Susceptibility of amyloid beta peptide degrading enzymes to oxidative damage: a potential Alzheimer's disease spiral

scientific article

Susceptibility of amyloid beta peptide degrading enzymes to oxidative damage: a potential Alzheimer's disease spiral is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BI050650L
P698PubMed publication ID16285738

P2093author name stringLouis B Hersh
Eun Suk Song
Heather Shinall
P433issue46
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
P304page(s)15345-15350
P577publication date2005-11-01
P1433published inBiochemistryQ764876
P1476titleSusceptibility of amyloid beta peptide degrading enzymes to oxidative damage: a potential Alzheimer's disease spiral
P478volume44

Reverse relations

cites work (P2860)
Q34225229Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease
Q28477836Alzheimer's disease and non-demented high pathology control nonagenarians: comparing and contrasting the biochemistry of cognitively successful aging
Q35917682BACE2 expression increases in human neurodegenerative disease
Q36659692Biomarkers for oxidative stress status of DNA, lipids, and proteins in vitro and in vivo cancer research
Q26771852Cerebrovascular disease in ageing and Alzheimer's disease
Q34665155Decreased Neprilysin and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease
Q27022552Diabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stress
Q39987132Down-regulation of insulin-degrading enzyme by presenilin 1 V97L mutant potentially underlies increased levels of amyloid beta 42.
Q33642530Effects of 4-hydroxy-nonenal and Amyloid-beta on expression and activity of endothelin converting enzyme and insulin degrading enzyme in SH-SY5Y cells
Q37219722Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells
Q46208530Experimental investigation of antibody-mediated clearance mechanisms of amyloid-beta in CNS of Tg-SwDI transgenic mice.
Q37319051Getting the iron out: phlebotomy for Alzheimer's disease?
Q42130528HIV-1 reduces Abeta-degrading enzymatic activities in primary human mononuclear phagocytes
Q36660696In vitro oxidative inactivation of human presequence protease (hPreP).
Q35500677Loss of neutral endopeptidase activity contributes to neutrophil activation and cardiac dysfunction during chronic hypomagnesemia: Protection by substance P receptor blockade
Q35687287Mechanisms of brain aging regulation by insulin: implications for neurodegeneration in late-onset Alzheimer's disease
Q38910551Mercury Reduces the Enzymatic Activity of Neprilysin in Differentiated SH-SY5Y Cells
Q33646882Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology
Q27652766Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme †
Q24657471Molecular basis for the thiol sensitivity of insulin-degrading enzyme
Q50932512Multiple functions of insulin-degrading enzyme: a metabolic crosslight?
Q34581928N-acetylcysteine prevents 4-hydroxynonenal- and amyloid-beta-induced modification and inactivation of neprilysin in SH-SY5Y cells
Q37408544Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's Disease
Q37150753Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia
Q26828757On the role of 4-hydroxynonenal in health and disease
Q92384162Oxidative inactivation of amyloid beta-degrading proteases by cholesterol-enhanced mitochondrial stress
Q38016899Proteolytic degradation of amyloid β-protein
Q34672360Proteolytically inactive insulin-degrading enzyme inhibits amyloid formation yielding non-neurotoxic aβ peptide aggregates
Q42366918Proteomic Characterization of Armillaria mellea Reveals Oxidative Stress Response Mechanisms and Altered Secondary Metabolism Profiles
Q34712680Redox regulation of insulin degradation by insulin-degrading enzyme
Q58842294Role of amyloid-β–metal interactions in Alzheimer’s disease
Q24317274Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE
Q40782441Structure, function, and regulation of insulin-degrading enzyme
Q92008457Supraphysiologic-dose anabolic-androgenic steroid use: A risk factor for dementia?
Q38664408Targeting Insulin-Degrading Enzyme to Treat Type 2 Diabetes Mellitus
Q48459186Tat peptides inhibit neprilysin
Q50059412The antioxidant xanthorrhizol prevents amyloid-β-induced oxidative modification and inactivation of neprilysin
Q28574836The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesis
Q34657827The irreversible binding of amyloid peptide substrates to insulin-degrading enzyme: a biological perspective
Q35908404The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.
Q36812453Transcriptional regulation of insulin-degrading enzyme modulates mitochondrial amyloid β (Aβ) peptide catabolism and functionality.
Q41674220White matter hypoperfusion and damage in dementia: post-mortem assessment
Q21284467beta-Amyloid degradation and Alzheimer's disease