DNA based vaccination with a cocktail of plasmids encoding immunodominant Leishmania (Leishmania) major antigens confers full protection in BALB/c mice

scientific article published on 23 October 2008

DNA based vaccination with a cocktail of plasmids encoding immunodominant Leishmania (Leishmania) major antigens confers full protection in BALB/c mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VACCINE.2008.10.013
P698PubMed publication ID18951941

P50authorYassine ChtourouQ42747577
Koussay DellagiQ95146463
P2093author name stringSami Ben Hadj Ahmed
Chokri Bahloul
Leila Touihri
P2860cites workDNA vaccines: immunology, application, and optimization*Q28145651
Leishmania/HIV co-infections: epidemiology in Europe.Q30336421
Cross-protective efficacy of a prophylactic Leishmania donovani DNA vaccine against visceral and cutaneous murine leishmaniasisQ33796005
Leishmaniasis: current status of vaccine developmentQ33941719
Protection against cutaneous leishmaniasis induced by recombinant antigens in murine and nonhuman primate models of the human diseaseQ34008104
Leishmania donovani p36(LACK) DNA vaccine is highly immunogenic but not protective against experimental visceral leishmaniasisQ34008441
Heterogeneity of wild Leishmania major isolates in experimental murine pathogenicity and specific immune responseQ34008582
Vaccination with plasmid DNA encoding TSA/LmSTI1 leishmanial fusion proteins confers protection against Leishmania major infection in susceptible BALB/c miceQ34123352
Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasisQ34128082
Type 1 and type 2 responses to Leishmania majorQ34635606
Evasion of innate immunity by parasitic protozoaQ34983845
Culture microtitration: a sensitive method for quantifying Leishmania infantum in tissues of infected miceQ35118989
HIV and the transmission of LeishmaniaQ35609024
DNA immunization with the gene encoding P4 nuclease of Leishmania amazonensis protects mice against cutaneous LeishmaniasisQ36376098
The Leishmania infantum acidic ribosomal protein P0 administered as a DNA vaccine confers protective immunity to Leishmania major infection in BALB/c miceQ36376320
Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania majorQ36380692
The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challengeQ37227569
Evaluation of the murine immune response to Leishmania meta 1 antigen delivered as recombinant protein or DNA vaccine.Q40694366
Multiple pathways for the initiation of T helper 2 (Th2) responsesQ42947603
Vaccination with plasmid DNA encoding KMPII, TRYP, LACK and GP63 does not protect dogs against Leishmania infantum experimental challengeQ43223330
A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania majorQ43604612
A heterologous prime-boost regime using DNA and recombinant vaccinia virus expressing the Leishmania infantum P36/LACK antigen protects BALB/c mice from cutaneous leishmaniasis.Q43861566
Protective efficacy of a tandemly linked, multi-subunit recombinant leishmanial vaccine (Leish-111f) formulated in MPL adjuvantQ44126498
Genetic vaccination against leishmaniasisQ45026373
Genetic immunization with glycoprotein 63 cDNA results in a helper T cell type 1 immune response and protection in a murine model of leishmaniasisQ45889225
Comparison of potential protection induced by three vaccination strategies (DNA/DNA, Protein/Protein and DNA/Protein) against Leishmania major infection using Signal Peptidase type I in BALB/c miceQ46946752
A comparative evaluation of different DNA vaccine candidates against experimental murine leishmaniasis due to L. majorQ47805253
Optimization of DNA vaccination against cutaneous leishmaniasis.Q52009810
The potency and durability of DNA- and protein-based vaccines against Leishmania major evaluated using low-dose, intradermal challenge.Q52020458
Immunogenicity of a multicomponent DNA vaccine against visceral leishmaniasis in dogs.Q53609100
Therapy of murine cutaneous leishmaniasis by DNA vaccination.Q54050407
Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovaniQ56749822
Intramuscular immunization with p36(LACK) DNA vaccine induces IFN-γ production but does not protect BALB/c mice against Leishmania chagasi intravenous challengeQ58824983
Vaccination with a plasmid DNA cocktail encoding the nucleosomal histones of Leishmania confers protection against murine cutaneous leishmaniosisQ63408514
Requirements for the maintenance of Th1 immunity in vivo following DNA vaccination: a potential immunoregulatory role for CD8+ T cellsQ73948770
Vaccination with recombinant Parasite Surface Antigen 2 from Leishmania major induces a Th1 type of immune response but does not protect against infectionQ77489424
Vaccine requirements for sustained cellular immunity to an intracellular parasitic infectionQ77658710
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)99-106
P577publication date2008-10-23
P1433published inVaccineQ7907941
P1476titleDNA based vaccination with a cocktail of plasmids encoding immunodominant Leishmania (Leishmania) major antigens confers full protection in BALB/c mice
P478volume27

Reverse relations

cites work (P2860)
Q35517074An overview on Leishmania vaccines: A narrative review article
Q33633286BALB/c mice vaccinated with Leishmania major ribosomal proteins extracts combined with CpG oligodeoxynucleotides become resistant to disease caused by a secondary parasite challenge
Q39278829Cloning of a Recombinant Plasmid Encoding Thiol-Specific Antioxidant Antigen (TSA) Gene of Leishmania majorand Expression in the Chinese Hamster Ovary Cell Line.
Q30578697Combined immunization using DNA-Sm14 and DNA-Hsp65 increases CD8+ memory T cells, reduces chronic pathology and decreases egg viability during Schistosoma mansoni infection
Q40105761Comparative Assessment of Induced Immune Responses Following Intramuscular Immunization with Fusion and Cocktail of LeIF, LACK and TSA Genes Against Cutaneous Leishmaniasis in BALB/c Mice
Q38081358DNA immunization as an efficient strategy for vaccination
Q37682900DNA vaccines: a rational design against parasitic diseases.
Q35688323Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs
Q33732102Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins
Q41404819Head-to-head comparison of three vaccination strategies based on DNA and raw insect-derived recombinant proteins against Leishmania.
Q37053209Immune responses in DNA vaccine formulated with PMMA following immunization and after challenge with Leishmania major
Q90055472Immunization against Leishmania major infection in BALB/c mice using a subunit-based DNA vaccine derived from TSA, LmSTI1, KMP11, and LACK predominant antigens
Q37773297Immunotherapy as a strategy for treatment of leishmaniasis: a review of the literature.
Q52659333Induction of Immune Responses by DNA Vaccines Formulated with Dendrimer and Poly (Methyl Methacrylate) (PMMA) Nano-Adjuvants in BALB/c Mice Infected with Leishmania major.
Q39284066The immune response induced by DNA vaccine expressing nfa1 gene against Naegleria fowleri.
Q34724869Vaccination with lentiviral vector expressing the nfa1 gene confers a protective immune response to mice infected with Naegleria fowleri

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