PRL‑3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients

scientific article published on 20 November 2017

PRL‑3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3892/IJO.2017.4208
P932PMC publication ID5741371
P698PubMed publication ID29207031

P2093author name stringHaitao Zhang
Debasis Mondal
Asim B Abdel-Mageed
David Mulholland
Krzysztof Moroz
Donna R Edwards
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Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancerQ33863328
DD3: a new prostate-specific gene, highly overexpressed in prostate cancerQ33884277
Molecular characterization of human prostate carcinoma cell linesQ34266176
Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cellsQ36384761
Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient SurvivalQ36918028
Association of Prostate Cancer Risk Variants with TMPRSS2:ERG Status: Evidence for Distinct Molecular SubtypesQ36918116
Phosphatase of regenerating liver-3 (PRL-3) is associated with metastasis and poor prognosis in gastric carcinomaQ37426883
PRL‐3 phosphatase and cancer metastasisQ37807363
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The nucleolus: an emerging target for cancer therapyQ38129532
Prostate cancer biomarkers: an update.Q38185176
The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulationQ38261521
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage.Q38467346
Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migrationQ38786529
LEO1 is regulated by PRL-3 and mediates its oncogenic properties in acute myelogenous leukemiaQ39009741
An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancerQ39394220
Phosphatase PRL-3 Is a Direct Regulatory Target of TGFβ in Colon Cancer MetastasisQ39630626
Downregulation of p53 by phosphatase of regenerating liver 3 is mediated by MDM2 and PIRH2.Q39769653
PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directlyQ39851944
Digital image analysis outperforms manual biomarker assessment in breast cancer.Q39967968
Quantitative imaging assay for NF-kappaB nuclear translocation in primary human macrophages.Q40045324
Establishment and characterization of androgen-independent human prostate cancer cell lines, LN-REC4 and LNCaP-SF, from LNCaP.Q40146469
PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activationQ40189743
Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cellsQ40291759
Different subnuclear localization of wild-type and mutant p53 in human prostate-cancer cells.Q41260779
Overexpression of phosphatase of regenerating liver-3 in breast cancer: association with a poor clinical outcomeQ43685496
Tumor immunobiological differences in prostate cancer between African-American and European-American men.Q44513168
PRL-3 facilitates angiogenesis and metastasis by increasing ERK phosphorylation and up-regulating the levels and activities of Rho-A/C in lung cancerQ46157962
Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancerQ47811299
Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells.Q51587005
PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.Q51798437
Association of ERG and TMPRSS2-ERG with grade, stage, and prognosis of prostate cancer is dependent on their expression levels.Q53519887
E-cadherin expression in prostate cancer: a broad survey using high-density tissue microarray technology.Q53999986
The prognostic role of the pathological T2 subclassification for prostate cancer in the 2002 Tumour-Nodes-Metastasis staging systemQ57307229
Pathological T2 sub-divisions as a prognostic factor in the biochemical recurrence of prostate cancerQ84419666
PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolismQ88727073
P4510describes a project that usesImageJQ1659584
P577publication date2017-11-20
P1433published inInternational Journal of OncologyQ6051527
P1476titlePRL‑3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients

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cites work (P2860)
Q60950173A Rapid Method for the Detection of Sarcosine Using SPIONs/Au/CS/SOX/NPs for Prostate Cancer Sensing
Q57029048Molecular network-based identification of competing endogenous RNAs and mRNA signatures that predict survival in prostate cancer

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