CYP725A4 from yew catalyzes complex structural rearrangement of taxa-4(5),11(12)-diene into the cyclic ether 5(12)-oxa-3(11)-cyclotaxane. (scientific article published on 31 December 2007)

Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5alpha-ol: the first oxygenation step in taxol biosynthesis

Q28289878

Taxol production and taxadiene synthase activity in Taxus canadensis cell suspension cultures

Q28302655

Suppression of a P450 hydroxylase gene in plant trichome glands enhances natural-product-based aphid resistance.

Q30662365

Taxol biosynthetic genes

Q31004828

Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis

Q31072227

Cytochrome p450 taxadiene 5alpha-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis

Q33202568

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

Q33951756

Taxol: biosynthesis, molecular genetics, and biotechnological applications

Q34427992

The use of deuterium isotope effects to probe the active site properties, mechanism of cytochrome P450-catalyzed reactions, and mechanisms of metabolically dependent toxicity

Q35587724

Metabolism of capsaicinoids by P450 enzymes: a review of recent findings on reaction mechanisms, bio-activation, and detoxification processes

Q36665729

Complex reactions catalyzed by cytochrome P450 enzymes

Q36713653

A cDNA clone for taxadiene synthase, the diterpene cyclase that catalyzes the committed step of taxol biosynthesis

Q36798017

Cloning, yeast expression, and characterization of the coupling of two distantly related Arabidopsis thaliana NADPH-cytochrome P450 reductases with P450 CYP73A5.

Q36872775

The taxol supply crisis. New NCI policies for handling the large-scale production of novel natural product anticancer and anti-HIV agents

Q40619566

Taxanes from rooted cuttings of Taxus canadensis

Q44499748

Development of a method to assess cigarette smoke intake

Q44740232

The taxane diterpenoids

Q44865401

Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of Taxol

Q45078830

Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae

Q46701927

Isolation and characterization of the CYP71D16 trichome-specific promoter from Nicotiana tabacum L.

Q48288002

Redirection of carotenoid metabolism for the efficient production of taxadiene [taxa-4(5),11(12)-diene] in transgenic tomato fruit.

Q50792614

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

Q53340989

Study on the cytochrome P450-mediated oxidative metabolism of the terpene alcohol linalool: Indication of biological epoxidation

Q56986890

P433

issue

P407

language of work or name

English

Q1860

P304

page(s)

6067-6075

P577

publication date

2007-12-31

P1433

published in

Journal of Biological Chemistry

Q867727

P1476

title

CYP725A4 from yew catalyzes complex structural rearrangement of taxa-4(5),11(12)-diene into the cyclic ether 5(12)-oxa-3(11)-cyclotaxane

P478

volume

283

Reverse relations

cites work (P2860)

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