Optimizing the binding of fullerene inhibitors of the HIV-1 protease through predicted increases in hydrophobic desolvation

scientific article

Optimizing the binding of fullerene inhibitors of the HIV-1 protease through predicted increases in hydrophobic desolvation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/JM970689R
P698PubMed publication ID9632374

P2093author name stringKenyon GL
Rubin Y
Friedman SH
Ganapathi PS
P433issue13
P407language of work or nameEnglishQ1860
P921main subjecthydrophobicityQ41854968
fullereneQ178026
P304page(s)2424-2429
P577publication date1998-06-01
P1433published inJournal of Medicinal ChemistryQ900316
P1476titleOptimizing the binding of fullerene inhibitors of the HIV-1 protease through predicted increases in hydrophobic desolvation
P478volume41

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cites work (P2860)
Q445937151,2,5,6-Tetra- O -benzyl- d -mannitol derivatives as novel HIV protease inhibitors
Q30940107A Parallel Library of all Seven A(2)+B(2)+C(2) T(h) Regioisomeric Hexakisadducts of Fullerene C(60): Inspiration from Werner's Octahedral Stereoisomerism This work was supported by a National Science Foundation Young Investigator Award (CHE-9457693)
Q73890671A convenient method for the computer-aided molecular design of carborane containing compounds
Q64017850An efficient approach to chiral fullerene derivatives by catalytic enantioselective 1,3-dipolar cycloadditions
Q85037178Binding of novel fullerene inhibitors to HIV-1 protease: insight through molecular dynamics and molecular mechanics Poisson-Boltzmann surface area calculations
Q36428981Binding of single walled carbon nanotube to WT and mutant HIV-1 proteases: analysis of flap dynamics and binding mechanism
Q58478921Biomedical Effects and Nanosafety of Engineered Nanomaterials: Recent Progress
Q38068131Chemical biology based on target-selective degradation of proteins and carbohydrates using light-activatable organic molecules
Q39324111Chemical methods for degradation of target proteins using designed light-activatable organic molecules.
Q40817228Computational studies of the binding mechanisms of fullerenes to human serum albumin
Q79822315Computational study of enantioselective interaction between C60 fullerene and its derivatives with L-histidine
Q55070276Deformation density components analysis of fullerene-based anti-HIV drugs.
Q44022775Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors
Q56979810Design, synthesis and biological properties of fulleropyrrolidine derivatives as potential DNA photo-probes
Q37843987From conventional to unusual enzyme inhibitor scaffolds: the quest for target specificity
Q37287731Fullerene Derivatives Strongly Inhibit HIV-1 Replication by Affecting Virus Maturation without Impairing Protease Activity
Q57810324Fullerene Derivatives of Nucleoside HIV Reverse Transcriptase Inhibitors-In Silico Activity Prediction
Q38200083Fullerene sugar balls: a new class of biologically active fullerene derivatives
Q34251777Fullerene-based amino acids and peptides.
Q40976731Fullerene-based inhibitors of HIV-1 protease
Q51176039Fullerol in human lens and retinal pigment epithelial cells: time domain fluorescence spectroscopy and imaging.
Q73203782Inhibition of E. coli growth by fullerene derivatives and inhibition mechanism
Q39805654Low-toxic and safe nanomaterials by surface-chemical design, carbon nanotubes, fullerenes, metallofullerenes, and graphenes.
Q40072219Molecular dynamics exploration of the binding mechanism and properties of single-walled carbon nanotube to WT and mutant VP35 FBP region of Ebola virus
Q42280379Receptor- and ligand-based study of fullerene analogues: comprehensive computational approach including quantum-chemical, QSAR and molecular docking simulations
Q44356920Respiratory chain inhibition by fullerene derivatives: hydrogen peroxide production caused by fullerene derivatives and a respiratory chain system
Q38393674Retroviral proteases and their roles in virion maturation
Q41031126Structural insight into the binding of C60-derivatives with enoyl-pyruvate transferase from Helicobacter pylori
Q58652119Suppression of Proinflammatory Cytokines in Functionalized Fullerene-Exposed Dermal Keratinocytes
Q93184868Synthesis and antitumor activity of novel pyridinium fullerene derivatives
Q64017915Synthesis of water soluble fulleropyrrolidines bearing biologically active arylpiperazines
Q39387906Target-selective photodegradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by designed fullerene-sugar hybrids
Q28543795Understanding the mechanism of atovaquone drug resistance in Plasmodium falciparum cytochrome b mutation Y268S using computational methods
Q27627507X-ray crystal structure of an anti-Buckminsterfullerene antibody Fab fragment: Biomolecular recognition of C60
Q33715235[Gd@C(82)(OH)(22)](n) nanoparticles induce dendritic cell maturation and activate Th1 immune responses

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