Prospective, open-label comparative study of liver toxicity in an unselected population of HIV-infected patients treated for the first time with efavirenz or nevirapine

scientific article published in November 2005

Prospective, open-label comparative study of liver toxicity in an unselected population of HIV-infected patients treated for the first time with efavirenz or nevirapine is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1310/EWWC-YLJ6-8LHE-054A
P8608Fatcat IDrelease_m7uzeazywfdqhd3hka3feej2l4
P698PubMed publication ID16452064

P2093author name stringLeonardo Calza
Roberto Manfredi
Francesco Chiodo
P2860cites workAn extremely different dysmetabolic profile between the two available nonnucleoside reverse transcriptase inhibitors: efavirenz and nevirapineQ45239039
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First-line efavirenz versus lopinavir-ritonavir-based highly active antiretroviral therapy for naive patientsQ46248542
Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel.Q50145200
Efavirenz versus nevirapine in current clinical practice: a prospective, open-label observational studyQ34546335
Interactions between recreational drugs and antiretroviral agentsQ34874414
HIV disease and advanced age: an increasing therapeutic challengeQ34967154
Non-nucleoside reverse transcriptase inhibitors--an overviewQ35093731
Human immunodeficiency virus and hepatitis C virus coinfection: epidemiology, natural history, therapeutic options and clinical managementQ35685244
Nevirapine in the treatment of HIV.Q35917412
The steady-state pharmacokinetics of nevirapine during once daily and twice daily dosing in HIV-1-infected individualsQ42627921
Gabexate mesilate and/or octreotide in human immunodeficiency virus-associated pancreatic abnormalitiesQ42683244
Safety and tolerance of efavirenz in different antiretroviral regimens: results from a national multicenter prospective study in 1,033 HIV-infected patientsQ43461248
Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infectionsQ43851688
A prospective comparison of the two main indications of efavirenz in 2001 highly active antiretroviral therapy (HAART) regimens: first-line versus salvage use.Q43988702
Normalization of liver enzymes in an HIV-hepatitis C virus-co-infected patient after potent antiretroviral therapyQ43988881
Incidence of and risk factors for severe hepatotoxicity associated with antiretroviral combination therapyQ44044990
Hepatotoxicity following nevirapine-containing regimens in HIV-1-infected individualsQ44131292
Mortality due to chronic viral liver disease among patients infected with human immunodeficiency virus.Q44169170
Short communication: interactions between nevirapine plasma levels, chronic hepatitis C, and the development of liver toxicity in HIV-infected patientsQ44399527
Incidence of liver toxicity in hiv-infected patients receiving isolated dual nucleoside analogue antitretroviral therapyQ44517773
Risk and determinants of developing severe liver toxicity during therapy with nevirapine-and efavirenz-containing regimens in HIV-infected patientsQ44660478
Serious adverse cutaneous and hepatic toxicities associated with nevirapine use by non-HIV-infected individualsQ44727378
Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN StudyQ44849439
No relationship between high nevirapine plasma concentration and hepatotoxicity in HIV-1-infected patients naive of antiretroviral treatment or switched from protease inhibitorsQ44905262
The relationship between nevirapine plasma concentrations and abnormal liver function testsQ45016090
P433issue6
P921main subjectefavirenzQ422645
P304page(s)302-311
P577publication date2005-11-01
P1433published inHIV Clinical TrialsQ15756361
P1476titleProspective, open-label comparative study of liver toxicity in an unselected population of HIV-infected patients treated for the first time with efavirenz or nevirapine
P478volume6

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cites work (P2860)
Q39530519Analysis of severe hepatic events associated with nevirapine-containing regimens: CD4+ T-cell count and gender in hepatitis C seropositive and seronegative patients
Q57180639Drug-drug interactions and clinical considerations with co-administration of antiretrovirals and psychotropic drugs
Q37139458EFV/FTC/TDF-associated hepatotoxicity: a case report and review
Q41392118Early changes in hepatic function among HIV-tuberculosis patients treated with nevirapine or efavirenz along with rifampin-based anti-tuberculosis therapy
Q30240127Efavirenz or nevirapine in three-drug combination therapy with two nucleoside or nucleotide-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals
Q24235724Efavirenz or nevirapine in three-drug combination therapy with two nucleoside-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals
Q36787311Efavirenz: a review
Q33795242Expenditures for the care of HIV-infected patients in rural areas in China's antiretroviral therapy programs.
Q36984240Idiosyncratic drug-induced liver injury: an overview
Q48254303Pooled week 96 results of the phase III DUET-1 and DUET-2 trials of etravirine: further analysis of adverse events and laboratory abnormalities of special interest

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