33371584Effect of Reteplase and PAI-1 antibodies on postoperative adhesion formation in a laparoscopic mouse model
Q43117440Effect of the small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor, PAI-749, in clinical models of fibrinolysis
Q44518810Elucidation of a novel epitope of a substrate-inducing monoclonal antibody against the serpin PAI-1.
Q90142206Engineered microparticles and nanoparticles for fibrinolysis
Q73705922Epitopes on plasminogen activator inhibitor type-1 important for binding to tissue plasminogen activator
Q51068066Eplerenone reduces arterial thrombosis in diabetic rats.
Q33504864Fibrinogen-coated albumin microcapsules reduce bleeding in severely thrombocytopenic rabbits
Q40582633Fibrinolysis and thrombosis
Q73886817Identification of functional synergism between monoclonal antibodies. Application to the enhancement of plasminogen activator inhibitor-1 neutralizing effects
Q34006140Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence
Q58863655In vivo veritas: Thrombosis mechanisms in animal models
Q35764729Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha
Q71901188Inhibition of plasminogen activator inhibitor-1 activity by two diketopiperazines, XR330 and XR334 produced by Streptomyces sp
Q40452547Is Familial Mediterranean Fever a thrombotic disease or not?
Q33700633Leptin upregulates the expression of plasminogen activator inhibitor-1 in human vascular endothelial cells
Q41735648Modulation of plasminogen activator inhibitor type-1 biosynthesis in vitro and in vivo with oligo(nucleoside phosphorothioate)s and related constructs
Q47793711Myocardial infarction occurs with a similar 24 h pattern in the 4G/5G versions of plasminogen activator inhibitor-1.
Q73107303Neutralization of plasminogen activator inhibitor-1 inhibitory properties: identification of two different mechanisms
Q44088573Novel inhibitors of plasminogen activator inhibitor-1: development of new templates from diketopiperazines
Q33337844Osteonecrosis induced by a single administration of low-dose lipopolysaccharide in rabbits
Q34220031Peptide-mediated inactivation of recombinant and platelet plasminogen activator inhibitor-1 in vitro
Q36039212Pivotal role of plasminogen-activator inhibitor 1 in vascular disease
Q33790622Plasma fibrinolysis inhibitor levels in acute stroke patients with thrombolysis failure
Q33832519Plasma plasminogen activator inhibitor 1, insulin resistance and android obesity
Q73295877Plasminogen Activator Inhibitor 1: Molecular Aspects and Clinical Importance
Q35688843Plasminogen activator inhibitor 1 (PAI-1): in vitro activities and clinical relevance
Q34384932Plasminogen activator inhibitor type-1 (part two): role for failure of thrombolytic therapy. PAI-1 resistance as a potential benefit for new fibrinolytic agents
Q40305997Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis
Q35450594Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow
Q33845781Platelet protease nexin-1, a serpin that strongly influences fibrinolysis and thrombolysis
Q33984228Pleiotropic functions of plasminogen activator inhibitor-1.
Q73295825Potential Antithrombotic and Fibrinolytic Properties of the Angiotensin Converting Enzyme Inhibitors
Q77295577Pretreatment plasminogen activator inhibitor-1 (PAI-1) levels and the outcome of thrombolysis with streptokinase in patients with acute myocardial infarction
Q73999113Prognostic role of plasminogen-activator-inhibitor-1 levels in treatment with streptokinase of patients with acute myocardial infarction
Q54628759Purification and characterization of active and stable recombinant plasminogen-activator inhibitor accumulated at high levels in Escherichia coli.
Q33950656Relationship between plasma plasminogen activator inhibitor 1 and insulin resistance
Q28272554Role of vitronectin and its receptors in haemostasis and vascular remodeling
Q32037411Selection of peptides that bind to plasminogen activator inhibitor 1 (PAI-1) using random peptide phage-display libraries
Q36456292Surface modification of PVDF using non-mammalian sources of collagen for enhancement of endothelial cell functionality.
Q58106436Systemic inhibition and liver-specific over-expression of PAI-1 failed to improve survival in all-inclusive populations or homogenous cohorts of CLP mice
Q73579431T-686, a novel inhibitor of plasminogen activator inhibitor-1, inhibits thrombosis without impairment of hemostasis in rats
Q83306169The effect of high plasma levels of angiotensin-converting enzyme (ACE) and plasminogen activator inhibitor (PAI-1) on the reperfusion after thrombolytic therapy in patients presented with acute myocardial infarction
Q43264477The interaction between components of the fibrinolytic system and GPIb/V/IX of platelets thrombus formation in mice
Q45842157The role of thrombin activatable fibrinolysis inhibitor and factor XI in platelet-mediated fibrinolysis resistance: a thromboelastographic study in whole blood
Q40894566The status of plasminogen activator inhibitor-1 as a therapeutic target
Q35684759Therapeutic value of small molecule inhibitor to plasminogen activator inhibitor-1 for lung fibrosis
Q49558417Thrombin Provokes Degranulation of Platelet α-Granules Leading to the Release of Active Plasminogen Activator Inhibitor-1 (PAI-1).
Q36868343VEGF levels in plasma in relation to platelet activation, glycemic control, and microvascular complications in type 1 diabetes.
Q37802497Venous Thromboembolic Disease and Hematologic Considerations in Obesity
Q73130642YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice
Q41228470α(1,3)-Fucosyltransferases FUT4 and FUT7 control murine susceptibility to thrombosis

Search more.