Machine-learning approach identifies a pattern of gene expression in peripheral blood that can accurately detect ischaemic stroke.

scientific article published on 30 November 2016

Machine-learning approach identifies a pattern of gene expression in peripheral blood that can accurately detect ischaemic stroke. is …
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scholarly articleQ13442814

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P356DOI10.1038/NPJGENMED.2016.38
P932PMC publication ID5685316
P698PubMed publication ID29263821

P50authorGrant C O'ConnellQ55444985
P2093author name stringTaura L Barr
Paul D Chantler
Ashley B Petrone
Noelle Lucke-Wold
Connie S Tennant
Madison B Treadway
P2860cites workHeart Disease and Stroke Statistics--2013 Update: A Report From the American Heart AssociationQ22306356
Acute Ischemic Cerebrovascular Syndrome: Diagnostic CriteriaQ22306376
Interaction of soluble CD163 with activated T lymphocytes involves its association with non-muscle myosin heavy chain type AQ24306764
Newly identified stress-responsive protein kinases, Krs-1 and Krs-2Q24308319
The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signalingQ24312928
CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobinQ28192232
Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signalingQ28202549
The immunology of stroke: from mechanisms to translationQ29620066
Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke AssociationQ29620546
Gene selection for sample classification based on gene expression data: study of sensitivity to choice of parameters of the GA/KNN methodQ30667225
Gene assessment and sample classification for gene expression data using a genetic algorithm/k-nearest neighbor method.Q30679676
Toward predicting metastatic progression of melanoma based on gene expression dataQ30924798
Identification of the haemoglobin scavenger receptor.Q33934404
Cause-specific mortality after first cerebral infarction: a population-based study.Q51663871
Using peripheral blood mononuclear cells to determine a gene expression profile of acute ischemic stroke: a pilot investigation.Q51980997
A solution to the problem of separation in logistic regression.Q52942642
Analysis of lymphocyte subsets in patients with stroke and their influence on infection after stroke.Q54720065
Requirement of protein kinase (Krs/MST) activation for MT-21-induced apoptosisQ73023828
Early stroke treatment associated with better outcome: the NINDS rt-PA stroke studyQ73288997
North Carolina stroke prevention and treatment facilities survey. Statewide availability of programs and servicesQ73334520
Diagnostic accuracy of stroke referrals from primary care, emergency room physicians, and ambulance staff using the face arm speech testQ78745291
NORMA-Gene: a simple and robust method for qPCR normalization based on target gene dataQ33938564
Soluble CD163 inhibits phorbol ester-induced lymphocyte proliferationQ34099986
Genomic biomarkers and cellular pathways of ischemic stroke by RNA gene expression profilingQ34140261
Only the soluble form of the scavenger receptor CD163 acts inhibitory on phorbol ester-activated T-lymphocytes, whereas membrane-bound protein has no effectQ34147333
Gene expression profiling of blood for the prediction of ischemic strokeQ34330510
Diagnostic potential of the NMDA receptor peptide assay for acute ischemic stroke.Q34359734
Blood biomarkers of ischemic strokeQ35648087
Association between stroke center hospitalization for acute ischemic stroke and mortalityQ35791828
Central nervous system injury-induced immune deficiency syndromeQ36257627
Brain-immune interactions and ischemic stroke: clinical implicationsQ36651081
Blood biomarkers in the diagnosis of ischemic stroke: a systematic reviewQ37227913
Anthrax toxin receptor 2 promotes human uterine smooth muscle cell viability, migration and contractilityQ37634195
Stroke biomarkers: progress and challenges for diagnosis, prognosis, differentiation, and treatmentQ37635613
Immunological consequences of ischemic stroke: immunosuppression and autoimmunity.Q37802525
Evolving role of biomarkers in acute cerebrovascular diseaseQ37997374
Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart AssociationQ38071269
Ischemic stroke biomarkers in bloodQ38079618
Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray studyQ38317059
Regulation of Rho signaling pathways in interleukin-2-stimulated human T-lymphocytes.Q38321326
KIF1B promotes glioma migration and invasion via cell surface localization of MT1-MMP.Q38818997
Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasionQ39203854
MAL protein controls protein sorting at the supramolecular activation cluster of human T lymphocytes.Q39555508
Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trialsQ39933423
Comparison of stroke recognition and stroke severity scores for stroke detection in a single cohortQ41736285
Serum free hemoglobin as a novel potential biomarker for acute ischemic strokeQ45406417
Emergency department arrival times after acute ischemic stroke during the 1990sQ48109863
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectmachine learningQ2539
P304page(s)16038
P577publication date2016-11-30
P1433published inNPJ genomic medicineQ27727516
P1476titleMachine-learning approach identifies a pattern of gene expression in peripheral blood that can accurately detect ischaemic stroke
P478volume1