MiR-204 enhances mitochondrial apoptosis in doxorubicin-treated prostate cancer cells by targeting SIRT1/p53 pathway

scientific article published on 23 October 2017

MiR-204 enhances mitochondrial apoptosis in doxorubicin-treated prostate cancer cells by targeting SIRT1/p53 pathway is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.21960
P932PMC publication ID5722564
P698PubMed publication ID29228612

P2093author name stringJing Chen
Bo Xie
Yan Shu
Zhen Liang
Ligang Ren
P2860cites workhSIR2(SIRT1) functions as an NAD-dependent p53 deacetylaseQ24291829
SIRT1 promotes DNA repair activity and deacetylation of Ku70Q24298814
SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activityQ24304342
BOK and NOXA are essential mediators of p53-dependent apoptosisQ24337595
MicroRNAs: target recognition and regulatory functionsQ24609584
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancersQ24625794
Role of microRNAs in the resistance of prostate cancer to docetaxel and paclitaxelQ26769599
Role of microRNAs in chemoresistanceQ26770485
Insights into Chemoresistance of Prostate CancerQ26795589
Cancer statistics, 2015Q27860576
The functions of animal microRNAsQ27860621
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
p53 Acetylation: Regulation and ConsequencesQ28085076
Sirtuins in mammals: insights into their biological functionQ29615248
β2-AR activation induces chemoresistance by modulating p53 acetylation through upregulating Sirt1 in cervical cancer cellsQ33873143
Harnessing the p53-PUMA axis to overcome DNA damage resistance in renal cell carcinomaQ35022460
SIRT1 expression is associated with the chemotherapy response and prognosis of patients with advanced NSCLC.Q35041187
Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95Q36782452
The role of chemotherapy and new targeted agents in the management of primary prostate cancerQ37708171
MicroRNAs and drug resistance in prostate cancersQ38205266
p53 as a target for the treatment of cancer.Q38279586
Influence of microRNAs and Long Non-Coding RNAs in Cancer Chemoresistance.Q38546133
MicroRNA-22 inhibits cell growth and metastasis in breast cancer via targeting of SIRT1.Q38638014
MicroRNA-138 inhibits cell proliferation in hepatocellular carcinoma by targeting Sirt1.Q38662706
miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicinQ38706087
TRIMming p53's anticancer activityQ38742837
Combining p53 stabilizers with metformin induces synergistic apoptosis through regulation of energy metabolism in castration-resistant prostate cancerQ38792069
MicroRNA-101 sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis via targeting Mcl-1.Q38807863
The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death.Q38834894
Synergy of BID with doxorubicin in the killing of cancer cellsQ38901240
miR-204-5p inhibits proliferation and invasion and enhances chemotherapeutic sensitivity of colorectal cancer cells by downregulating RAB22A.Q38949787
MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcomeQ39297570
Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition?Q39905924
SIRT1 promotes epithelial-mesenchymal transition and metastasis in colorectal cancer by regulating Fra-1 expressionQ39921520
Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of NoxaQ40066192
SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stressQ40398454
Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway.Q40977712
MiR-24-BIM-Smac/DIABLO axis controls the sensitivity to doxorubicin treatment in osteosarcomaQ41215178
Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complexQ41233246
microRNA-181 promotes prostate cancer cell proliferation by regulating DAX-1 expressionQ41875279
The role of miR-125b-mitochondria-caspase-3 pathway in doxorubicin resistance and therapy in human breast cancer.Q53220492
P433issue57
P407language of work or nameEnglishQ1860
P304page(s)97313-97322
P577publication date2017-10-23
P1433published inOncotargetQ1573155
P1476titleMiR-204 enhances mitochondrial apoptosis in doxorubicin-treated prostate cancer cells by targeting SIRT1/p53 pathway
P478volume8

Reverse relations

cites work (P2860)
Q92471621Down-regulation of long non-coding RNA HOTAIR inhibits invasion and migration of oesophageal cancer cells via up-regulation of microRNA-204
Q97882657HBx mediated Increase of SIRT1 Contributes to HBV-related Hepatocellular Carcinoma Tumorigenesis
Q92382932Long non-coding RNA MALAT1 activates autophagy and promotes cell proliferation by downregulating microRNA-204 expression in gastric cancer
Q98945434MiR-140 Resensitizes Cisplatin-Resistant NSCLC Cells to Cisplatin Treatment Through the SIRT1/ROS/JNK Pathway
Q58795281MiR-204 acts as a potential therapeutic target in acute myeloid leukemia by increasing BIRC6-mediated apoptosis
Q92952317MiR-204 suppresses cell proliferation and promotes apoptosis in ovarian granulosa cells via targeting TPT1 in polycystic ovary syndrome
Q90642832MicroRNA-204 may participate in the pathogenesis of hypoxic-ischemic encephalopathy through targeting KLLN
Q102323862microRNA-211-mediated targeting of the INHBA-TGF-β axis suppresses prostate tumor formation and growth

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