Discovering the potential of S. clavuligerus for bioactive compound production: cross-talk between the chromosome and the pSCL4 megaplasmid

scientific article published on 25 November 2017

Discovering the potential of S. clavuligerus for bioactive compound production: cross-talk between the chromosome and the pSCL4 megaplasmid is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1092970477
P356DOI10.1186/S12864-017-4289-Y
P2888exact matchhttps://scigraph.springernature.com/pub.10.1186/s12864-017-4289-y
P932PMC publication ID5702194
P698PubMed publication ID29178826

P2093author name stringAntonio Rodríguez-García
Paloma Liras
Rubén Álvarez-Álvarez
Yolanda Martínez-Burgo
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Cloning and characterization of a gene encoding the gamma-butyrolactone autoregulator receptor from Streptomyces clavuligerusQ38338806
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Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathwaysQ39680793
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Transcriptomic analysis of liquid non-sporulating Streptomyces coelicolor cultures demonstrates the existence of a complex differentiation comparable to that occurring in solid sporulating culturesQ41851955
Interspecies DNA microarray analysis identifies WblA as a pleiotropic down-regulator of antibiotic biosynthesis in StreptomycesQ42257757
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Holomycin and N-propionylholothin, antibiotics produced by a cephamycin C producerQ44762485
Identification of a cluster of genes that directs desferrioxamine biosynthesis in Streptomyces coelicolor M145.Q45188178
afsQ1-Q2-sigQ is a pleiotropic but conditionally required signal transduction system for both secondary metabolism and morphological development in Streptomyces coelicolorQ46299052
Different proteins bind to the butyrolactone receptor protein ARE sequence located upstream of the regulatory ccaR gene of Streptomyces clavuligerusQ46429005
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Characterization of a negative regulator AveI for avermectin biosynthesis in Streptomyces avermitilis NRRL8165.Q46534592
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A putative two-component signal transduction system regulates sigmaE, a sigma factor required for normal cell wall integrity in Streptomyces coelicolor A3(2).Q47945924
The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) geneQ48037391
Cloning, sequencing and disruption of a gene from Streptomyces clavuligerus involved in clavulanic acid biosynthesisQ48079124
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Cell density influences antibiotic biosynthesis in Streptomyces clavuligerusQ71251388
A versatile quick-prep of genomic DNA from Gram-positive bacteriaQ71968559
Artificial circularization of the chromosome with concomitant deletion of its terminal inverted repeats enhances genetic instability and genome rearrangement in Streptomyces lividansQ73175059
A 1.8-Mb-reduced Streptomyces clavuligerus genome: relevance for secondary metabolism and differentiationQ86890986
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)907
P577publication date2017-11-25
P1433published inBMC GenomicsQ15765854
P1476titleDiscovering the potential of S. clavuligerus for bioactive compound production: cross-talk between the chromosome and the pSCL4 megaplasmid
P478volume18

Reverse relations

cites work (P2860)
Q64242296A putative antimicrobial peptide from Hymenoptera in the megaplasmid pSCL4 of ATCC 27064 reveals a singular case of horizontal gene transfer with potential applications
Q91583836Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism

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